Are There Side Effects of Long-Term Use of GOWELL Stomach Pills? - Pharmacology

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GOWELL Stomach Tablets - Are there any side effects from long-term use?


GOWELL gastric tablets - Are there any side effects from long-term use? The attending physician recommends taking it before meals or on an empty stomach (the patient had a duodenal ulcer 4.5 years ago and has recently been experiencing recurrent abdominal pain, with nausea occurring easily in the morning and at night).
Is this medication regimen correct?

pauline, 30~39 year old female. Ask Date: 2004/07/28

Dr. Wu Huiling reply Pharmacology


Hello Pauline! GOWELL gastric tablets are a type of antacid, containing a combination of aluminum and magnesium compounds.
Aluminum-based antacids can cause constipation, while magnesium-based antacids may lead to diarrhea; therefore, most products on the market are mixed compounds of magnesium and aluminum salts.
They can produce an acid-base neutralization effect, alleviating gastric discomfort and pain, and are classified as anti-ulcer medications.
When taken on an empty stomach, the effect of neutralizing gastric acid lasts for about half an hour; if taken one hour after a meal, the effect can last for approximately three hours.
Therefore, for optimal results, antacids are typically taken one hour and three hours after meals, as well as before bedtime.
Antacids can be used to relieve symptoms of excessive gastric acid secretion associated with peptic ulcers and gastroesophageal reflux, but they often need to be taken in large quantities, sometimes up to seven times a day, to achieve therapeutic effects.
If excessive gastric acid secretion is caused by a disease or medication, taking antacids can help neutralize the excess acid and alleviate gastric discomfort.

Reply Date: 2004/07/28

More Info


GOWELL Stomach Pills, which are a type of antacid containing a combination of aluminum and magnesium, are commonly used to alleviate symptoms associated with excess stomach acid, such as heartburn and indigestion. While they can be effective in providing relief, long-term use of these medications may lead to certain side effects and considerations that should be taken into account.

One of the primary concerns with long-term use of antacids like GOWELL is the potential for gastrointestinal side effects. Aluminum-based antacids can cause constipation, while magnesium-based antacids may lead to diarrhea. The combination of these two ingredients is designed to balance these effects, but individual responses can vary. Therefore, if you experience persistent gastrointestinal symptoms, it is essential to consult with your healthcare provider.

Regarding the recommended usage of GOWELL, taking it before meals or on an empty stomach is generally appropriate for immediate relief of symptoms. However, it is important to note that the effectiveness of antacids is time-sensitive. When taken on an empty stomach, the neutralizing effect on stomach acid lasts for a shorter duration—approximately 30 minutes. Conversely, taking the medication after meals can prolong its effectiveness, as it can neutralize the acid produced during digestion for a longer period, typically around three hours. For optimal results, many healthcare professionals recommend taking antacids one hour after meals and before bedtime.

Given your history of duodenal ulcers and recent symptoms of recurrent abdominal pain and nausea, it is crucial to monitor your condition closely. While GOWELL can provide symptomatic relief, it does not address the underlying causes of these symptoms. If you find that your symptoms persist or worsen, it is advisable to seek further evaluation from your healthcare provider. They may consider additional diagnostic tests or alternative treatments, such as proton pump inhibitors (PPIs) or H2 blockers, which can provide more sustained acid suppression and may be more appropriate for managing conditions like gastroesophageal reflux disease (GERD) or peptic ulcers.

Moreover, long-term use of antacids, especially those containing aluminum, can lead to other complications, such as electrolyte imbalances or even aluminum toxicity in rare cases. Therefore, it is essential to use these medications judiciously and under the guidance of a healthcare professional.

In summary, while GOWELL Stomach Pills can be effective for short-term relief of acid-related symptoms, long-term use should be approached with caution due to potential side effects. The recommended method of taking the medication before meals or on an empty stomach is appropriate, but for sustained relief, consider taking it after meals. Always consult with your healthcare provider for personalized advice and to explore other treatment options if your symptoms persist. Regular follow-up is essential to ensure that your treatment plan remains effective and safe.

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