Exploring Steroid Injections for Recurrent Urethral Stricture Treatment - Urology

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Steroid injection


Hello Dr.
Lin, I previously consulted you about the possibility of using steroid injections to suppress scar tissue formation in cases of recurrent urethral stricture caused by trauma.
I would like to ask if there are any doctors or hospitals in Taiwan that have performed similar treatments.
I recently underwent a second self-funded stent placement, but it displaced due to poor adhesion, and the same stricture site has recurred.
After two direct visual excisions of the hyperplastic tissue, I am at my wit's end, as my current job is also at risk.
I hope you can provide me with a referral to help restore my confidence.
Thank you.

Marco, 20~29 year old female. Ask Date: 2004/11/09

Dr. Lin Hexing reply Urology


I'm sorry, but I'm not aware of where such treatment is available.
You might want to inquire with the Urology Department at Linkou Chang Gung Memorial Hospital!

Reply Date: 2004/11/09

More Info


Exploring the use of steroid injections for recurrent urethral stricture treatment is a pertinent topic, especially for patients who have experienced multiple interventions with limited success. Urethral strictures can be particularly challenging to manage, and the recurrence of these strictures can significantly impact a patient's quality of life, as you've described.
Steroid injections are indeed being explored as a potential adjunctive treatment for urethral strictures. The rationale behind using steroids is primarily to reduce inflammation and inhibit scar tissue formation, which is a common issue following surgical interventions for strictures. Scar tissue can lead to the recurrence of strictures, and by using steroids, there is hope that the healing process can be modulated to minimize this risk.

In terms of the effectiveness of steroid injections, some studies have shown promising results, indicating that they may help reduce the recurrence rates of strictures when used in conjunction with other treatments, such as dilation or urethrotomy. However, the evidence is still emerging, and more research is needed to establish standardized protocols regarding dosage, frequency, and the specific types of steroids that may be most effective.

Regarding your inquiry about specific doctors or hospitals in Taiwan that perform this type of treatment, it would be best to consult with urologists who specialize in reconstructive urology or those who have experience with urethral strictures. They may be more familiar with the latest treatment modalities, including steroid injections, and can provide personalized recommendations based on your medical history and current condition.
It is also important to discuss your previous experiences with stenting and the complications you've faced, as this information will be crucial for any healthcare provider to understand your case fully. They may suggest a multidisciplinary approach, involving urologists, pain management specialists, and possibly physical therapists, to address both the physical and emotional aspects of your condition.

In addition to steroid injections, other treatment options for recurrent urethral strictures include:
1. Dilation: This is a non-surgical procedure that involves gradually widening the urethra to relieve the stricture. It can be performed under local anesthesia and may need to be repeated periodically.

2. Urethrotomy: This surgical procedure involves cutting the stricture to relieve the blockage. While effective, there is a risk of recurrence, which is why adjunctive treatments like steroid injections may be considered.

3. Urethral Reconstruction: In cases of severe or recurrent strictures, a more extensive surgical approach may be necessary, where the affected segment of the urethra is removed and reconstructed using tissue from another part of the body.

4. Tissue Engineering Approaches: Research is ongoing into the use of bioengineered tissues or grafts to replace or repair the damaged urethra, which may provide a more permanent solution.

5. Regular Follow-up: Regardless of the treatment chosen, regular follow-up with a urologist is essential to monitor for recurrence and manage any complications promptly.

In conclusion, while steroid injections may offer a potential avenue for managing recurrent urethral strictures, it is crucial to have a thorough discussion with a qualified urologist who can tailor a treatment plan to your specific needs. Your situation is understandably frustrating, but with the right medical support and interventions, there is hope for improvement. Don't hesitate to seek out specialists who are familiar with the latest advancements in urethral stricture management.

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