Safe Eye Drops During Pregnancy: What You Need to Know - Obstetrics and Gynecology

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Pregnancy Eye Medication Consultation


Hello, doctor.
I am currently 6 weeks pregnant and frequently use a computer at work.
I use Santen eye drops from Japan to relieve eye fatigue.
I would like to know if its ingredients are suitable for use during pregnancy.
Thank you!
Ingredients:
- Vitamin B12 (Cyanocobalamin) ~ 0.02%
- Sodium Chondroitin Sulfate ~ 0.5%
- Vitamin B6 (Pyridoxine Hydrochloride) ~ 0.1%
- Neostigmine Methylsulfate ~ 0.002%
- Taurine ~ 0.1%
- Dipotassium Glycyrrhizinate ~ 0.1%
- Chlorpheniramine Maleate ~ 0.01%
- Tetrahydrozoline Hydrochloride ~ 0.03%
Other ingredients (excipients):
- ε-Aminocaproic Acid
- Disodium Edetate Hydrate
- Chlorobutanol
- Geraniol
- Dextran 70
- Hydroxyethylcellulose
- Benzalkonium Chloride Solution
- Polysorbate 80
- d-Camphor
- l-Menthol
- Isotonic agents (Boric Acid, Sodium Chloride, Potassium Chloride)
- pH adjusters (Dilute Hydrochloric Acid, Sodium Borate)
- Purified Water.

Weiwei, 30~39 year old female. Ask Date: 2024/05/15

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it should not have any impact.
Wishing you good health.

Reply Date: 2024/05/15

More Info


When it comes to using eye drops during pregnancy, especially in the early stages, it is crucial to consider both the safety of the medication and the potential effects on the developing fetus. In your case, you are currently six weeks pregnant and are using a Japanese eye drop product that contains several active ingredients, including Vitamin B12, Sodium Chondroitin Sulfate, Vitamin B6, Neostigmine Methylsulfate, Taurine, Dipotassium Glycyrrhizinate, Chlorpheniramine Maleate, and Tetrahydrozoline Hydrochloride, among others.


Safety of Eye Drops During Pregnancy
1. General Guidelines: During the first trimester, which is a critical period for fetal development, it is generally advised to avoid medications unless absolutely necessary. This is because the embryo is particularly sensitive to external substances, and any potential teratogenic effects (those that could cause malformations) are of significant concern.

2. Active Ingredients:
- Tetrahydrozoline Hydrochloride is a vasoconstrictor commonly used in eye drops to relieve redness. While there is limited data on its safety during pregnancy, it is generally recommended to use it cautiously.

- Chlorpheniramine Maleate is an antihistamine that can cause sedation and may not be the best choice during pregnancy, especially if you are sensitive to its effects.

- The other ingredients, such as Vitamins B6 and B12, are generally considered safe and are often recommended during pregnancy for their nutritional benefits.

3. Consultation with Healthcare Providers: It is essential to discuss any medication, including over-the-counter products like eye drops, with your healthcare provider. They can provide personalized advice based on your medical history and the specifics of your pregnancy.

4. Alternative Remedies: If you are experiencing eye fatigue due to prolonged computer use, consider non-pharmacological approaches such as:
- Frequent Breaks: Follow the 20-20-20 rule—every 20 minutes, look at something 20 feet away for at least 20 seconds.

- Warm Compresses: Applying a warm, damp cloth over your eyes can help relieve discomfort.

- Proper Lighting: Ensure that your workspace is well-lit to reduce strain on your eyes.

- Artificial Tears: If dryness is an issue, preservative-free artificial tears may be a safer alternative to lubricate your eyes without the risks associated with medicated drops.

5. Monitoring Symptoms: Keep track of your symptoms. If you notice any significant changes in your vision, increased discomfort, or other concerning symptoms, seek medical attention promptly.


Conclusion
While the eye drops you are using contain several ingredients, some of which may not be ideal during pregnancy, it is crucial to weigh the benefits against the potential risks. Always consult with your healthcare provider before continuing or starting any medication during pregnancy. They can help you determine the safest options for managing eye fatigue and discomfort while ensuring the health and safety of both you and your developing baby.

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