Managing Elevated Liver Enzymes: Herbal vs. Western Medicine for Hepatitis B - Gastroenterology and Hepatology

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Liver function tests (LFTs)


Hello, doctor.
I have hepatitis B, and my liver function tests show elevated levels: GOT 147.1 and GPT 351.7.
What medication should I take? Traditional Chinese medicine or Western medicine? Also, what should I pay attention to? Thank you.

vince, 20~29 year old female. Ask Date: 2004/03/07

Dr. Liang Jiade reply Gastroenterology and Hepatology


First, check if the liver dysfunction is caused by hepatitis B before deciding on the treatment.
During liver dysfunction, it is important to rest as much as possible and avoid staying up late or consuming foods and medications that may affect the liver.

Reply Date: 2004/03/07

More Info


Managing elevated liver enzymes in patients with Hepatitis B can be a complex issue, and it is essential to approach it with a thorough understanding of both the medical condition and the available treatment options. Hepatitis B is a viral infection that affects the liver and can lead to serious complications, including liver cirrhosis and hepatocellular carcinoma. Elevated liver enzymes, such as GOT (AST) and GPT (ALT), indicate liver inflammation or damage, which is often a result of the viral infection.

In your case, with GOT at 147.1 and GPT at 351.7, it is crucial to first confirm that these abnormalities are indeed due to Hepatitis B. Other factors, such as alcohol consumption, fatty liver disease, or other viral infections, can also contribute to elevated liver enzymes. Therefore, a comprehensive evaluation by a healthcare professional is necessary to rule out other causes.

When it comes to treatment options, there are primarily two categories: Western medicine and herbal medicine. Western medicine includes antiviral medications such as lamivudine, entecavir, and tenofovir, which are specifically designed to suppress the Hepatitis B virus (HBV) and reduce liver inflammation. These medications have been shown to be effective in lowering liver enzyme levels and improving liver function over time. For patients with significant liver damage or high viral loads, these antiviral therapies are often the first line of treatment.

On the other hand, herbal medicine is sometimes considered by patients seeking alternative treatments. While some studies suggest that certain herbal remedies may have hepatoprotective effects or support liver health, the evidence is not as robust as that for antiviral medications. Additionally, the use of herbal supplements can sometimes lead to adverse effects or interactions with prescribed medications, which is why it is crucial to consult with a healthcare provider before starting any herbal treatment.

In your situation, it is advisable to prioritize Western medicine, particularly antiviral therapy, as it has a more established efficacy in managing Hepatitis B and its complications. Herbal remedies can be considered as complementary treatments, but they should not replace conventional antiviral therapy.
Moreover, lifestyle modifications are also essential in managing elevated liver enzymes and overall liver health. Here are some recommendations:
1. Avoid Alcohol: Alcohol can exacerbate liver damage, so it is crucial to abstain from alcohol consumption.

2. Healthy Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid processed foods, high-fat foods, and excessive sugar.

3. Regular Exercise: Engaging in regular physical activity can help maintain a healthy weight and improve liver function.

4. Stay Hydrated: Drink plenty of water to support liver detoxification processes.

5. Regular Monitoring: Keep up with regular follow-up appointments and blood tests to monitor liver function and viral load.

6. Avoid Certain Medications: Be cautious with over-the-counter medications and supplements that may affect liver function. Always consult your healthcare provider before taking any new medications.

In conclusion, managing elevated liver enzymes in Hepatitis B patients requires a comprehensive approach that includes antiviral therapy, lifestyle modifications, and regular monitoring. While herbal medicine may offer some benefits, it should not replace conventional treatments. Always consult with a healthcare provider to determine the best course of action tailored to your specific condition.

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