Lymph Node-Related Skin Issues: Causes and Concerns - Internal Medicine

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I would like to ask...
Recently, I have developed several bumps under my armpits, at the top of my inner thighs, and on the outer sides of my calves that resemble acne but are larger, painful, and have pus (all located in areas rich in lymph nodes).
A few years ago, I had a similar issue, and the doctor diagnosed it as folliculitis.
However, I am experiencing it again now.
I have been applying a corticosteroid ointment, which prevents it from worsening but does not improve it.
Additionally, I have many comedones on my legs and arms.
What could be the cause of this? I'm very worried...

mimi, 20~29 year old female. Ask Date: 2004/03/15

Dr. Chen Qingbin reply Internal Medicine


If folliculitis worsens and is accompanied by a bacterial infection, it may lead to the formation of an abscess and could even result in sepsis, so it should not be taken lightly.
It is best to promptly visit a hospital for evaluation and treatment by a dermatologist.

Reply Date: 2004/03/15

More Info


When it comes to skin issues related to lymph nodes, particularly in areas like the armpits, inner thighs, and outer calves, there are several potential causes and concerns that need to be addressed. Based on your description, it seems you are experiencing painful, pus-filled bumps in areas rich in lymphatic tissue, which could indicate a few different conditions.

Firstly, the presence of painful bumps that resemble larger acne lesions could suggest a condition known as folliculitis, which is an inflammation of the hair follicles. This can occur due to bacterial infections, often caused by Staphylococcus aureus, or even fungal infections. Given that you have a history of similar issues, it is possible that you are experiencing recurrent folliculitis. The fact that these lesions are painful and have pus suggests that there may be an active infection present.

Another possibility is that you are experiencing lymphadenopathy, which is the swelling of lymph nodes due to infection, inflammation, or other underlying conditions. When lymph nodes become inflamed, they can sometimes lead to localized skin changes, including the formation of bumps or lesions in the surrounding areas. This could be a response to an infection in the body, and the lymph nodes are working to filter out pathogens.

The use of topical corticosteroids may provide temporary relief by reducing inflammation, but they do not address the underlying cause of the infection or inflammation. If the lesions are not improving with topical treatments and are causing you concern, it is crucial to seek medical attention. A healthcare provider can perform a thorough examination, possibly including a culture of the pus to identify the causative organism, and recommend appropriate treatment, which may include antibiotics or antifungal medications.

Additionally, the presence of numerous comedones (the medical term for blackheads and whiteheads) on your legs and arms may indicate a condition known as acne vulgaris or a similar skin condition. Factors such as hormonal changes, diet, stress, and skin care products can contribute to the development of acne. It is essential to maintain a proper skincare routine, including gentle cleansing and non-comedogenic moisturizers, to help manage these symptoms.

In summary, the combination of painful, pus-filled bumps in lymphatic-rich areas and the presence of comedones suggests that you may be dealing with recurrent folliculitis or another skin infection. It is essential to consult with a healthcare provider for an accurate diagnosis and appropriate treatment plan. They may recommend a combination of topical and systemic therapies to address both the infection and the underlying skin condition. Additionally, maintaining good hygiene and being mindful of potential irritants in your environment can help prevent future outbreaks.

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