Male Pattern Baldness: Treatment Effects and Concerns - Dermatology

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Male pattern baldness


Hello Doctor, after being treated by you, I have noticed that my hairline has slightly receded over the past six years.
After using Minoxidil for 7 months along with a hair care solution, I have observed some improvement in the thinning hair at my forehead and hairline, with fine hairs starting to grow.
I found that the pharmacy sells two types of Minoxidil packaging, one in 1mg and the other in 5mg.
Is there any difference between the two? Additionally, I have noticed a significant decline in my sexual function.
Will continued use affect sperm quality, and is there a risk of having a child with birth defects? If I stop using it, will I be able to regain my previous sexual vitality? Thank you for your response.

pp, 30~39 year old female. Ask Date: 2001/02/07

Dr. Jin Lianchun reply Dermatology


Hello, sir:
1.
The dosage of Finasteride is a 1mg tablet, and the most suitable treatment for male pattern baldness is one tablet of 1mg per day.

2.
According to multiple research studies, it does not affect sperm quality, and men taking it will not produce malformed children.
However, it is absolutely prohibited for pregnant women to "touch" Finasteride, as it may cause developmental issues with the external genitalia of male fetuses.

3.
After discontinuing the medication, any side effects will definitely subside.
Wishing you a speedy recovery.

Reply Date: 2001/02/07

More Info


Male pattern baldness, also known as androgenetic alopecia, is a common condition that affects many men as they age. It is primarily driven by genetic factors and the influence of androgens, particularly dihydrotestosterone (DHT). DHT is a derivative of testosterone and is known to shrink hair follicles, leading to hair thinning and eventual hair loss. Treatments for male pattern baldness often aim to reduce DHT levels or promote hair growth.

One of the treatments available is finasteride, commonly known by its brand name Propecia or the generic name "柔沛" (Ruo Pei). This medication works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to DHT. By lowering DHT levels, finasteride can help slow down hair loss and even promote regrowth in some individuals. However, it is important to note that finasteride can have side effects, including sexual dysfunction, decreased libido, and potential impacts on sperm quality.

Regarding your question about the different dosages of finasteride (1mg vs. 5mg), the primary difference lies in the intended use. The 1mg dosage is typically prescribed for treating male pattern baldness, while the 5mg dosage is often used for benign prostatic hyperplasia (BPH). While both dosages can effectively lower DHT levels, the 1mg dose is generally sufficient for hair loss treatment and may have a lower risk of side effects.

As for your concerns about sexual function and sperm quality, it is well-documented that some men experience a decrease in libido and erectile dysfunction while taking finasteride. These side effects can be distressing and may lead to concerns about fertility and the potential for having children. While there is no conclusive evidence that finasteride causes birth defects or leads to the birth of malformed children, it is advisable for men taking finasteride to discontinue the medication at least a month before attempting to conceive, as the medication can remain in the system for some time.

If you decide to stop taking finasteride, many men report that their sexual function returns to baseline levels after discontinuation, although this can vary from person to person. It is essential to consult with your healthcare provider before making any changes to your medication regimen. They can provide guidance tailored to your specific situation and help monitor any potential side effects or concerns you may have.

In addition to pharmaceutical treatments, there are also natural remedies and lifestyle changes that may help manage hair loss. Saw palmetto is one such herbal supplement that some individuals use with the hope of reducing DHT levels. However, the evidence supporting its efficacy is mixed, and it may also carry the risk of side effects similar to those of finasteride.

In conclusion, male pattern baldness is a complex condition influenced by genetics and hormones. While treatments like finasteride can be effective, they come with potential side effects that should be carefully considered. If you have concerns about your treatment or its effects on your sexual health and fertility, it is crucial to have an open discussion with your healthcare provider to explore the best options for your situation.

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