Can Tadalafil and Finasteride be taken together?
Hello Dr.
Tsai, I have been experiencing issues with male pattern baldness and started taking finasteride.
Initially, I was on Propecia, but later switched to finasteride.
However, I have experienced significant side effects such as erectile dysfunction and premature ejaculation.
As a result, I began taking 5mg of tadalafil daily.
I have the following questions for you: 1.
Can these two medications be taken together "daily and long-term"? 2.
If I want to discontinue tadalafil, should I gradually extend the intervals between doses or stop completely? 3.
After how long of taking tadalafil would you recommend discontinuation? Thank you, Dr.
Tsai.
Jian Xiansheng, 20~29 year old female. Ask Date: 2024/07/17
Dr. Cai Zhuorong reply Urology
1.
It is possible.
2.
Medication can be stopped directly.
3.
It should be determined based on individual needs.
Reply Date: 2024/07/17
More Info
When considering the concurrent use of Tadalafil and Finasteride, it is essential to understand the pharmacological profiles of both medications and their potential interactions. Tadalafil is primarily used to treat erectile dysfunction and pulmonary hypertension, while Finasteride is commonly prescribed for conditions like benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness).
1. Can Tadalafil and Finasteride be taken together long-term?
Yes, Tadalafil and Finasteride can be taken together safely for an extended period. Clinical studies and literature do not indicate any significant drug interactions between these two medications. Finasteride works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), which can help with hair loss and prostate enlargement. On the other hand, Tadalafil works by increasing blood flow to the penis, helping to achieve and maintain an erection. Since they act through different mechanisms, their concurrent use is generally considered safe. However, it is always advisable to consult with a healthcare provider before starting any new medication regimen, especially if you have underlying health conditions or are taking other medications.
2. If I want to stop taking Tadalafil, should I taper off or stop abruptly?
You can stop taking Tadalafil abruptly without the need for tapering. Tadalafil has a relatively long half-life, which means it stays in the body for a while after the last dose. Therefore, if you decide to discontinue its use, you may still experience its effects for a short period. However, if you have been using it for a long time and are concerned about any potential withdrawal effects or changes in your erectile function, it might be beneficial to discuss your plan with your healthcare provider. They can provide personalized advice based on your health status and treatment goals.
3. How long should I take Tadalafil before considering stopping?
The duration for which you should take Tadalafil largely depends on your individual needs and the underlying reason for its use. If Tadalafil is being used to manage erectile dysfunction, it can be taken as needed or on a daily basis, depending on your doctor's recommendations. If you find that your erectile function has improved and you no longer require the medication, you can consider stopping it. Typically, if you are using Tadalafil for erectile dysfunction, it is common to evaluate its effectiveness after a few months of consistent use. If you experience satisfactory results and feel confident in your erectile function, you may discuss with your doctor the possibility of discontinuing the medication.
In conclusion, the combination of Tadalafil and Finasteride is generally safe for long-term use, and you can stop Tadalafil without tapering. The decision to continue or discontinue should be based on your personal health goals and in consultation with your healthcare provider. Regular follow-ups are essential to monitor any side effects and to ensure that both medications are effectively addressing your health concerns. Always prioritize open communication with your healthcare provider regarding any changes in your medication regimen or health status.
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