the Impact of Misdiagnosis in Mental Health Treatment - Psychiatry

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Director Tang: Hello, my brother has been experiencing some mental health issues due to work-related stress for the past 3-4 months.
A friend suggested that I take him to see a psychiatrist.
The psychiatrist at Zhongxing Hospital in Taipei prescribed him Zactin 20mg (to be taken once daily) for depression and Amprazo 0.5mg (to be taken three times daily) for anxiety.
However, after more than three months of taking these medications, there has been no significant improvement in his mental state; in fact, his mood has been increasingly low, and at times he even exhibits signs of dementia.
It seems that this situation cannot continue.
I would like to specifically ask you, Director Tang, based on your expertise and years of clinical experience, if the physician misdiagnosed my brother's condition and he has been taking medication for a long time, could this negatively impact his mental health? Seeing him in such pain, I hope you can help me and clarify my concerns.
Thank you.

Xiao Wen, 30~39 year old female. Ask Date: 2004/12/02

Dr. Tang Xinbei reply Psychiatry


Dear Xiao Wen,
It is truly touching to see your concern for your brother's illness.
Since I am not familiar with his condition and have not examined him, I cannot determine whether there is a possibility of misdiagnosis.
However, I prefer to trust the judgment and prescription of the psychiatrist at Chung Hsing Hospital.
After all, if the practitioner is a psychiatrist, they should have graduated from a medical school recognized by the Department of Health and completed at least three years of residency training in psychiatry at an accredited teaching hospital, as well as passed the Department of Health's certification examination for psychiatrists.
Based on the prescription provided by the doctor, it seems likely that your brother is suffering from depression combined with anxiety, which is why the physician prescribed antidepressants and anxiolytics.
Generally, patients with depression tend to respond to medication more slowly, often requiring two to four weeks to notice some effects, and in some cases, it may take three to six months for others to respond.
Currently, it appears that your brother's condition has not improved, which understandably causes you significant concern.
Since other mental health disorders can also present with symptoms of depression and anxiety in their early stages, or if your brother's constitution and condition are not responding clearly to the current medications, I recommend that you accompany him to a follow-up appointment as soon as possible to discuss his medication response with his attending physician.
That doctor can assess whether to continue with the current medications, make adjustments to the dosage, switch to different antidepressants, or consider other types of medications if your brother's condition has changed.
Wishing your brother safety and a speedy recovery!

Reply Date: 2004/12/02

More Info


Misdiagnosis in mental health treatment can have significant and detrimental effects on a patient's overall well-being. When a mental health condition is incorrectly identified, the prescribed treatment may not only be ineffective but could also exacerbate the patient's symptoms, leading to a decline in their mental health status. In your brother's case, the prescribed medications, Zactin (an antidepressant) and Amprazo (an anxiolytic), may not be addressing the underlying issues he is experiencing, especially if the diagnosis was inaccurate.

One of the primary concerns with misdiagnosis is that it can lead to a prolonged period of ineffective treatment. In your brother's situation, he has been on these medications for over three months without any noticeable improvement, and instead, his emotional state has worsened. This lack of response to treatment can lead to feelings of hopelessness and frustration, which may further contribute to his depressive symptoms. Additionally, the prolonged use of medications that are not suitable for his condition can result in unwanted side effects, including cognitive impairment, emotional blunting, or even the development of new symptoms.

Moreover, the medications prescribed may have their own side effects that could mimic or worsen existing symptoms. For instance, some antidepressants can lead to increased anxiety or agitation in certain individuals, while anxiolytics can cause sedation and cognitive dulling. If your brother is experiencing symptoms that resemble dementia, it is crucial to consider whether these symptoms are a result of the medications or if they stem from an underlying condition that has not been properly diagnosed.

It is also important to recognize that mental health conditions are often complex and multifaceted. Symptoms can overlap between different disorders, making accurate diagnosis challenging. For example, anxiety and depression frequently co-occur, and symptoms such as cognitive difficulties, memory issues, and emotional instability can be present in both conditions. If a healthcare provider does not take a comprehensive approach to diagnosis, they may overlook critical aspects of the patient's mental health, leading to misdiagnosis.

Given your brother's worsening condition, it would be advisable to seek a second opinion from another mental health professional. A thorough re-evaluation of his symptoms, medical history, and response to treatment is essential. This may involve a comprehensive assessment that includes psychological testing, a review of his medication regimen, and a discussion of any potential underlying issues that may not have been addressed.

In conclusion, misdiagnosis in mental health treatment can lead to a cycle of ineffective treatment, worsening symptoms, and potential cognitive decline. It is vital to ensure that your brother receives an accurate diagnosis and appropriate treatment tailored to his specific needs. Open communication with healthcare providers, advocating for a second opinion, and exploring alternative treatment options can help improve his mental health outcomes. Remember, mental health is a dynamic field, and finding the right treatment may take time and persistence.

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