Why Does My Prescription Increase After Pupil Dilation? - Ophthalmology

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Why does the prescription increase after dilation?


Dear Dr.
Wang, I am an ophthalmic assistant from southern Taiwan.
Recently, I have noticed that some patients experience an increase in their refractive error after instilling mydriatic drops.
For example, a patient with a pre-dilation myopia of -5.00 diopters may have a post-dilation measurement of -6.50 or -7.00 diopters.
I am still uncertain about this issue and would appreciate your guidance on the correct explanation.
Thank you!

Cai Xiansheng, 20~29 year old female. Ask Date: 2004/10/31

Dr. Wang Zhangji reply Ophthalmology


Hello, I occasionally encounter similar situations, but it happens very rarely.
I'm not sure if you've noticed, but sometimes the astigmatism measurements before and after dilation can differ.
It is possible that the machine has converted the astigmatism measurement into myopia measurements, or it could be that the pre-dilation measurement was inaccurate.
It is best to conduct multiple measurements over a long period for more accurate results.
Sincerely, Dr.
Wang Zhang-ji, Ophthalmology.

Reply Date: 2004/10/31

More Info


When patients experience an increase in their prescription after pupil dilation, it can be attributed to several physiological and optical factors related to how the eye responds to the dilation process. Pupil dilation is typically achieved through the use of mydriatic agents, which relax the muscles of the iris, allowing the pupil to widen. This process is essential for a comprehensive eye examination, as it provides a better view of the retina and other internal structures of the eye. However, it can also affect the measurement of refractive error, leading to changes in the prescription.

One primary reason for the observed increase in myopia (nearsightedness) after dilation is the change in the eye's accommodation. Accommodation is the eye's ability to change its focus from distant to near objects, which is primarily controlled by the ciliary muscle. When mydriatic agents are administered, they paralyze the ciliary muscle, inhibiting its ability to contract. As a result, the eye may not be able to focus properly on near objects during the examination, leading to a miscalculation of the refractive error.

In a non-dilated state, the eye can accommodate for near vision, which may mask the true level of myopia. However, once the pupil is dilated and accommodation is disrupted, the full extent of the refractive error becomes apparent. This can lead to a higher measurement of myopia than what was recorded prior to dilation. For example, a patient who has a refractive error of -5.00 diopters may appear to have a prescription of -6.50 or -7.00 diopters after dilation due to the inability to accommodate.

Another factor to consider is the effect of the increased pupil size on the depth of focus. A larger pupil allows more light to enter the eye, but it also reduces the depth of field. This means that the eye may not focus as well on objects at various distances, which can further complicate the measurement of refractive error during the examination.

Additionally, the optical quality of the eye can change with dilation. The increased pupil size can lead to more aberrations, which can affect the clarity of the image formed on the retina. These optical aberrations can also contribute to the perception of increased myopia.

It is also essential to consider the timing of the refraction measurement. If the refraction is performed too soon after dilation, the effects of the mydriatic agents may still be influencing the eye's ability to focus. It is often recommended to wait for a sufficient period after dilation before performing the refraction to ensure that the measurements reflect the true refractive state of the eye.

In conclusion, the increase in prescription after pupil dilation can be attributed to the paralysis of accommodation, changes in optical quality, and the timing of the refraction measurement. It is crucial for eye care professionals to be aware of these factors when interpreting refraction results after dilation. If patients experience significant changes in their prescription, it may be beneficial to reassess their refractive error after allowing adequate time for the effects of the mydriatic agents to wear off. This approach can help ensure that the prescription accurately reflects the patient's visual needs.

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