Polycystic Ovary Syndrome (PCOS)
After undergoing examinations by Western medicine, I have been diagnosed with polycystic ovary syndrome (PCOS) and have many pimples on my face that are red, swollen, and painful, primarily concentrated on my chin and the sides of my cheeks.
I previously used Diane (Diane-35) for about a year with good results, but I am concerned about potential side effects.
Currently, I am receiving Traditional Chinese Medicine treatment to regulate my menstrual cycle, but the acne issue has not improved, which has greatly affected my confidence.
Could you please advise me on what medications a dermatologist might prescribe for treatment? What is their effectiveness, and are there any side effects? Thank you.
I'm sorry, 20~29 year old female. Ask Date: 2005/01/09
Dr. Jiang Zheen reply Dermatology
Hormonal acne generally requires hormonal treatment, and besides Diane, there are other types of hormonal therapies available.
Of course, they may have some side effects to varying degrees.
If hormonal treatment is not an option, one can also consider using oral retinoids, which do have some side effects, but they are usually not severe.
Wishing you peace and may God bless you.
Reply Date: 2005/01/09
More Info
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that can lead to various symptoms, including acne, particularly in areas such as the chin and cheeks. The acne associated with PCOS is often due to hormonal imbalances, specifically elevated levels of androgens (male hormones), which can increase sebum production and lead to clogged pores.
When it comes to treating acne related to PCOS, dermatologists typically have a range of effective options. One of the most commonly prescribed treatments is hormonal therapy, which can include oral contraceptives like Diane (ethinyl estradiol and cyproterone acetate). These medications work by regulating hormonal levels, thereby reducing androgen production and, consequently, acne. While Diane has shown effectiveness, it is essential to be aware of potential side effects, which may include nausea, weight gain, mood changes, and an increased risk of blood clots.
If you are concerned about the side effects of hormonal treatments, there are alternative options. For instance, oral retinoids, such as isotretinoin, are highly effective for severe acne but come with their own set of potential side effects, including dryness, photosensitivity, and, in rare cases, severe birth defects if taken during pregnancy. Therefore, effective contraception is crucial when using this medication.
Antibiotics, such as doxycycline, are also commonly prescribed for acne. They work by reducing inflammation and bacterial growth on the skin. However, long-term use can lead to antibiotic resistance, and side effects may include gastrointestinal upset and increased sensitivity to sunlight.
In addition to these systemic treatments, topical therapies can be beneficial. Topical retinoids (like tretinoin) help to unclog pores and reduce inflammation, while benzoyl peroxide can kill acne-causing bacteria. However, these treatments may cause skin irritation, especially when starting, so it's essential to introduce them gradually.
Another option is the use of anti-androgen medications, such as spironolactone, which can help reduce sebum production and improve acne. This medication can also have side effects, including menstrual irregularities and breast tenderness.
For those who prefer a more holistic approach, some individuals find success with lifestyle modifications, including weight management, dietary changes, and regular exercise, which can help regulate insulin levels and improve hormonal balance. Additionally, some studies suggest that supplements like inositol may help improve insulin sensitivity and hormonal balance in women with PCOS.
In summary, while there are various effective dermatological treatments for acne associated with PCOS, the choice of therapy should be tailored to the individual, considering both efficacy and potential side effects. It is crucial to work closely with both a dermatologist and an endocrinologist to develop a comprehensive treatment plan that addresses both the skin symptoms and the underlying hormonal issues. Regular follow-ups and adjustments to the treatment plan may be necessary to achieve the best results while minimizing side effects.
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