Why Does My Baby Keep Getting Oral Thrush? Recurrences - Internal Medicine

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Why do babies experience recurrent thrush?


Hello Doctor, I consulted you on February 25th regarding my concerns about my baby, who has just turned six months old.
Since birth, my baby has experienced oral thrush six times.
The attending physician recommended tests to check for any issues with the immune system.
The test results showed low neutrophils and high lymphocytes, but everything else was normal.
Dr.
Zhao responded that my baby should be considered normal.
I would like to ask Dr.
Zhao why my baby keeps experiencing recurrent oral thrush and whether it could affect their health.
P.S.
There should be no issues with oral hygiene.

Youying de mama, 30~39 year old female. Ask Date: 2005/03/10

Dr. Zhao Chongliang reply Internal Medicine


Oral thrush is a common condition in infants, partly due to their physiological leukopenia, which limits their ability to phagocytize fungi (Candida).
Additionally, infants who rely solely on breast milk or formula may have lower levels of vitamin B2 and zinc, making them less capable of resisting Candida growth.
At this stage, the oral microbiota in infants is also not fully developed, providing an opportunity for fungi to thrive in the oral cavity.

It is important to consider whether the infant is using inhaled or oral corticosteroids (such as those used by asthma patients), as these can impair the body's defense mechanisms and allow fungal invasion.
The use of antibiotics should also be noted, as it is common for infants with fever to be prescribed antibiotics, which can eliminate harmless oral flora and create an environment for fungi to proliferate.
Additionally, frequent drooling without regularly changing bibs can lead to fungal growth on saliva-saturated bibs, which can be transferred to the infant's mouth by hands.
If oral thrush does not affect the infant's appetite and resolves quickly, it indicates that the baby's immune system is functioning normally.
After the age of one, oral thrush should not be a recurring issue.
Treatment for oral thrush differs between adults and infants; adults may use corticosteroid ointments to expedite healing, but due to the infant's already compromised immunity, corticosteroid ointments should never be used.
Instead, antifungal powders or solutions should be employed to prevent recurrent thrush.

Reply Date: 2005/03/10

More Info


Oral thrush, also known as oropharyngeal candidiasis, is a common fungal infection in infants, primarily caused by the overgrowth of Candida species, particularly Candida albicans. This condition can be concerning for parents, especially when it recurs frequently, as in your baby's case. Understanding the underlying causes and management strategies is essential for addressing this issue effectively.


Why Does Oral Thrush Occur?
1. Immature Immune System: Infants, especially those under one year of age, have an immature immune system. This makes them more susceptible to infections, including fungal infections like thrush. The immune system is still developing its ability to regulate the growth of various microorganisms, including fungi.

2. Dietary Factors: Babies who are exclusively breastfed or formula-fed may have a different oral microbiome compared to older children or adults. The lack of diverse oral flora can allow Candida to proliferate. Additionally, if a baby is on antibiotics, it can disrupt the balance of normal flora in the mouth, leading to an overgrowth of Candida.

3. Oral Hygiene: While you mentioned that oral hygiene is not an issue, it’s important to ensure that feeding bottles, pacifiers, and any other items that come into contact with the baby’s mouth are kept clean. Fungal spores can thrive on these surfaces if they are not properly sanitized.

4. Saliva and Drooling: Excessive drooling, which is common in infants, can create a moist environment in the mouth that is conducive to fungal growth. If the drool-soaked bibs or clothing are not changed frequently, they can harbor Candida.

5. Underlying Health Issues: Although your baby’s immune system appears normal based on the tests, any underlying health issues that affect the immune response can predispose them to recurrent thrush. Conditions that lead to a decrease in immune function or changes in the oral environment can contribute to this problem.


Management and Prevention Strategies
1. Maintain Oral Hygiene: Regularly clean your baby’s mouth with a soft, damp cloth. If your baby has started eating solids, ensure that any food particles are cleaned from the mouth after meals.

2. Monitor Feeding Equipment: Sterilize bottles, nipples, and pacifiers regularly. Boiling them or using a dishwasher with a sterilizing cycle can help eliminate fungal spores.

3. Limit Sugar Intake: If your baby is consuming any solid foods, try to limit sugary foods, as sugar can promote the growth of Candida.

4. Consult a Pediatrician: If thrush persists, it’s crucial to consult your pediatrician or a pediatric infectious disease specialist. They may recommend antifungal medications, such as nystatin or fluconazole, to treat the infection effectively.

5. Check for Other Conditions: If your baby continues to experience recurrent thrush, further evaluation may be necessary to rule out any underlying conditions that could be affecting their immune system.

6. Breastfeeding Considerations: If you are breastfeeding, ensure that you are also taking care of your own breast hygiene. If you have any signs of a yeast infection on your nipples, it can be transmitted to the baby during feeding.


Conclusion
While recurrent oral thrush can be distressing for both the baby and the parents, understanding its causes and implementing preventive measures can significantly reduce the frequency of occurrences. It’s essential to maintain good oral hygiene, monitor feeding practices, and consult healthcare professionals for persistent cases. With proper management, most infants outgrow this condition as their immune systems mature and their oral flora balance improves.

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