Persistent Hard Growth in the Upper Jaw: Dental Insights - Dentistry

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There is a hard lump on the upper jaw?


Hello, Doctor.
Last March, I discovered a hard, flesh-colored lesion in my upper jaw, approximately 0.1-0.2 mm in size.
It is painless and does not itch.
It has not disappeared and feels solid; when I touch it with a cotton swab, it does not hurt, cannot be moved, and is hard.
At that time, I went to an ENT specialist for excision and biopsy, and the doctor explained that it was benign.
One to two months later, it grew back.
In June, I had a second excision, and the doctor again explained that it was benign.
About a month later, it grew back again.
Upon my follow-up visit, since it had been excised twice, the doctor advised me to monitor it.
As of now, it is still present, and I feel it has not significantly increased in size or changed, but I remain anxious and concerned.
I would like to ask for your advice.
Below are the two biopsy reports:
112/03
[Pathological Diagnosis] Fibrosis, oral cavity, excision.
[Pathology Report] Gross description: Specimen received, labeled as oral region, consists of one fragment of grayish-tan formalin-fixed tissue, measuring 0.2 x 0.1 x 0.1 cm in size.
Specimen is submitted totally for section.
Microscopic Examination: The section reveals chronic inflammatory cell infiltration and fibrosis.
The IHC stain of CK and P40 confirms the interpretation.
[Ref] CSP21-05388 Chronic inflammation, right hypopharynx, excision.
Fibrosis, oral cavity, excision.
112/6
[Pathological Diagnosis] Epithelial hyperplasia with hyperkeratosis, oral mucosa, excision.
[Pathology Report] Gross description: Specimen received, labeled as oral region, consists of one fragment of grayish-tan formalin-fixed tissue, measuring 0.1 x 0.1 x 0.1 cm in size.
The specimen is submitted totally for section.
Microscopic Examination: The section reveals hyperplasia of squamous epithelium with hyperkeratosis.
[Ref] CSP23-05658 Fibrosis, oral cavity, excision.
CSP21-05388 Chronic inflammation, right hypopharynx, excision.
Epithelial hyperplasia with hyperkeratosis, oral mucosa, excision.
1.
Do I need any treatment?
2.
Is the squamous epithelial hyperplasia mentioned in the report a precancerous condition?
3.
Is excessive keratinization considered a pathological condition?
4.
Should I consider another excision for biopsy, or will it just grow back?
5.
I previously consulted a doctor at a clinic who suggested it might be like a scar (is it possible that it is currently very hard, like bone?).
6.
Please help me interpret last year's two biopsy reports (the contents of the two reports differ somewhat; could this be due to changes in the lesion?).
Thank you for taking the time to assist me.
I am still unable to find peace and feel anxious.

Aa, 30~39 year old female. Ask Date: 2024/04/14

Dr. Zeng Guanghui reply Dentistry


Hello Ms.
Aa: I apologize for not being able to provide a detailed response.
I recommend visiting a medical center for further examination or treatment in the oral surgery or otolaryngology department.
Dr.
Tseng Guang-Hui from Nantou Hospital's dental department.

Reply Date: 2024/04/14

More Info


It sounds like you are dealing with a persistent hard growth in your upper jaw that has been evaluated and removed twice, with both pathology reports indicating benign conditions. Let's address your questions and concerns based on the information provided.

1. Treatment Recommendations: Given that the growth has recurred after two excisions, it may be beneficial to consult with an oral surgeon or a specialist in oral pathology for a more comprehensive evaluation. They may consider imaging studies, such as a CT scan, to assess the underlying bone structure and any potential changes that may not be visible externally. If the growth continues to recur, further surgical intervention may be warranted, but this should be discussed in detail with your healthcare provider.

2. Squamous Epithelium Hyperplasia and Precancerous Lesions: The report indicating "epithelial hyperplasia with hyperkeratosis" suggests an increase in the number of cells in the squamous epithelium, which is the type of tissue that lines the oral cavity. While hyperplasia itself is not cancerous, it can be associated with irritation or chronic inflammation. It is essential to monitor this condition, as persistent irritation can sometimes lead to dysplastic changes, which are precursors to cancer. However, your reports do not indicate dysplasia at this time.

3. Hyperkeratosis: Hyperkeratosis refers to the thickening of the outer layer of the skin or mucous membranes. In the context of your reports, it is often a response to chronic irritation or inflammation. While it is not inherently a disease, it can be a sign of an underlying issue that needs to be addressed. If the hyperkeratosis persists, it may warrant further investigation to determine the cause of the irritation.

4. Further Excision and Recurrence: The decision to excise the growth again should be made in consultation with your healthcare provider. If the growth is benign and not causing any symptoms, some practitioners may recommend a watchful waiting approach. However, if you are experiencing anxiety about the growth, discussing your concerns with a specialist may help you feel more at ease. Recurrence is possible, especially if the underlying cause of the growth is not addressed.

5. Scar Tissue Consideration: The description of the growth feeling hard, similar to bone, could suggest the presence of scar tissue or fibrosis, which can occur after surgical excision. Scar tissue can sometimes feel firmer than the surrounding tissue and may not necessarily indicate a new growth. However, it is essential to have this evaluated by a professional to rule out any other conditions.

6. Interpreting Pathology Reports: The differences in your pathology reports may reflect the dynamic nature of your condition. The first report indicated chronic inflammation and fibrosis, while the second report showed hyperplasia with hyperkeratosis. These findings suggest that the tissue has undergone changes over time, likely in response to ongoing irritation or inflammation. It is not uncommon for pathology findings to evolve, and this should be discussed with your healthcare provider to understand the implications for your treatment and management.

In summary, while the growths you have experienced have been classified as benign, ongoing monitoring and consultation with specialists are crucial. If you continue to have concerns or if the growth changes, do not hesitate to seek further evaluation. Your peace of mind is important, and addressing your anxiety about this condition is a valid part of your healthcare journey.

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