Pregnancy Signs: When to Test and Seek Medical Advice - Obstetrics and Gynecology

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Are you pregnant?


Hello Doctor, I am currently trying to conceive.
My menstrual cycle is about 28-35 days, and I experience severe premenstrual syndrome before my period, including fatigue, increased discharge, breast tenderness, pain on both sides of my abdomen, lower back pain, tiredness, excessive sleepiness, and more.
My last menstrual period was from April 8 to April 12.
I started taking ovulation medication for five days from April 12.
We had intercourse on April 21, April 23, April 25, and April 27 (on this day, I noticed clear cervical mucus).
As of today, May 13, I have not had my period.
During this time, I have not detected a strong positive on ovulation tests, and the second line has been getting fainter.
I tested for pregnancy on May 9 and May 12, but both tests only showed one line.
I have experienced lower back pain and itchy nipples during this period (with my first pregnancy, I had itchy nipples before getting a positive test), and I have also noticed clear discharge.
Additionally, I have been feeling dizzy, nauseous, excessively sleepy, and fatigued.
I would like to ask the doctor if I should wait and test again, or if I should go directly to the hospital, or if this means I am not pregnant.
Thank you.

Guan, 30~39 year old female. Ask Date: 2024/05/13

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, is it enough to take a pregnancy test to determine if you are pregnant? Wishing you good health.

Reply Date: 2024/05/13

More Info


When it comes to understanding pregnancy signs and when to seek medical advice, it’s important to consider several factors, especially if you are actively trying to conceive. Based on your description, you have been experiencing various symptoms that could indicate pregnancy, but you have also had negative pregnancy tests. Here’s a breakdown of your situation and some guidance on what to do next.

Firstly, your menstrual cycle, which ranges from 28 to 35 days, is relatively normal, but it can vary from month to month. You mentioned that your last menstrual period was from April 8 to April 12, and you have been taking ovulation medication since April 12. You had unprotected intercourse on several days around your ovulation window, which is a good strategy for conception.

The symptoms you are experiencing—such as fatigue, increased discharge, breast tenderness, abdominal pain, and sleepiness—are indeed common signs of early pregnancy. However, these symptoms can also be attributed to premenstrual syndrome (PMS) or the hormonal changes induced by the ovulation medication you are taking.
You have conducted pregnancy tests on May 9 and May 12, both of which returned negative results. It’s important to note that home pregnancy tests are most reliable when taken after a missed period. Since your expected period is around May 13, it may still be too early to detect pregnancy accurately, especially if implantation has just occurred or if your hormone levels are not yet high enough to be detected by the test.

Given that you have experienced symptoms like breast itching and increased discharge, which you noted were similar to your first pregnancy, it’s understandable to feel anxious. However, the absence of a positive pregnancy test could suggest that you are not pregnant this cycle.
Here are a few recommendations on what to do next:
1. Wait a Few Days: Since your expected period is around May 13, it may be beneficial to wait a few days and test again. If your period does not arrive, try using a more sensitive pregnancy test or consult with your healthcare provider for a blood test, which can detect lower levels of hCG (the pregnancy hormone) than home tests.

2. Monitor Symptoms: Keep track of your symptoms. If they persist or worsen, or if you experience any unusual symptoms (such as severe abdominal pain or heavy bleeding), it’s important to seek medical advice sooner.

3. Consult Your Doctor: If you continue to receive negative tests and your period does not start, it would be wise to consult your healthcare provider. They can perform a more thorough evaluation, including a blood test and possibly an ultrasound, to determine if you are pregnant or if there are other underlying issues.

4. Consider Stress and Hormonal Factors: Sometimes, stress and hormonal fluctuations can affect your cycle and symptoms. Ensure you are managing stress levels and maintaining a healthy lifestyle, as these factors can influence your menstrual cycle and overall reproductive health.

In conclusion, while your symptoms may suggest a possibility of pregnancy, the negative tests indicate that it might be too early to confirm. Waiting a few days and retesting, along with monitoring your symptoms, will provide more clarity. If in doubt, don’t hesitate to reach out to your healthcare provider for personalized advice and support.

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