Intravitreal pharmacotherapy for macular degeneration with neovascularization?
Hello, Doctor.
My mother, who is 72 years old, was diagnosed with macular degeneration with neovascularization in her right eye this January.
She is undergoing intravitreal injections, and after approval from the National Health Insurance, she has received four out of eight subsidized injections.
However, after the fourth injection, her vision does not seem to have improved significantly.
When we inquired with her attending physician, we were informed that there is currently a vitreous hemorrhage obstructing her vision, but this condition is irreversible.
Given that my mother has congenital weakness in her left eye and is currently experiencing macular degeneration in her right eye, her daily vision is affecting her quality of life.
I would like to ask the doctor: 1.
Is it possible for the vitreous hemorrhage to gradually resolve after the injections, or are there other treatment options available? 2.
Is it necessary to complete all eight injections for her to achieve full recovery? Thank you, Doctor, for your assistance in answering these questions.
Ms. Li, 40~49 year old female. Ask Date: 2024/06/11
Dr. He Jianxian reply Ophthalmology
Dear Ms.
Li:
1.
Scabbing is an irreversible condition, and there is currently no appropriate treatment available.
2.
Based on your description, the condition can only be stabilized and cannot be restored to the state prior to the illness.
Director He Jianxian, Ophthalmology, Nantou Hospital
Reply Date: 2024/06/11
More Info
Managing macular degeneration, particularly when complicated by conditions such as neovascularization, can be a challenging journey for both patients and their families. Your mother’s situation, with her recent diagnosis of macular degeneration and the need for intravitreal injections, is not uncommon. Intravitreal injections, such as Eylea (aflibercept), are often used to treat age-related macular degeneration (AMD) and can help manage the growth of abnormal blood vessels in the retina.
1. Post-Injection Scarring and Recovery: After receiving intravitreal injections, some patients may experience scarring or the formation of a membrane over the macula, which can obstruct vision. This scarring, often referred to as epiretinal membrane or macular pucker, can sometimes resolve on its own, but in other cases, it may require additional treatment. The healing process can vary significantly from person to person. While some patients may notice gradual improvement in their vision over time, others might not see significant changes. If the scarring is substantial and affecting vision, a surgical procedure called vitrectomy may be considered to remove the membrane. It’s essential to have an open dialogue with your mother’s ophthalmologist about the potential for recovery and the options available if the scarring persists.
2. Completion of Treatment: The treatment regimen for macular degeneration often involves multiple injections over a specified period, typically ranging from several months to a year. While some patients may experience improvement after a few injections, others may need to complete the full course of treatment to assess the overall effectiveness. It’s crucial to follow the treatment plan as prescribed by the ophthalmologist, as this maximizes the chances of stabilizing or improving vision. However, if there are concerns about the effectiveness of the treatment or if vision does not improve, it’s important to discuss these issues with the healthcare provider. They may recommend additional diagnostic tests, such as optical coherence tomography (OCT), to evaluate the retina's condition and determine the best course of action.
In terms of managing your mother’s overall eye health and supporting her recovery, consider the following:
- Regular Follow-ups: Ensure that your mother attends all scheduled follow-up appointments. These visits are critical for monitoring her condition and adjusting treatment as necessary.
- Healthy Diet: Encourage a diet rich in antioxidants, omega-3 fatty acids, and vitamins C and E, which are beneficial for eye health. Foods such as leafy greens, fish, nuts, and fruits can contribute positively to retinal health.
- Lifestyle Modifications: Protecting her eyes from UV light by wearing sunglasses, managing blood sugar levels if she has diabetes, and avoiding smoking can also help maintain her vision.
- Vision Rehabilitation: If her vision continues to be affected, consider exploring vision rehabilitation services. These programs can provide strategies and tools to help her adapt to changes in her vision and maintain independence.
In conclusion, managing macular degeneration is a multifaceted process that requires patience and collaboration with healthcare providers. While the journey may be challenging, staying informed and proactive about treatment options can significantly impact your mother’s quality of life. Always feel free to ask her ophthalmologist any questions or express concerns regarding her treatment and recovery process.
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