Hidden Blood in Urine: Causes and Concerns - Urology

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Hematuria


There are no physical discomforts, but a urinalysis showed occult blood (not visible to the naked eye), and ultrasound examinations are normal.
What could be the issue? Is it possible that this is bladder cancer?

c.c., 50~59 year old female. Ask Date: 2004/09/25

Dr. Lai Ronghao reply Urology


Hello, the causes of hematuria can exceed one hundred, including inflammation, infection, stones, tumors, and coagulopathy.
Therefore, if the examination results are normal, it is best to have regular follow-up checks.
This is a response from Dr.
Lai Rong-Hao, attending physician of the Urology Department at Hsinchu Hospital, Department of Health, Executive Yuan.

Reply Date: 2004/09/25

More Info


When it comes to the presence of hidden blood in urine, also known as "urine occult blood," it can be a concerning finding, especially when no other symptoms are present. The causes of occult blood in urine can vary widely, and while it is understandable to worry about serious conditions such as bladder cancer, it is important to consider a range of potential explanations.

First, it is essential to understand what "occult blood" means. This term refers to blood in the urine that is not visible to the naked eye but can be detected through laboratory tests. The sensitivity of these tests is quite high, but they can also yield false positives due to various factors, including menstruation, urinary tract infections (UTIs), vigorous exercise, or even certain medications. Therefore, a positive test for occult blood does not automatically indicate a serious condition.

In your case, since you mentioned that you have no other symptoms and that ultrasound examinations have returned normal results, it is crucial to consider other benign causes of occult blood. Some common reasons include:
1. Urinary Tract Infections (UTIs): Even if you do not have typical symptoms like burning during urination or frequent urination, a UTI can still cause blood to appear in the urine.

2. Kidney Stones: Small stones can irritate the urinary tract, leading to bleeding. Even if imaging studies did not show stones, they can sometimes be missed, especially if they are very small.

3. Benign Prostatic Hyperplasia (BPH): In men, an enlarged prostate can lead to blood in the urine, particularly in older adults.

4. Vigorous Exercise: Strenuous physical activity can sometimes lead to a condition known as "exercise-induced hematuria," where blood appears in the urine after intense workouts.

5. Medications: Certain medications, such as anticoagulants or nonsteroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding.

6. Glomerular Disease: Conditions affecting the kidneys, such as glomerulonephritis, can lead to blood in the urine.

7. Trauma: Any recent injury to the kidneys or urinary tract can also result in bleeding.

While bladder cancer is a possibility, especially in individuals over 40 or those with risk factors such as smoking or exposure to certain chemicals, it is less common than the aforementioned causes. If you have not experienced any weight loss, changes in urination patterns, or other systemic symptoms, the likelihood of cancer being the cause is lower.

Given the normal ultrasound results and the absence of other symptoms, it may be advisable to follow up with your healthcare provider for further evaluation. This could include:
- Repeat Urinalysis: To check for persistent occult blood and to perform a microscopic examination to assess for red blood cells and other abnormalities.


- Cystoscopy: A procedure where a thin tube with a camera is inserted into the bladder to directly visualize the bladder lining and rule out any abnormalities.

- CT Urography: A more detailed imaging study that can help identify issues in the urinary tract that may not be visible on standard ultrasound.

In conclusion, while the presence of occult blood in urine can be alarming, it is essential to approach the situation with a comprehensive understanding of potential causes. Regular follow-up with your healthcare provider and further diagnostic testing can help clarify the situation and ensure that any serious conditions are ruled out. Always remember that early detection and intervention are key to managing any health concerns effectively.

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