Unexplained Pain in Diabetic Patients: A Case Study - Internal Medicine

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Inquiry about unknown ailments?


Hello, I would like to inquire about some unexplained pain.
Thank you.
Patient: Father, male, 68 years old, has been a diabetic for 15 years with blood sugar levels generally controlled around 130, but postprandial levels can rise to about 200.
Medical history: Recently admitted to the hospital due to weakness in both legs.
The doctor indicated that he had low potassium levels at 102.
After receiving saline treatment during hospitalization, his potassium level rose to 127, and he was discharged.
Recently, he has been experiencing pain in his legs from the hips to the knees for about a week, and he has difficulty walking.
Please provide some clarification.
Thank you.

Xiao Zhou, 30~39 year old female. Ask Date: 2005/05/05

Dr. Shi Guangzhong reply Internal Medicine


Your father should not have a potassium level of 102; after hospitalization and receiving saline, it has risen to 127.
It should be sodium that is low.
Hypokalemia can cause weakness in the legs, but hyponatremia can also lead to leg weakness, as well as low blood pressure, which can be life-threatening.
There are many causes of hyponatremia, and I won't elaborate on them here.
I recommend that you consult a specialist in metabolic disorders to avoid delaying treatment.

Reply Date: 2005/05/05

More Info


Understanding unexplained pain in diabetic patients can be quite complex, especially when considering the multifaceted nature of diabetes and its potential complications. In the case of your father, a 68-year-old male with a 15-year history of diabetes, there are several factors to consider regarding his recent symptoms of leg pain and weakness.

Firstly, diabetes can lead to various complications that may manifest as unexplained pain. One of the most common complications is diabetic neuropathy, which is a type of nerve damage that can cause pain, tingling, or numbness in the extremities. This condition is often a result of prolonged high blood sugar levels, which can damage the nerves over time. Although your father's blood sugar levels seem to be relatively controlled, fluctuations, especially postprandial (after meals), can still contribute to nerve damage.

Additionally, the recent hospitalization due to low potassium levels (hypokalemia) could also play a significant role in his current symptoms. Potassium is essential for muscle function, and low levels can lead to muscle weakness and cramping. The fact that his potassium levels were restored during his hospital stay is encouraging, but it is important to monitor his electrolyte levels regularly, as imbalances can recur, especially in diabetic patients who may have underlying kidney issues.

Moreover, the pain your father is experiencing from his hips to his knees could also be related to musculoskeletal issues. Diabetes is associated with an increased risk of osteoarthritis and other joint problems, which can lead to pain and discomfort, particularly in older adults. The combination of neuropathic pain and musculoskeletal pain can create a complex clinical picture that may be challenging to diagnose and treat.

In terms of management, it is crucial for your father to have regular follow-ups with his healthcare provider to monitor his diabetes, kidney function, and electrolyte levels. A thorough evaluation by a neurologist may also be beneficial to assess for diabetic neuropathy or other neurological conditions. Physical therapy could be recommended to help improve his mobility and strength, which may alleviate some of the pain he is experiencing.

Additionally, lifestyle modifications, including a balanced diet, regular exercise, and proper diabetes management, are essential. Ensuring that he maintains a healthy weight and engages in low-impact activities can help reduce stress on his joints and improve overall well-being.

In summary, unexplained pain in diabetic patients like your father can arise from a combination of factors, including diabetic neuropathy, electrolyte imbalances, and musculoskeletal issues. A comprehensive approach involving regular monitoring, appropriate medical evaluations, and lifestyle changes will be key to managing his symptoms effectively. It is advisable to maintain open communication with his healthcare team to address any concerns and adjust his treatment plan as necessary.

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