The effects of iodine-131 radiation on children?
I am a patient with papillary thyroid carcinoma.
I received my first dose of iodine-131 treatment at 30 millicuries.
Due to certain factors, I came into contact with my young children five days after taking iodine-131.
I am concerned whether this could pose a risk to their future development or affect their physiological functions.
Are there any remedial measures? For example, should I consider regular thyroid checks for my children in the future? I would greatly appreciate your response, thank you.
Ms. Chen, 30~39 year old female. Ask Date: 2004/08/27
Dr. Chen Sirong reply Oncology
Hello: The primary treatment for thyroid cancer should be surgical resection.
For residual thyroid tissue that cannot be completely removed or metastatic lesions that cannot be treated surgically, I-131 therapy is required.
The principle of this treatment is that well-differentiated thyroid follicular and papillary carcinoma tissues have the ability to accumulate I-131.
After administering a large dose of I-131, the cancerous tissue and residual thyroid are sufficiently irradiated by beta particles, leading to destruction.
Currently, I-131 therapy can be administered as a single high-dose or multiple low-dose regimen (with each dose being less than 30 mCi).
According to current regulations, doses greater than 30 mCi require hospitalization and isolation; therefore, hospitals without isolation wards typically implement the multiple low-dose method.
Since approximately 76% of I-131 activity is excreted through urine, sweat, and saliva within 24 hours after administration, and the physical half-life of I-131 is 8 days, in the case of Ms.
Chen, the residual dose in her body on the fifth day should be less than 10%.
To minimize radiation exposure, the principles of radiation protection (ALARA: As Low As Reasonably Achievable) should be applied, which include reducing time and increasing distance to mitigate the probabilistic harm from radiation.
Regarding Ms.
Chen's contact with young children at home, it is likely that the contact was not prolonged (all day) or at a short distance (such as sleeping together), so there should be no significant radiation effects on the children.
There is no need for excessive concern.
Based on personal experience, as long as there is no contamination from excreta leading to internal radiation exposure (due to ingestion or inhalation of I-131), the radiation harm from I-131 therapy to others nearby is extremely minimal.
Please rest assured.
Sincerely, Dr.
Hsu Chung-Yuan, Radiology.
Reply Date: 2004/08/27
More Info
The use of Iodine-131 (I-131) for the treatment of thyroid cancer, particularly differentiated thyroid cancers like papillary thyroid carcinoma, is a well-established practice. I-131 works by selectively targeting thyroid tissue, including cancerous cells, due to their ability to absorb iodine. While this treatment is effective, it does raise concerns about radiation exposure, especially when it comes to children who may be in close contact with the patient shortly after treatment.
In your case, you received a dose of 30 mCi of I-131 and had contact with children five days post-treatment. It’s important to understand how I-131 behaves in the body and the potential risks associated with radiation exposure to others, particularly children.
Radiation Exposure and Its Effects
I-131 has a physical half-life of about 8 days, meaning that the radioactivity decreases significantly over time. By the fifth day after treatment, approximately 76% of the I-131 would have been eliminated from your body through urine, sweat, and saliva. The remaining activity would be considerably low, likely less than 10% of the original dose. This reduction in radioactivity significantly lowers the risk of radiation exposure to those around you, including children.
The primary concern with radiation exposure is the potential for long-term effects, including an increased risk of cancer. However, the risk is generally considered to be very low, especially when the exposure is minimal and occurs over a short duration. In your situation, the brief contact with children, assuming it was not prolonged or intimate (like sleeping together), is unlikely to pose a significant risk to their health or development.
Recommendations and Precautionary Measures
1. Minimize Close Contact: While the risk is low, it is advisable to minimize close contact with children for a few days following treatment. This includes avoiding situations where you might share bodily fluids, such as kissing or sleeping in close proximity.
2. Hygiene Practices: Maintain good hygiene practices, such as washing hands frequently and using separate utensils and towels, to further reduce any potential risk.
3. Monitoring Children’s Health: While routine thyroid checks for children are not typically necessary unless there are specific concerns, it may be prudent to discuss with your pediatrician the possibility of monitoring their thyroid function if there are any unusual symptoms or concerns in the future.
4. Education and Awareness: Educate yourself and your family about the effects of radiation and the importance of following medical advice regarding treatment and post-treatment care.
5. Consult Healthcare Providers: If you have ongoing concerns, it’s essential to communicate with your healthcare provider. They can provide personalized advice based on your specific situation and the latest medical guidelines.
Conclusion
In summary, while I-131 treatment does involve radiation, the risk to children from brief contact after treatment is minimal, especially after several days have passed. The body’s natural elimination processes significantly reduce the radioactive material present. Regular monitoring of children's health, particularly their thyroid function, can be part of a proactive approach, but it is not typically necessary unless there are specific concerns. Always consult with your healthcare provider for tailored advice and reassurance regarding your situation.
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