Long-Term Use of Eye Drops: Safety and Effects on Eye Health - Ophthalmology

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When it comes to the long-term use of eye drops, particularly those prescribed for conditions such as acute toxic conjunctivitis and dry eye syndrome, it is essential to consider both the active ingredients in the medications and the potential implications for eye health. In your case, you mentioned using "Gentamicin" (見大黴素) and "抗耐黴素" (which likely refers to an antifungal eye drop) along with artificial tears.

Question 1: Safety of Long-Term Use of Gentamicin and Antifungal Eye Drops
Gentamicin is an antibiotic that is effective against a variety of bacterial infections. While it can be beneficial for treating infections, long-term use of antibiotic eye drops can lead to several issues. One of the primary concerns is the potential for developing antibiotic resistance, which can make future infections harder to treat. Additionally, prolonged use of any medication can lead to side effects, including irritation, allergic reactions, or changes in the normal flora of the eye.

Regarding the presence of steroids in these eye drops, it is crucial to check the specific formulation. Gentamicin itself does not contain steroids, but some formulations may combine antibiotics with steroids to reduce inflammation. If you are unsure, it is best to consult your prescribing physician or pharmacist for clarification.


Question 2: Impact of Orthokeratology on Eye Health
As for your concern about the repeated episodes of conjunctivitis possibly being related to the use of orthokeratology lenses, it is indeed possible. Orthokeratology involves wearing specially designed contact lenses overnight to reshape the cornea temporarily. While this can be effective for myopia control, it can also increase the risk of eye infections and inflammation if the lenses are not properly cared for or if they are worn for extended periods.

The symptoms you describe, such as dry eyes and elevated intraocular pressure (IOP), can also be exacerbated by the use of contact lenses. Dry eyes can lead to discomfort and may increase the risk of infections, including conjunctivitis. The fact that your IOP readings are on the higher side (21-23 mmHg) is concerning, especially if you are already on medication to lower it. Elevated IOP can be a risk factor for glaucoma, so it is essential to monitor this closely with your eye care provider.


Recommendations
1. Regular Monitoring: Given your complex eye health status, including the diagnoses of acute toxic conjunctivitis, dry eye syndrome, and elevated IOP, regular follow-ups with your ophthalmologist are crucial. They can assess the effectiveness of your current treatment plan and make necessary adjustments.

2. Consider Lens Use: If your conjunctivitis episodes continue, it may be worth discussing with your doctor whether to temporarily discontinue the use of orthokeratology lenses. They may suggest alternative methods for vision correction that pose less risk to your eye health.

3. Artificial Tears: Using preservative-free artificial tears can help alleviate dry eye symptoms without the risk of irritation from preservatives found in some eye drops. This can be particularly beneficial if you are using eye drops frequently.

4. Hygiene Practices: Ensure that you are practicing good hygiene with your contact lenses, including proper cleaning and storage, to minimize the risk of infections.

5. Educate Yourself: Understanding the medications you are using, including their potential side effects and interactions, can empower you to make informed decisions about your eye health.

In conclusion, while the medications you are using can be effective for treating your conditions, long-term use should be approached with caution. Regular consultations with your eye care provider will help ensure that your treatment plan is safe and effective for your unique situation.