and Treating Genital Warts: A Comprehensive Guide - Obstetrics and Gynecology

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Genital warts


I am an ordinary office worker who has been suffering from condylomata acuminata for over four years.
During this time, I have had no sexual partners and only discovered my condition earlier this year.
The lesions are concentrated in the mid-section of the labia majora and the vaginal opening.
I have been using Aldara cream for over seven weeks.
In the second week, I experienced a severe infection near the vaginal opening, not directly on the warts but adjacent to the most severe lesions.
The wound has a white film covering it.
After using Betadine ointment, acyclovir (Zovirax), Cleocin (150mg capsule), and Albothyl solution, the wound has significantly improved and shrunk, but it has not healed completely after six weeks.
Currently, I am using Aldara (once daily) and Albothyl (5mg for sitz baths daily).
The following questions are ones I am too embarrassed to ask in front of other patients in the clinic.
Although I have tried to research online, there are still some uncertainties.
Your answers will be for my personal reference only.
Question 1: Why does ulceration occur? Is it related to herpes? (I am unsure if I am infected with the herpes virus.)
Question 2: If the warts have invaded the vagina or even the uterus, how should this be managed? What treatment options are available? What is the potential duration of treatment? Please also mention if health insurance covers these treatments.
(I hope to choose a treatment that requires no anesthesia or minimal anesthesia and does not leave scars.
I do not expect to be cured in one session; I am patient and willing to undergo multiple treatments, seeking a complete cure.)
Question 3: What sexually transmitted infection tests would you recommend for me?
Thank you very much for taking the time to answer these questions.

Zhenjing de bingren, 30~39 year old female. Ask Date: 2005/03/22

Dr. Huang Jianxun reply Obstetrics and Gynecology


You have received good medication treatment.
Please consult your physician to determine if further treatment is necessary for herpes, as it may indicate ulcerative disease.
A blood test for HSV IgG may be positive.
Warts are associated with human papillomavirus (HPV) infection, and HPV genotyping can be performed.

Reply Date: 2005/03/22

More Info


Genital warts, caused by the human papillomavirus (HPV), can be a challenging condition to manage, especially when complications arise, such as infections or ulcerations. Your experience with the treatment and the subsequent complications is not uncommon, and it's important to address your questions thoroughly.


Question 1: Why do ulcers occur? Are they related to herpes?
Ulcerations can occur for several reasons in the context of genital warts. The application of topical treatments like Aldara (imiquimod) can cause local irritation, leading to inflammation and, in some cases, ulceration. This is particularly true if the skin is sensitive or if the treatment is applied too frequently or in excessive amounts.
In your case, the severe infection that developed near the wart lesions could be due to a secondary bacterial infection, which is not uncommon when the skin barrier is compromised. The presence of a white film over the ulcerated area may indicate necrotic tissue or a buildup of exudate, which can occur in infected wounds.

Regarding herpes, it is possible to have co-infections. If you have not been tested for herpes simplex virus (HSV), it would be prudent to do so, as HSV can cause painful sores in the genital area and may complicate the healing of existing lesions. If you suspect you might have herpes, a healthcare provider can perform a swab test or blood test to confirm the diagnosis.


Question 2: If warts have invaded the vagina or cervix, how should they be managed? What treatment options are available?
If genital warts have spread to the vaginal or cervical areas, it is crucial to consult a healthcare provider for a thorough examination. Treatment options include:
1. Cryotherapy: Freezing the warts with liquid nitrogen. This method is effective and typically requires no anesthesia, though some discomfort may be experienced.

2. Electrosurgery: Using electrical currents to remove warts. This may require local anesthesia but is generally effective.

3. Laser therapy: This is used for larger or more extensive warts. It may require anesthesia and can be more costly.

4. Surgical excision: In cases where warts are extensive or resistant to other treatments, surgical removal may be necessary.

The duration of treatment can vary widely depending on the extent of the warts and the chosen method. Multiple sessions may be required, especially for extensive lesions. Regarding insurance coverage, many health insurance plans cover treatments for genital warts, but it is advisable to check with your provider for specifics.


Question 3: What STI screenings would you recommend?
Given your history and current symptoms, it would be wise to undergo a comprehensive sexual health screening, which should include:
1. HPV testing: To determine the type of HPV, especially if you have not been vaccinated.

2. Herpes Simplex Virus (HSV) testing: To rule out or confirm an HSV infection.

3. Chlamydia and Gonorrhea testing: These are common STIs that can be asymptomatic but may cause complications.

4. Syphilis testing: A blood test can determine if you have syphilis, which can also present with genital lesions.

5. HIV testing: It is essential to know your status, especially if you have multiple partners or are at risk.

In conclusion, managing genital warts and associated complications can be complex, but with the right medical guidance and treatment options, it is possible to achieve significant improvement. Always communicate openly with your healthcare provider about your symptoms and concerns, as they can tailor a treatment plan that best suits your needs.

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