The development period of gastric cancer?
Dear Doctor: Recently, I read about a physician from National Taiwan University who was diagnosed with liver cancer and passed away within a brief period of 2 to 3 months.
Is it possible for all types of cancer to progress from zero to terminal stages, even leading to death, in such a short time? My father passed away from stomach cancer, and by the time it was discovered, he was already in stage IV.
I recall that about two years ago, he occasionally mentioned discomfort in his upper abdomen, which progressed from occasional pain to frequent and then continuous pain.
After undergoing a total gastrectomy, the doctors informed us that his abdominal cavity was filled with cancer cells.
In such a situation, could it also happen like that physician from National Taiwan University, where everything manifested in the last four months? I sincerely seek your clarification and am very grateful.
lee, 30~39 year old female. Ask Date: 2004/11/15
Dr. Chen Sirong reply Oncology
Hello: 1.
Normal gastric cells naturally undergo apoptosis and regeneration at fixed intervals, achieving homeostasis.
2.
During the process of cell regeneration, which involves gene replication and division, some genetic mutations may occur.
3.
A small number of cells with genetic mutations become immortal cells, which do not participate in the normal metabolic ecology and can develop into cancer cells.
4.
These cancer cells can be recognized and destroyed by immune cells, preventing the development of gastric cancer; however, if a single cancer cell gradually grows to about 1 centimeter, it can be detected by modern technology.
5.
Gastric cancer can invade blood vessels or lymphatic vessels, leading to metastasis in lymph nodes or spreading throughout the body, or it can penetrate the gastric wall and disseminate into the abdominal cavity.
6.
This process takes years, certainly not just four months.
Sincerely, Dr.
Chen Sih-Rong, Oncology.
Reply Date: 2004/11/15
More Info
Understanding the rapid progression of stomach cancer can be a complex and emotionally charged topic, especially for those who have experienced the loss of a loved one to this disease. Your inquiry touches upon a critical aspect of cancer biology and patient experiences, particularly regarding the speed at which certain cancers can progress from early detection to advanced stages.
Stomach cancer, or gastric cancer, can indeed exhibit a rapid progression in some cases. The timeline from initial symptoms to advanced disease can vary significantly among individuals. Factors influencing this progression include the type of cancer, its biological characteristics, the patient's overall health, and the presence of underlying conditions. In some instances, stomach cancer can be asymptomatic in its early stages, leading to late diagnoses when the disease has already advanced significantly.
The case you mentioned regarding a physician diagnosed with liver cancer progressing rapidly within 2 to 3 months is not uncommon. Certain aggressive types of cancer, such as pancreatic or liver cancer, can lead to rapid deterioration. However, it is essential to note that not all cancers behave in the same manner. For example, some stomach cancers may grow slowly and allow for more extended periods of treatment and management before reaching an advanced stage.
In your father's case, it appears that he experienced a gradual worsening of symptoms over approximately two years, which is more typical for many gastric cancer patients. Symptoms such as persistent abdominal discomfort, weight loss, and changes in appetite can indicate underlying issues that warrant further investigation. Unfortunately, by the time stomach cancer is diagnosed at an advanced stage (like stage IV), it often means that the cancer has spread beyond the stomach to other organs, making treatment more challenging.
The rapid progression you referenced can occur, but it is not the norm for all cancer types. Each patient's journey is unique, and the timeline can be influenced by various factors, including the cancer's histological type, the presence of metastases, and the patient's response to treatment. For instance, some patients may respond well to chemotherapy or targeted therapies, while others may not see significant benefits, leading to a more rapid decline in health.
In summary, while some cancers can progress rapidly, many factors contribute to the individual experience of cancer progression. It is crucial for patients and their families to maintain open communication with healthcare providers, who can offer insights into the specific type of cancer, its expected behavior, and the best management strategies. Regular monitoring and timely intervention can also play a significant role in improving outcomes and quality of life for cancer patients.
If you have further questions or need support, consider reaching out to healthcare professionals who specialize in oncology or palliative care. They can provide valuable information and resources to help navigate this challenging journey.
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