Duodenal Ulcers: Symptoms, Diagnosis, and Lifestyle Adjustments - Internal Medicine

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Duodenal ulcer with bulb deformity?


Hello! I am a working professional who spends most of my time sitting in the office.
I have low physical activity, and my Hepatitis B surface antigen is positive, while the e antigen is negative.
My weight and height are 70 kg and 173 cm, respectively.
I smoke half a pack of cigarettes per day and experience intermittent mild gastric discomfort every year, which resolves after taking antacids for 1-2 weeks before bedtime.
Eight months ago, I began experiencing postprandial diarrhea and frequent flatulence.
After undergoing an ultrasound at the hospital, the results indicated mild fatty liver, slightly elevated Helicobacter pylori (38.13 U/ml), and signs of intestinal dysmotility.
After three months of continuous medication prescribed by my doctor, my postprandial diarrhea has improved.
However, in the last two months, I have experienced some mild constipation.
Recently, my company conducted a health check, and various tests, including gastrointestinal and chest-abdomen X-rays, revealed chronic duodenal ulcers with bulb deformity and a slightly elevated arteriosclerosis index (4.9), mild liver function abnormalities (SGOT 26 U/L, SGPT 47 U/L), and slightly elevated creatinine levels (1.5 mg/dl).
1.
What do the above symptoms and test results signify clinically, and what lifestyle adjustments should I make?
2.
What is the relationship between Hepatitis B surface antigen and Hepatitis B e antigen? How can one determine if they have recovered from a Hepatitis B infection or if they have become a carrier?
3.
What is the clinical significance of the Helicobacter pylori index?
Thank you!

Hula, 40~49 year old female. Ask Date: 2000/11/16

Dr. Chen Shidian reply Internal Medicine


Hello: 1.
Fatty liver can lead to a slight increase in liver function tests; please exercise more.
2.
Chronic infection with Helicobacter pylori can cause gastritis and duodenal ulcers (recurrent ulcers may lead to deformation of the bulb).
3.
Elevated atherosclerosis index; please quit smoking, exercise more, and monitor blood lipids.
4.
The presence of surface antigens indicates a carrier of hepatitis B.
Wishing you safety.

Reply Date: 2000/11/16

More Info


Understanding duodenal ulcers involves recognizing their symptoms, diagnosis, and necessary lifestyle adjustments. Duodenal ulcers are a type of peptic ulcer that occurs in the lining of the duodenum, the first part of the small intestine. They can cause a range of symptoms and may be influenced by various factors, including diet, stress, and underlying health conditions.


Symptoms and Diagnosis
Common symptoms of duodenal ulcers include:
1. Abdominal Pain: This is often described as a burning sensation in the upper abdomen, which may improve with eating or taking antacids but can return a few hours later.

2. Nausea and Vomiting: Some patients may experience nausea, and in severe cases, vomiting may occur.

3. Bloating and Gas: Many individuals report feeling bloated or experiencing excessive gas.

4. Changes in Appetite: Some may have a decreased appetite due to discomfort after eating.

5. Weight Loss: Unintentional weight loss can occur if eating becomes painful.

Diagnosis typically involves a combination of medical history, physical examination, and diagnostic tests such as endoscopy, where a camera is used to visualize the ulcer, and tests for Helicobacter pylori (H. pylori), a common cause of ulcers.


Lifestyle Adjustments
Given your situation as a working professional with a sedentary lifestyle, here are some lifestyle adjustments you can consider:
1. Dietary Changes: Avoid spicy, acidic, or fried foods that can irritate the stomach lining. Instead, focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Eating smaller, more frequent meals can also help manage symptoms.


2. Hydration: Ensure you are drinking enough water throughout the day. Staying hydrated can aid digestion and overall health.

3. Limit Alcohol and Caffeine: Both can increase stomach acid and irritate the lining of the stomach and intestines. Reducing or eliminating these substances may help alleviate symptoms.

4. Quit Smoking: Smoking can interfere with the production of bicarbonate, which helps neutralize stomach acid, and can delay healing of ulcers.

5. Stress Management: Since stress can exacerbate ulcer symptoms, consider incorporating stress-reducing activities into your routine, such as yoga, meditation, or regular exercise.

6. Regular Exercise: Aim for at least 30 minutes of moderate exercise most days of the week. This can improve digestion and overall health.


Understanding Hepatitis B and H. pylori
1. Hepatitis B Surface Antigen and E Antigen: The presence of the Hepatitis B surface antigen (HBsAg) indicates an active infection. The e antigen (HBeAg) indicates high levels of viral replication and infectivity. If you test positive for HBsAg but negative for HBeAg, it may suggest a chronic infection with lower infectivity. To determine if you have cleared the infection or are a carrier, additional tests such as anti-HBs (antibody to HBsAg) and anti-HBe (antibody to HBeAg) are necessary.

2. H. pylori Significance: A high level of H. pylori can indicate an active infection, which is a significant risk factor for developing peptic ulcers. Treatment typically involves a combination of antibiotics and acid-reducing medications to eradicate the bacteria and promote healing.


Conclusion
In summary, managing duodenal ulcers involves understanding the symptoms and making necessary lifestyle adjustments. Regular follow-ups with your healthcare provider are essential to monitor your condition, especially considering your history of hepatitis B and the presence of H. pylori. By adopting a healthier lifestyle and adhering to your treatment plan, you can significantly improve your quality of life and reduce the risk of complications associated with duodenal ulcers.

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