Surgery vs. Medication: What’s Best for Your Gastroesophageal Reflux? - Gastroenterology and Hepatology

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Should I choose surgery or continue taking medication?


Hello, Doctor Chen.
I am from Hong Kong and I have been experiencing gastroesophageal reflux disease (GERD) for over a year.
Initially, I was taking Losec for my stomach issues.
I underwent two endoscopies at the hospital; during the first one, scarring was observed in my esophagus and stomach, and during the second endoscopy, polyps were found which were confirmed to be caused by inflammation.
I have now been on Nexium for 8 months and still need to take 20 mg of Nexium once daily.
However, if I stop the medication for a few days, the reflux symptoms return.
Besides considering fundoplication surgery, are there any better options available, or should I continue taking the medication?

Mr. Lai, 20~29 year old female. Ask Date: 2005/06/21

Dr. Chen Zhiping reply Gastroenterology and Hepatology


Hello, currently the treatment for GERD (Gastroesophageal Reflux Disease) primarily involves medication, such as the Nexium you are currently taking.
If symptoms are severe and recurrent, endoscopic treatment may be considered, such as suturing the junction between the stomach and esophagus, injecting substances to create a barrier, or using radiofrequency ablation to create scar tissue that increases resistance at the junction.
Alternatively, surgical intervention may be necessary.
Endoscopic treatments can be effective in the short term, but symptoms may recur after about a year as the junction may loosen again; surgical methods may provide more lasting results.
For your treatment, it is recommended to consult with a specialist at a medical center that offers endoscopic treatments for further evaluation.
Of course, long-term medication is the simplest approach.
If symptoms improve, you may reduce the dosage or take medication on demand as needed.
Sincerely, Dr.
Chen Zhi-Ping.
Note: I apologize for the previous incorrect response; it has now been corrected.
Thank you for your understanding.

Reply Date: 2005/06/21

More Info


When it comes to managing gastroesophageal reflux disease (GERD), the decision between continuing medication and opting for surgery can be complex and highly individualized. Based on your situation, it seems you have been dealing with GERD for over a year and have undergone two endoscopies, which revealed scarring in the esophagus and inflammation in the stomach. You have been on Nexium (esomeprazole), a proton pump inhibitor (PPI), for eight months, but you still experience reflux symptoms when you attempt to stop the medication.


Understanding GERD and Treatment Options
GERD is a chronic condition where stomach acid flows back into the esophagus, leading to symptoms like heartburn, regurgitation, and discomfort. The treatment options typically include lifestyle modifications, medications, and surgical interventions.

1. Medications: PPIs like Nexium are commonly prescribed for GERD as they effectively reduce stomach acid production. While they can provide relief, long-term use may lead to side effects, and some patients may experience a rebound effect, where symptoms worsen upon discontinuation. Other medications, such as H2 blockers (like famotidine or ranitidine), can also be used, but they generally have a milder effect compared to PPIs.

2. Lifestyle Modifications: Before considering surgery, it’s essential to evaluate lifestyle changes that can help manage GERD symptoms. This includes dietary adjustments (avoiding spicy foods, caffeine, and alcohol), weight management, and elevating the head during sleep. These changes can significantly impact symptom control and may reduce the need for medication.

3. Surgical Options: If medication fails to control symptoms or if you have complications from GERD (like esophageal strictures or Barrett's esophagus), surgical options may be considered. The most common surgical procedure for GERD is fundoplication, where the top of the stomach is wrapped around the lower esophagus to prevent reflux. This surgery can provide long-term relief for many patients, but it is not without risks and potential complications, such as difficulty swallowing or gas bloat syndrome.


Evaluating Your Options
Given your history of persistent symptoms despite medication, it may be worthwhile to explore further options:
- Consult a Specialist: It would be beneficial to consult with a gastroenterologist or a surgeon who specializes in GERD. They can evaluate your specific case, including the severity of your symptoms and any complications from your previous endoscopies, to determine if surgery is appropriate.

- Consider Endoscopic Treatments: There are also less invasive endoscopic procedures that can be considered, such as the Stretta procedure, which uses radiofrequency energy to strengthen the lower esophageal sphincter. These options may provide relief without the need for major surgery.

- Medication Adjustment: If you decide to continue with medication, discuss with your doctor the possibility of adjusting your regimen. Sometimes, a combination of medications or a different PPI may provide better control of symptoms.


Conclusion
In summary, the choice between continuing medication or pursuing surgery for GERD is not straightforward and should be made based on a thorough evaluation of your symptoms, response to treatment, and overall health. While medications can be effective, they may not be a permanent solution for everyone. Surgical options, particularly fundoplication, can offer long-term relief but come with their own set of risks. Engaging in a detailed discussion with your healthcare provider about your symptoms, treatment history, and lifestyle factors will help you make an informed decision that best suits your needs.

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