Uncertain Rectal Tumors: Diagnosis Delays and Treatment Options - Surgery

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Suspicious rectal tumor


My brother developed hard lumps in his neck and shoulders this Qingming Festival, so he went to Chang Gung Memorial Hospital for examination.
After a thorough check-up of his entire body (including the organs and colon), no results were found, and the process took a month.
Eventually, he had to undergo a neck biopsy, which confirmed a malignant tumor with a marker level of 17.6.
However, the primary site of the metastasis could not be identified.
The doctor then started chemotherapy for his neck, and after six sessions, the marker level rose to 47, which is truly unbelievable.
He began radiation therapy yesterday.
The physician reviewed all the data and informed the family of a suspected rectal tumor.
May I ask if the physician delayed the treatment during the diagnosis? Given this condition, is the prognosis not optimistic, and is there a chance for a cure?

linda, 40~49 year old female. Ask Date: 2004/07/15

Dr. Huang Kaiwen reply Surgery


Approximately 10% of patients with metastatic malignant tumors in the cervical lymph nodes cannot be accurately diagnosed regarding the location of the primary tumor.
For these patients, treatment can only be based on the histopathological report and the cellular morphology for chemotherapy and radiotherapy.
You mentioned that your brother is suspected of having rectal cancer; a colonoscopy with biopsy should be performed to confirm the diagnosis.
If it is indeed rectal cancer with cervical lymph node metastasis, it would be classified as stage IV cancer, which has a poor prognosis.

Reply Date: 2004/07/15

More Info


Understanding uncertain rectal tumors, particularly in the context of delayed diagnosis and treatment options, is a complex issue that requires careful consideration of various factors, including the nature of the tumor, its staging, and the overall health of the patient.

In your brother's case, the timeline of events indicates a significant delay in diagnosis. Initially, he presented with hard lumps in the neck and shoulder, which prompted a series of investigations. However, it took a month of testing, including imaging and possibly blood tests, before a definitive diagnosis was made through a neck biopsy. The diagnosis of a malignant tumor with a high tumor marker level (17.6) suggests that the cancer is aggressive. The subsequent rise in tumor markers to 47 after six cycles of chemotherapy indicates that the treatment may not have been effective, or that the cancer is particularly resistant.

The identification of a suspected rectal tumor after these events raises several questions. Rectal tumors can vary widely in their characteristics, and the term "suspected rectal tumor" suggests that further investigation is necessary to confirm the diagnosis. The delay in identifying the primary tumor could potentially affect treatment outcomes. In general, the earlier a cancer is diagnosed and treated, the better the prognosis. Delays in diagnosis can lead to more advanced disease at the time of treatment, which can complicate management and reduce the chances of a cure.

Regarding the prognosis, if the rectal tumor is confirmed and is indeed a primary malignancy, the stage of the cancer will significantly influence treatment options and outcomes. Staging typically involves assessing the depth of invasion into the rectal wall, the involvement of nearby lymph nodes, and whether there is any distant metastasis. If the cancer has spread to lymph nodes or other organs, it may be classified as stage IV, which generally has a poorer prognosis.

In terms of treatment options, if the tumor is localized and has not spread significantly, surgical resection may be possible, potentially followed by adjuvant chemotherapy or radiation therapy to reduce the risk of recurrence. However, if the cancer is more advanced, treatment may focus on palliative care to manage symptoms and improve quality of life.

The question of whether there is a chance for a cure depends on the specific characteristics of the tumor, including its type, grade, and stage. For example, well-differentiated tumors may have a better prognosis than poorly differentiated ones. Additionally, the patient's overall health, response to previous treatments, and the presence of any comorbid conditions will also play a critical role in determining the likelihood of successful treatment.

In conclusion, the situation your brother is facing is indeed concerning, and the delays in diagnosis may have implications for his treatment options and prognosis. It is crucial for him to have open discussions with his healthcare team about the next steps, including potential imaging studies, biopsies, and treatment plans tailored to his specific condition. Seeking a second opinion or consulting with a specialist in oncology or colorectal surgery may also provide additional insights and options for managing his care.

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