Hepatitis B
I am a carrier of hepatitis B, but I have never experienced any symptoms of hepatitis.
I have always had a poor appearance and high levels of irritability.
In recent years, I have felt pressure in the area near my liver, and I feel discomfort when sleeping on my left side.
I started taking Lamivudine and immunomodulatory agents over three months ago.
Two weeks ago, my ALT was 68 and AST was 98.
However, in the past week, the pressure in the area near my liver has increased significantly, and it feels like bloating from within, especially after eating.
Aside from this, I have not noticed any other abnormalities.
Could this possibly indicate the beginning of cirrhosis? However, an ultrasound performed three months ago showed no issues.
Thank you for your response, doctor!
Jiànkāng rén, 20~29 year old female. Ask Date: 2000/11/16
Dr. Yang Guojun reply Internal Medicine
After taking Lamivudine for three months, if your GOT and GPT levels are still so high, please consider other causes of your hepatitis.
You should visit our clinic for further investigation, as you may not need to continue taking liver protection medication.
Reply Date: 2000/11/16
More Info
Hepatitis B is a viral infection that affects the liver and can lead to serious health issues, including liver cirrhosis and liver cancer. As a carrier of Hepatitis B, it is essential to monitor your liver health closely, especially if you are experiencing symptoms such as abdominal pressure or discomfort.
Symptoms of Hepatitis B
Many individuals with chronic Hepatitis B may not exhibit any symptoms, which can lead to a false sense of security. However, symptoms can manifest as the disease progresses. Common symptoms include:
- Fatigue
- Abdominal pain or discomfort, particularly in the liver area
- Jaundice (yellowing of the skin and eyes)
- Dark urine
- Pale stools
- Loss of appetite
- Nausea
In your case, the increasing pressure and discomfort in the liver area, especially after eating, could be indicative of liver inflammation or other complications. While your recent ALT and AST levels (ALT: 68, AST: 98) are elevated, they are not alarmingly high, but they do warrant further investigation, especially given your symptoms.
Treatment Options
You mentioned that you have been taking Lamivudine and an immune modulator. Lamivudine is an antiviral medication that can help control the replication of the Hepatitis B virus. However, it is important to note that resistance to Lamivudine can develop over time, which may necessitate a change in medication. Other antiviral options include Entecavir and Tenofovir, which are generally more effective and have a lower risk of resistance.
Concerns About Liver Health
The pressure you are feeling in your abdomen could be due to several factors, including liver inflammation, fatty liver disease, or even the early stages of liver cirrhosis. While your recent ultrasound did not show any abnormalities, it is crucial to continue monitoring your liver health through regular check-ups and imaging studies.
Cirrhosis typically develops over many years and is often the result of chronic liver inflammation. Symptoms of cirrhosis may not appear until significant damage has occurred. If you are concerned about the possibility of cirrhosis, it is advisable to discuss this with your healthcare provider, who may recommend additional tests such as a liver biopsy or elastography to assess liver stiffness.
Lifestyle Considerations
In addition to medication, lifestyle changes can significantly impact liver health. Here are some recommendations:
1. Diet: Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid high-fat, high-sugar, and processed foods.
2. Alcohol: Avoid alcohol consumption, as it can exacerbate liver damage.
3. Regular Exercise: Engage in regular physical activity to maintain a healthy weight and reduce liver fat.
4. Regular Monitoring: Keep up with regular blood tests to monitor liver function and viral load, as well as imaging studies to assess liver structure.
5. Avoid Self-Medication: Be cautious with over-the-counter medications and supplements, as some can be harmful to the liver.
Conclusion
While your symptoms may not directly indicate cirrhosis, they should not be ignored. It is essential to maintain open communication with your healthcare provider and report any changes in your condition. Regular monitoring and adherence to treatment can help manage Hepatitis B effectively and prevent complications. If your symptoms persist or worsen, further evaluation may be necessary to ensure your liver health is not at risk.
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