Managing Slow Heart Rate: Concerns with KanKen and XinLiZheng Medications - Cardiology

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Bradycardia, issues with the use of Heart Rate Regulating medications such as Cardizem and Concor?


Hello, Doctor.
I have hypothyroidism, which has been well-controlled with medication for many years.
Last August, I experienced chest tightness, chest pain, and fatigue, and was diagnosed with premature contractions in both the ventricles and atria.
My doctor prescribed Concor 1.25 mg, half a tablet daily, which gradually reduced my chest discomfort to occasional episodes two or three times a month.
However, recently, it seems that similar symptoms have started to occur more frequently.
During my regular check-up, the doctor noted that my heart rate was slow, measuring around 53 bpm at the time of the visit.
He asked whether my heart rate increased or decreased during episodes, and since my recent discomfort mostly occurred while at rest, I checked my fitness watch data and found that my heart rate suddenly jumped to between 80-102 bpm, then returned to normal within a few minutes, followed by recurring discomfort.
I informed the doctor that my heart rate "increased." He concluded that I have an irregular type of arrhythmia that fluctuates between fast and slow rates, and he prescribed Rythmol 150 mg to be taken only when I feel unwell.
My concern is that after returning home, I experienced one or two more episodes of discomfort, during which my heart rate dropped below 50 bpm, or did not noticeably increase; I only experienced angina, chest tightness, and fatigue.
This situation leaves me uncertain about whether I should take Rythmol.
Since starting Concor, my heart rate has dropped to the 30s during sleep, and my average resting heart rate while watching TV or browsing the internet is around 46 bpm.
Despite having started a regular exercise routine after being diagnosed with heart issues, my long-term poor sleep quality and recent fatigue have made me reluctant to exercise.
Should I try to follow the doctor's advice and take Rythmol, or should I discuss my medication with my doctor again? The doctor has a very high patient volume, making it difficult to schedule an appointment, and I always feel very fatigued during visits.
My next appointment is not for another three months, so I wanted to ask for your opinion first.
Thank you.

Miss Tang, 50~59 year old female. Ask Date: 2024/06/03

Dr. He Dongjin reply Cardiology


Hello, feeling very fatigued could be due to a slow heart rate or hypothyroidism.
It is recommended to consider medications that improve sleep.
Regarding the medication Heartil, my suggestion is to hold off on taking it for now and observe your condition.
Changhua Hospital cares about you.

Reply Date: 2024/06/03

More Info


Managing a slow heart rate, especially in the context of medications like KanKen (Carvedilol) and XinLiZheng (a heart rhythm medication), can be complex and requires careful consideration of your overall health status, symptoms, and medication effects.

From your description, it appears that you have a history of hypothyroidism, which is well-controlled with medication. However, you have also experienced symptoms such as chest discomfort, fatigue, and irregular heartbeats, leading to the prescription of KanKen. This medication is a beta-blocker that can help manage heart rate and blood pressure but may also contribute to a lower heart rate (bradycardia). It is not uncommon for patients on beta-blockers to experience a heart rate that drops below the normal range, particularly if they are sensitive to the medication or if the dosage is higher than necessary.

You mentioned that your heart rate has dropped to the 30s during sleep and averages around 46 while at rest. These rates are significantly lower than the typical resting heart rate of 60-100 beats per minute. While some individuals, particularly athletes, may have lower resting heart rates, a heart rate consistently below 50, especially if accompanied by symptoms like fatigue and chest discomfort, warrants further evaluation.

The addition of XinLiZheng (likely a medication for managing arrhythmias) suggests that your healthcare provider is concerned about the irregular heartbeats you are experiencing. The fact that your heart rate fluctuates between 50 and over 100 during episodes of discomfort indicates that you may be experiencing paroxysmal atrial fibrillation or another form of arrhythmia. This can be distressing and may require adjustments in your treatment plan.

Given your concerns about whether to take XinLiZheng, it is essential to weigh the benefits and risks. If you are experiencing episodes of discomfort and your heart rate drops significantly, it may be prudent to follow your doctor's advice and take the medication as prescribed. However, if you feel that the medication is contributing to your symptoms or if you are experiencing side effects, it is crucial to communicate this to your healthcare provider.

Since you mentioned difficulties in scheduling follow-up appointments due to the high patient volume, consider reaching out to your healthcare provider's office for advice. They may be able to provide guidance over the phone or through a telehealth appointment, which could be more convenient given your fatigue and the challenges you face in attending in-person visits.

In summary, managing a slow heart rate while on medications like KanKen and XinLiZheng requires careful monitoring of your symptoms and heart rate. It is essential to maintain open communication with your healthcare provider about your experiences, especially if you notice significant changes in your heart rate or if you have concerns about the medications. If you continue to experience low heart rates and symptoms of discomfort, further evaluation may be necessary, which could include additional heart monitoring or adjustments to your medication regimen. Your health and safety should always be the priority, so do not hesitate to seek clarification and support from your medical team.

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