Persistent Hiccups After Cold Medication: Seeking Expert Advice - Gastroenterology and Hepatology

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After taking cold medicine, I have been experiencing hiccups for 3 to 4 hours non-stop?


Hello, doctor.
It has been 10 years...
I often seek medical attention after catching a cold.
After taking cold medicine, I start experiencing hiccups about 3 hours later.
The hiccups can last continuously for 3 to 4 hours, with intervals of about 30 seconds between each episode.
I would greatly appreciate any advice from experts.
(Please do not suggest that it is due to gas.) This issue seems to be beyond the scope of general practitioners.
I kindly ask for thorough consultation before providing a response! If there is even one doctor who can address this persistent hiccup symptom, it would be a blessing for many.
PS: If my words are offensive, please forgive me...
I am truly struggling with the pain caused by these hiccups and am on the verge of losing faith in Western medicine.

Yeren, 30~39 year old female. Ask Date: 2005/05/09

Dr. Chen Zhiping reply Gastroenterology and Hepatology


Hello, may I ask what ingredients are included in the cold medicine you are taking? If it is indeed the cold medicine that is causing your hiccups, that would be quite rare.
Generally, the causes of hiccups are mainly due to irritation of the stomach or diaphragm, such as overeating, consuming irritating foods, or pathological changes in the diaphragm that stimulate contractions.
I recommend you visit a gastroenterology clinic and bring your cold medication to have a doctor assess whether there is a connection between the hiccups and the medication.
The treatment for this typically involves prokinetic agents and muscle relaxants.
I understand this response may not fully satisfy you, and you are welcome to seek opinions from other physicians.
Sincerely, Dr.
Chen Zhi-Ping, Internal Medicine.

Reply Date: 2005/05/09

More Info


Persistent hiccups can be a frustrating and uncomfortable condition, especially when they occur frequently after taking cold medication. Hiccups, or singultus, are involuntary contractions of the diaphragm muscle, followed by a sudden closure of the vocal cords, which produces the characteristic "hic" sound. While hiccups are usually harmless and resolve on their own, persistent or chronic hiccups can be indicative of an underlying issue that may require medical attention.

In your case, it seems that you have been experiencing these persistent hiccups for about ten years, particularly after taking cold medication. This pattern suggests that there may be a specific trigger related to the medications you are taking or perhaps an underlying condition that has not yet been identified. It is important to consider the ingredients in the cold medications you are using, as some components can irritate the diaphragm or affect the nervous system, leading to hiccups.

Common causes of hiccups include:
1. Irritation of the diaphragm: This can occur due to overeating, consuming carbonated beverages, or swallowing air, but it can also be triggered by certain medications.

2. Gastroesophageal reflux disease (GERD): Acid reflux can irritate the diaphragm and lead to hiccups.

3. Nervous system disorders: Conditions affecting the brain or spinal cord can disrupt the signals that control the diaphragm.

4. Metabolic disorders: Imbalances in electrolytes or other metabolic issues can also contribute to hiccups.

5. Medications: Some medications, particularly those that affect the central nervous system, can lead to hiccups as a side effect.

Given that you have been experiencing this issue for a long time, it would be advisable to consult with a specialist, such as a gastroenterologist or a neurologist, who can conduct a thorough evaluation. They may recommend tests such as an endoscopy to check for GERD or other gastrointestinal issues, or imaging studies to assess the diaphragm and surrounding structures.

In the meantime, there are several home remedies and strategies that may help alleviate hiccups:
- Drinking water: Sipping cold water slowly or drinking a glass of water while holding your breath can sometimes help reset the diaphragm.

- Holding your breath: Take a deep breath and hold it for as long as you can, then exhale slowly.

- Swallowing a teaspoon of sugar: The graininess of sugar may help stimulate the vagus nerve, interrupting the hiccup reflex.

- Breathing into a paper bag: This can increase carbon dioxide levels in the blood, which may help stop the hiccup reflex.

- Gargling with water: This can stimulate the throat and potentially interrupt the hiccup cycle.

If your hiccups persist despite trying these remedies, or if they are accompanied by other concerning symptoms such as pain, difficulty swallowing, or significant weight loss, it is crucial to seek medical attention. Persistent hiccups can sometimes indicate a more serious underlying condition that requires treatment.

In conclusion, while hiccups are often benign, your long-standing experience with them, particularly following the use of cold medication, warrants further investigation. Consulting with a healthcare professional who can assess your specific situation and provide tailored advice is the best course of action.

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