Gallbladder Polyps: Risks, Diet, and Symptoms Explained - Gastroenterology and Hepatology

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Gallbladder polyp


Symptoms: Gallbladder polyp 0.4 cm; GPT 40, GOT 30; mild fatty liver, no hepatitis C, positive for hepatitis B antibodies; blood lipids and blood glucose are normal.
Duration: This was discovered during a hospital examination two days ago; an ultrasound six months ago showed no fatty liver or gallbladder polyps.
Additional information: What is the likelihood that the gallbladder polyp is malignant? I am considering taking fish oil to lower cholesterol; will this help the gallbladder polyp disappear, or should I avoid it? Why do I experience diarrhea after taking fish oil, and why is it oily?

popo, 20~29 year old female. Ask Date: 2004/12/23

Dr. Su Baojia reply Gastroenterology and Hepatology


The examination results indicate that liver function is within the normal range, and there is no evidence of hepatitis B or C.
The presence of hepatitis B antibodies suggests that there will be no future infection with the hepatitis B virus.
The ultrasound examination uses images reflected from the liver as a diagnostic reference, which may be influenced by the examiner's subjectivity or the ultrasound frequency and brightness, potentially leading to discrepancies such as the presence of mild fatty liver observed two days ago, despite no fatty liver being noted six months prior.

Gallbladder polyps are considered one of the risk factors for the development of gallbladder cancer.
Polyps larger than 1 cm have a limited but significant chance of becoming cancerous.
If a polyp exceeds 1 cm, the patient is over 50 years old, or there are three or more polyps, surgical removal is recommended.
Therefore, individuals with gallbladder polyps should undergo ultrasound follow-up every six months.

Taking fish oil will not cause polyps to disappear; fish oil is the fat found in fish, primarily composed of polyunsaturated fatty acids EPA and DHA.
Consuming large amounts is akin to ingesting oil, which can naturally lead to diarrhea and oily stools.

Reply Date: 2004/12/23

More Info


Gallbladder polyps are growths that protrude from the lining of the gallbladder. They are often discovered incidentally during imaging studies, such as ultrasounds, and can vary in size. In your case, a polyp measuring 0.4 cm was identified, which is relatively small. The majority of gallbladder polyps are benign, with a low risk of malignancy, especially when they are less than 1 cm in size. The risk of a polyp being cancerous increases significantly when it exceeds 1 cm, and even more so for larger polyps.

Regarding your liver function tests, your GPT (ALT) level is slightly elevated at 40, while your GOT (AST) is at 30. These values suggest mild liver dysfunction, which could be associated with your diagnosis of fatty liver. Fatty liver disease can be caused by various factors, including obesity, excessive alcohol consumption, and certain medications. Since you mentioned that you do not have hepatitis B or C, it is essential to focus on lifestyle changes to manage your liver health.

As for your question about diet, incorporating fish oil into your diet can have beneficial effects on cholesterol levels. Omega-3 fatty acids found in fish oil can help lower triglycerides and may improve overall heart health. However, it is important to note that fish oil can also cause gastrointestinal side effects, including diarrhea, particularly if taken in high doses. The oily consistency of fish oil can lead to fatty stools, which may explain why you are experiencing diarrhea that appears oily. If you find that fish oil consistently causes digestive issues, it may be worth considering alternative sources of omega-3 fatty acids, such as flaxseed oil or chia seeds, or discussing with your healthcare provider about adjusting the dosage.

In terms of managing gallbladder polyps, there is currently no evidence to suggest that dietary changes, including the consumption of fish oil, can cause polyps to disappear. However, maintaining a healthy diet low in saturated fats and high in fiber can support overall gallbladder and liver health. Foods rich in fruits, vegetables, whole grains, and lean proteins are beneficial. Additionally, avoiding processed foods, excessive sugar, and trans fats can help reduce the risk of gallbladder issues and support liver function.

If you are concerned about the gallbladder polyp or your liver function, it is advisable to follow up with your healthcare provider. They may recommend regular monitoring of the polyp through ultrasound examinations, especially if there are any changes in size or symptoms. If you experience any new symptoms, such as abdominal pain, jaundice, or changes in bowel habits, you should seek medical attention promptly.

In summary, while the risk of malignancy for a 0.4 cm gallbladder polyp is low, it is essential to monitor your liver health and consider dietary adjustments to support your overall well-being. If fish oil causes digestive discomfort, consult with your healthcare provider for alternative options and to ensure that your dietary choices align with your health goals.

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