Guillain-Barré Syndrome: Impact on Children After Vaccination - Neurosurgery

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Guillain-Barré syndrome (acute inflammatory demyelinating polyneuropathy)


I would like to ask what Guillain-Barré syndrome (GBS) is, as my son, who is over one year old, developed Guillain-Barré syndrome (GBS) following the administration of a booster dose of the MMR vaccine.
His main symptom has been weakness in his limbs, which has led to flat feet due to walking on his toes.
After undergoing surgery at the age of six, he has experienced swaying while walking and runs in a manner similar to that of a child with polio.
He is now in the first grade, and his condition remains the same.
What kind of impact will this have on his physical development in the future? Additionally, since I am unsure whether to consult a neurologist or a neurosurgeon, if it is a matter for neurology, please refer me to another physician for assistance.
Thank you!

Lin, 30~39 year old female. Ask Date: 2005/03/06

Dr. Qiu Yushu reply Neurosurgery


Guillain-Barré Syndrome has caused weakness in the limbs since the age of one, and there are still difficulties in walking.
It is likely a sequela of nerve damage, which may be challenging to recover from.
It is advisable to first consult a neurologist to confirm the diagnosis, followed by rehabilitation therapy.

Reply Date: 2005/03/06

More Info


Guillain-Barré Syndrome (GBS) is a rare neurological disorder in which the body's immune system mistakenly attacks the peripheral nerves. This condition can lead to muscle weakness, paralysis, and sensory disturbances. While GBS can occur after infections, it has also been associated with vaccinations, although such occurrences are extremely rare. The exact mechanism by which vaccines may trigger GBS is not fully understood, but it is believed that the immune response to the vaccine may inadvertently target nerve tissues.

In your case, your son developed GBS following a vaccination, which is a concerning but rare complication. The symptoms you described, such as limb weakness and difficulties with walking, are common manifestations of GBS. The fact that he experiences flat feet and has difficulty running may indicate that he is dealing with residual effects from the nerve damage caused by the syndrome.
The prognosis for children with GBS can vary significantly. Some children recover completely, while others may experience long-term effects, including muscle weakness, coordination problems, or sensory issues. The recovery process can be slow and may require physical therapy to help regain strength and improve mobility. It is essential to monitor your son's progress and work closely with healthcare professionals to address any ongoing issues.

As for the impact on his future physical development, it is difficult to predict with certainty. Children who have experienced GBS may face challenges in physical activities, which can affect their confidence and participation in sports or other physical education. However, with appropriate rehabilitation and support, many children can lead active and fulfilling lives.
Regarding your question about whether to consult a neurologist or a neurosurgeon, it is advisable to start with a neurologist. A neurologist specializes in disorders of the nervous system and can provide a comprehensive evaluation of your son's condition. They can assess the extent of any nerve damage, recommend appropriate rehabilitation strategies, and monitor his progress over time. If surgical intervention is ever deemed necessary, the neurologist can refer you to a neurosurgeon.

In summary, Guillain-Barré Syndrome can have significant implications for children, particularly when it arises after vaccination. While the road to recovery may be challenging, early intervention and ongoing support can help your son manage his symptoms and improve his quality of life. It is crucial to maintain open communication with healthcare providers and to seek specialized care to address any concerns as they arise.

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