Primary Salivary Gland Tumors: Diagnosis and Treatment Options - Oncology

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Primary salivary gland tumor


Hello Doctor, my mother's lymph nodes are swollen and painful.
She underwent ultrasound and fine needle aspiration biopsy at two different hospitals, and the two test reports are different.
The first report indicates a Warthin tumor, which is benign; the second report does not rule out the possibility of a malignant tumor, and the doctor has arranged for her to have surgery as soon as possible.
Should she undergo surgery? Which report is more reliable? Both tests were done within a week, but my mother's neck is getting larger day by day...

kommy, 20~29 year old female. Ask Date: 2005/03/11

Dr. Chen Sirong reply Oncology


Hello: Please proceed with the surgery as soon as possible to remove the entire tumor for pathological examination in order to confirm the diagnosis.
Sincerely, Dr.
Chen Sih-Jung, Oncology.

Reply Date: 2005/03/11

More Info


When it comes to primary salivary gland tumors, the diagnosis and treatment options can be quite complex, especially when faced with conflicting pathology reports, as in your mother's case. Salivary gland tumors can vary widely in their behavior, ranging from benign tumors like Warthin's tumor to malignant tumors that require more aggressive treatment.
Understanding Salivary Gland Tumors:
1. Types of Tumors: Salivary gland tumors can be classified into benign and malignant categories. Benign tumors, such as Warthin's tumor, are generally slow-growing and less likely to spread. Malignant tumors, on the other hand, can be aggressive and may metastasize to other parts of the body.

2. Diagnosis: The diagnosis of salivary gland tumors typically involves imaging studies (like ultrasound or MRI) and fine needle aspiration (FNA) biopsy. The FNA can provide cytological samples that help in determining the nature of the tumor. However, the accuracy of these tests can vary, and sometimes they may yield conflicting results, as seen in your mother's case.

3. Interpreting Conflicting Reports: In your situation, one report indicates a benign Warthin tumor, while the other suggests the possibility of a malignant tumor. This discrepancy can arise due to several factors, including the sampling technique, the experience of the pathologist, and the inherent variability in tumor presentation.
4. Symptoms and Clinical Presentation: The fact that your mother’s lymph nodes are enlarging and causing pain is concerning. Rapid growth of a lymph node, especially in the context of a potential malignancy, warrants further investigation. Pain and swelling can indicate inflammation or malignancy, and these symptoms should not be overlooked.

5. Surgical Considerations: Given the conflicting reports and the concerning symptoms, surgical intervention may be warranted. Surgery is often the definitive treatment for salivary gland tumors, especially if there is a suspicion of malignancy. The surgical approach allows for direct visualization and complete excision of the tumor, which can also provide a more definitive diagnosis through histopathological examination of the excised tissue.

6. Consultation with Specialists: It is crucial to discuss these findings with an otolaryngologist (ENT specialist) or a head and neck surgeon who specializes in salivary gland tumors. They can provide a comprehensive evaluation and recommend the best course of action based on the most recent imaging and pathology results.

7. Follow-Up and Monitoring: If surgery is performed, the excised tissue will be thoroughly examined to determine the exact nature of the tumor. If it is found to be malignant, further treatment options, such as radiation or chemotherapy, may be necessary.

In conclusion, while the benign nature of Warthin's tumor is reassuring, the rapid enlargement of the lymph nodes and the conflicting pathology reports suggest that surgical intervention may be the best option to ensure a definitive diagnosis and appropriate treatment. It is essential to have a thorough discussion with your healthcare provider to weigh the risks and benefits of surgery in your mother's specific case.

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