Lip Swelling: Causes and Concerns in Internal Medicine - Internal Medicine

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Hello, Dr.
Ko...
In the past month or two, I have often woken up to find my lips unusually swollen, sometimes the upper lip and sometimes the lower lip.
I also frequently feel a sense of fullness in my esophagus.
I had surgery for thyroid enlargement about six or seven years ago.
Recently, when I visited a doctor, I was diagnosed with lymphedema.
I would like to ask the doctor, what is lymphedema? I have been applying the ointment prescribed by the doctor as directed, but I have not seen any improvement.
I would like to ask Dr.
Ko why my lips are unusually swollen? Could this be a symptom related to menopause? Thank you...

Lu, 40~49 year old female. Ask Date: 2001/01/29

Dr. Ke Zhengchang reply Internal Medicine


Dear Ms.
Lu Meixia: The possible cause of lymphedema may be hypothyroidism.
The effectiveness of topical ointment treatment is not satisfactory.
It is recommended that you visit the endocrinology clinic for examination and treatment of thyroid function.

Reply Date: 2001/01/29

More Info


Lip swelling, or cheilitis, can be a concerning symptom that may arise from various underlying causes. In your case, the swelling of your lips, along with the sensation of fullness in your esophagus, could be linked to several factors, including lymphatic issues, hormonal changes, or allergic reactions.
Understanding Lymphatic Edema:
Lymphatic edema, or lymphedema, occurs when there is an accumulation of lymph fluid in the tissues, often due to a blockage or damage to the lymphatic system. This can lead to swelling in various parts of the body, including the lips. In your case, if your physician has diagnosed you with lymphedema, it may be related to your previous thyroid surgery, which could have affected the lymphatic drainage in your neck area.
Lymphedema can be primary (genetic) or secondary (acquired due to injury, surgery, or infection). The swelling can be localized or generalized, and it may fluctuate based on various factors, including activity level, diet, and fluid intake. Treatment typically involves compression therapy, manual lymphatic drainage, and skin care to prevent infections.

Other Possible Causes of Lip Swelling:
1. Allergic Reactions: Allergies to food, medications, or environmental factors can cause localized swelling. If you have recently introduced new foods or medications into your routine, consider discussing these with your doctor.


2. Hormonal Changes: Hormonal fluctuations, particularly during menopause, can lead to various symptoms, including swelling and changes in skin texture. While hormonal changes can affect fluid retention and tissue swelling, they are less commonly associated with isolated lip swelling.

3. Infections: Infections, such as herpes simplex virus or bacterial infections, can cause swelling and inflammation of the lips. If you notice any sores or lesions, this could be a contributing factor.

4. Angioedema: This is a deeper swelling that can affect the lips and is often associated with allergic reactions or certain medications. It can be life-threatening if it affects the throat, leading to difficulty breathing.

5. Nutritional Deficiencies: Deficiencies in certain vitamins and minerals, such as vitamin B12 or iron, can lead to swelling and other oral symptoms.

Management and Next Steps:
Since you mentioned that the topical medication prescribed by your doctor has not shown improvement, it may be beneficial to follow up with your healthcare provider. They may consider further evaluation, such as blood tests to check for allergies, nutritional deficiencies, or other underlying conditions.
In the meantime, keeping a diary of your symptoms, including any potential triggers (foods, activities, stress levels), can help identify patterns that may assist your doctor in diagnosing the issue.
Additionally, maintaining good hydration, a balanced diet, and proper skin care can help manage symptoms. If you experience any difficulty breathing, swelling of the throat, or other severe symptoms, seek immediate medical attention.

In conclusion, while lymphatic edema may be a contributing factor to your lip swelling, it is essential to consider other potential causes and work closely with your healthcare provider to determine the most appropriate treatment plan.

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