Prolonged Penile Injury: Treatment and Concerns - Urology

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The foreskin abrasion has been treated for over one month?


Dear Director Li,
Due to work commitments, I am unable to return to Taiwan for a consultation in the short term and would like to seek your professional advice.

On February 21, I engaged in sexual intercourse without lubrication, which resulted in a foreskin abrasion.
From February 25 to February 27, I applied a topical ointment called Ruankang (no improvement).
From February 28 to March 1, I used Lifu ointment (still no improvement, and the wound area gradually expanded).
From March 2 to March 11, I visited a urologist who prescribed oral Cefadroxil and topical tetracycline eye ointment.
Tests were ordered for syphilis, HIV, herpes simplex IgM, and a urinalysis.

On March 12 to March 18, I returned for a follow-up, and the doctor stated that all tests were normal.
I was prescribed oral Amoxicillin and topical Pidaifu cream.
Initially, there was only a wound on the foreskin, but this week, I started to develop a wound on the glans as well.
From March 19 to March 25, I returned for another follow-up, and the doctor continued to prescribe oral Amoxicillin and topical Pidaifu cream (slight improvement, the wound was less red).

From March 26 to April 1, during my follow-up, the doctor noted that the wound appeared somewhat dry and changed the prescription to topical Winston Bidar ointment, without prescribing any oral medication.
After using this ointment for a week, the wound worsened and became redder.
On April 2, I returned for a follow-up.
The doctor observed the worsening of the wound and suspected it might be herpes, prescribing oral Acyclovir and topical Spersin ointment.
Tests were ordered for herpes simplex IgG and Chlamydia antibodies.
Upon reviewing the ingredients of Spersin at home, I discovered that Ruankang, Lifu, Bidar, and Spersin all contain Neomycin.
Whenever I apply ointments containing this ingredient, my wound worsens.
I did not use the Spersin ointment and only took Acyclovir.

On April 5, I consulted a dermatologist.
At this point, the foreskin had retracted, and the wound was secreting a large amount of thick fluid, with pain resembling multiple cuts from a utility knife.
I informed the dermatologist about my previous treatment at the urology clinic, and he prescribed oral Doxycycline, Ibuprofen, Dexamethasone, and Strocain; administered an injection of Lincomycin; and prescribed topical Gentamicin ointment.

As of April 14 (I am currently abroad), I have been following the dermatologist's instructions for medication and topical treatment.
The secretion of thick fluid from the wound has gradually decreased, and the pain has slightly improved.
I checked the hospital's website for the blood test results from April 2: Herpes Simplex IgG: <0.5, Chlamydia Ab (TIP): 8.0 RU/ml.
I would like to ask you, Director:
1.
Both Herpes Simplex IgM and IgG are <0.5, but the urologist prescribed Acyclovir before the test results were available.
I followed the prescription for a week; what impact could this have on my body?
2.
How should I interpret the Chlamydia Ab (TIP) result of 8.0 RU/ml?
3.
Since my wound worsens whenever I apply ointments containing Neomycin, could I be allergic to this ingredient, or could there be other factors involved?
4.
After more than a month of using medications, especially topical antibiotics for such an extended period, will this affect the skin of the foreskin and glans, potentially causing thinning or other effects? Will there be any other impacts on my body?

Anderson, 30~39 year old female. Ask Date: 2024/04/14

Dr. Li Minghui reply Urology


Hello: Regarding your situation: This facility is unable to provide a diagnosis, as it is mostly due to the presence of wounds and subsequent poor care.
Taking ACYCLOVIR before detection will not pose significant issues, unless there is an allergy.
The interpretation of the presence of bacteria requires standard values, and NEOMYCIN is commonly used; if there are repeated adverse reactions, it should be avoided.
If the wound does not heal over a long period, there may be risks of pigmentation, scarring, or narrowing.
Currently, it is important to take good care of the wound, keeping it clean and dry, paying attention to diet, and temporarily avoiding sexual activity.
Wishing you good health.

Reply Date: 2024/04/14

More Info


Dear Patient,
Thank you for reaching out regarding your prolonged penile injury and the treatment concerns you have been experiencing. I understand that this situation can be quite distressing, and I will do my best to address your questions based on the information provided.

1. Impact of Acyclovir Usage: Acyclovir is an antiviral medication primarily used to treat infections caused by certain types of viruses, including herpes. Since your IgM and IgG results for herpes simplex virus were both <0.5, it indicates that there is no active herpes infection. Taking Acyclovir in this case may not have been necessary, but it is generally considered safe and well-tolerated. If you have no known allergies to Acyclovir, it should not cause any adverse effects on your body. However, unnecessary use of any medication can lead to potential side effects, so it’s always best to use medications that are indicated for your specific condition.

2. Chlamydia Ab (TIP) Result: The result of 8.0 RU/ml for Chlamydia antibodies suggests a positive test for Chlamydia infection. This means that you may have been exposed to the bacteria at some point. It is important to follow up with your healthcare provider to discuss the implications of this result, as untreated Chlamydia can lead to complications. Your doctor may recommend further testing or treatment based on your clinical presentation and history.

3. Possible Allergy to Neomycin: Given your experience of worsening symptoms upon applying medications containing Neomycin, it is plausible that you may have developed an allergic reaction to this ingredient. Neomycin is known to cause contact dermatitis in some individuals, leading to redness, irritation, and worsening of existing wounds. It would be advisable to avoid any topical products containing Neomycin in the future and inform your healthcare providers of this sensitivity.

4. Long-term Effects of Prolonged Medication Use: Prolonged use of topical antibiotics and corticosteroids can potentially lead to skin thinning, especially in sensitive areas such as the genital region. However, the extent of this effect can vary based on individual skin types and the specific medications used. It is essential to monitor your skin condition and report any changes to your healthcare provider. They may suggest alternative treatments or a tapering schedule for any ongoing medications to minimize potential side effects.

In conclusion, it is crucial to maintain open communication with your healthcare providers regarding your treatment plan and any adverse reactions you experience. If your symptoms persist or worsen, consider seeking a second opinion or further evaluation from a specialist. Additionally, ensure that you are following up on the Chlamydia test results and any necessary treatments.

I hope this information helps clarify your concerns, and I wish you a swift recovery.

Best regards,
Doctor Q&A Teams

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