Salivary Gland Scintigraphy Results and Functionality - Nuclear Medicine

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Report results of salivary gland scintigraphy?


Hello, Director.
Thank you for your previous response.
I forgot to attach my report content last time.
Below is my report, and I would like to ask about the functional status of my salivary glands and other glands.
Is there significant damage from autoantibodies, or is it manageable? Thank you! I apologize for the inconvenience.
Imaging findings: Tc99m 04- salivary scintigraphy: After intravenous injection of pertechnetate (6 mCi), serial dynamic images and an analytic functional curve (TOC) were acquired.
The imaging findings are as follows:
1.
Heterogeneous pertechnetate avid distribution in the bilateral parotid lobes with mild shrinkage (PsU R: 7.8; L: 8.7; PdU R: 9.0; L: 8.4); heterogeneously borderline dysfunctional excretory response to citric acid (PsE R: 63%; L: 65%; PdE R: 67%; L: 61%); faint distal Stenson's ductal stasis.
2.
Heterogeneously faint pertechnetate avid distribution in the bilateral submandibular glands (SmU R: 5.8; L: 6.8); borderline function of excretory response to citric acid (SmE R: 47%; L: 50%); heterogeneously reduced oral secretion.
3.
Heterogeneously mild reduced pertechnetate avidity in a smaller thyroid.
4.
Heterogeneously mild intense pertechnetate avid distribution in the nasal cavity and ethmoid sinus; heterogeneously mild hyperemia in the maxillary sinus and orbital cavity; faint falx.
5.
Heterogeneously compensatory parotid function and subtle submandibular uptake dysfunction.
Impression:
1.
Compensatory parotid function; please correlate with clinical findings.
2.
Mild rhinitis and sinusitis.

Ray, 30~39 year old female. Ask Date: 2024/07/17

Dr. Zheng Xiaoyi reply Nuclear Medicine


Hello Mr.
Ray: Based on this report, there is a slight decrease in salivary gland function.
However, as mentioned last time, assessing the condition cannot rely solely on a single test; it is essential to consider other clinical data for a comprehensive evaluation.
If you have any questions about the report, it is advisable to discuss them with your attending physician.

Reply Date: 2024/07/17

More Info


Salivary gland scintigraphy is a valuable imaging technique used to assess the functionality of the salivary glands, particularly in the context of conditions such as Sjögren's syndrome, which is an autoimmune disorder that can lead to dry mouth and eyes due to the destruction of exocrine glands. Your report indicates several key findings regarding the functionality of your salivary glands and other related structures.

1. Parotid Glands: The report shows a "heterogeneously pertechnetate avid distribution" in both parotid lobes, which suggests that there is some variability in how the radioactive tracer is taken up by the glands. The mild shrinkage of the parotid glands, along with a borderline dysfunctional excretory response to citric acid stimulation (with excretory responses of 63% and 65% for the right and left parotid glands, respectively), indicates that while the glands are still functioning, they are not performing optimally. The presence of "faintly distal Stenson's ductal stasis" suggests that there may be some obstruction or reduced flow in the duct that drains saliva from the parotid gland into the mouth.

2. Submandibular Glands: The scintigraphy shows a "heterogeneously faint pertechnetate avid distribution" in the bilateral submandibular glands, indicating reduced functionality. The excretory response to citric acid is also borderline (47% and 50% for the right and left submandibular glands), which further suggests that these glands are not functioning at full capacity. The report notes "heterogeneously reduced oral secretion," which aligns with the symptoms often seen in conditions like Sjögren's syndrome.

3. Thyroid Gland: The report mentions a "heterogeneously mild reduced pertechnetate avid smaller thyroid," which may indicate a reduction in thyroid function or size. This finding should be correlated with thyroid function tests to assess whether there is any clinical significance.

4. Nasal Cavity and Sinuses: The findings of mild hyperemia in the maxillary sinus and orbital cavity, along with mild rhinitis and sinusitis, suggest that there may be some inflammation present in these areas. This could be related to allergies, infections, or other inflammatory conditions.

5. Overall Impression: The report concludes with the impression of "compensatory parotid function," which indicates that while there may be some dysfunction, the parotid glands are compensating to maintain saliva production. The subtle dysfunction in the submandibular glands suggests that they are not adequately contributing to saliva production, which is often the case in autoimmune conditions.

In terms of the severity of damage from autoantibodies, the findings suggest that while there is some dysfunction, it may not be severe at this stage. However, the presence of borderline responses and reduced secretion indicates that monitoring and possibly further evaluation may be warranted. It is essential to correlate these findings with clinical symptoms and possibly other laboratory tests, such as autoantibody panels, to get a comprehensive understanding of your condition.

In conclusion, your scintigraphy results indicate some degree of dysfunction in both the parotid and submandibular glands, with compensatory mechanisms in place. It would be advisable to discuss these findings with your healthcare provider, who can provide further insights based on your clinical history and symptoms, and determine the best course of action for management and treatment.

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