Treatment and Home Adjustment for Concurrent Hepatitis B and C Infection
Hello Doctor:
1.
If a patient is confirmed to have both Hepatitis B and Hepatitis C, it is said that the treatment approach for Hepatitis C (using interferon and antiviral medications) may be more effective and could also help suppress the severity of Hepatitis B.
Is this correct? What is the current success rate for patients in Taiwan who are receiving treatment for Hepatitis C and also have both Hepatitis B and C?
2.
It seems that the National Health Insurance Administration has allocated a budget to subsidize Hepatitis C treatment.
Why do some doctors say that patients need to pay out of pocket?
3.
How much does a six-month out-of-pocket treatment typically cost? Is the payment made at each visit, or is it required to be paid in full at once?
4.
Does the National Health Insurance cover the testing for hepatitis, and does it only check for the presence of liver inflammation without indicating the severity? Is this part of the testing out of pocket? If so, how much does it cost?
5.
Can a patient's clothing (such as underwear) be washed together with family members' clothes in the washing machine? Is there a risk of transmitting the virus to a partner through sexual activity? Should public chopsticks and serving spoons be used during meals?
6.
If a patient is following a diabetes diet, could this lead to nutritional deficiencies that may affect the liver?
Thank you for your responses to these many questions!
Tommy, 30~39 year old female. Ask Date: 2005/07/15
Dr. Lin Minghui reply Gastroenterology and Hepatology
Reply: Hello,
1.
Co-infection with hepatitis B and C is more complex to treat because there is an interaction between the two viruses; one may suppress the other.
Treating one virus may lead to the suppression or activation of the other.
The specific circumstances under which to treat and the treatment options are still unclear, and there is currently no consensus on treatment.
Recently, Kaohsiung Medical University used short-acting interferon combined with antiviral medications to treat 42 patients with both hepatitis B and C, achieving about a 60% rate of hepatitis C virus eradication, with approximately 12% of patients also achieving seroconversion for hepatitis B surface antigen.
The efficacy of long-acting interferon is still under investigation.
2.
The hepatitis B and C treatment pilot program requires meeting specific treatment criteria, including GPT levels and liver biopsy reports, for insurance coverage.
Treatment must be conducted under the supervision of physicians at hospitals participating in the hepatitis B and C pilot program.
3.
Treatment for hepatitis C involves the use of interferon and antiviral medications, with dosages related to body weight.
The choice between short-acting and long-acting interferon significantly affects cost; long-acting interferon combined with antiviral medications costs approximately NT$130,000.
If paying out-of-pocket, payment is required at the time of medication pickup.
4.
Hepatitis testing typically involves assessing the degree of liver inflammation through GPT and GOT levels.
For testing hepatitis C viral load and genotype, since our facility cannot perform these tests, they must be sent out for testing at an additional cost of approximately NT$2,500 to NT$3,000.
5.
Hepatitis C is transmitted through blood and bodily fluids, with sexual transmission being possible, particularly among individuals with multiple sexual partners.
It is not transmitted through sharing underwear or dining together.
6.
No, it will not be transmitted in those ways.
Sincerely, Dr.
Lin Ming-Hui, Internal Medicine
Reply Date: 2005/07/15
More Info
Managing co-infection with Hepatitis B (HBV) and Hepatitis C (HCV) presents unique challenges, as both viruses can affect liver function and overall health. Here’s a comprehensive overview addressing your questions and providing additional insights into treatment, care, and lifestyle considerations.
1. Treatment Approaches for Co-Infection: When dealing with both HBV and HCV, the treatment strategy often prioritizes HCV due to the availability of highly effective antiviral therapies. Direct-acting antivirals (DAAs) have revolutionized HCV treatment, achieving cure rates exceeding 95% in many cases. While interferon-based therapies were once common, they are less frequently used today due to their side effects and the availability of more effective treatments. In some cases, treating HCV can lead to a reduction in HBV activity, but this is not universally applicable. The success rate for patients in Taiwan with co-infection undergoing HCV treatment can vary, but studies suggest that around 60% may achieve a sustained virologic response (SVR), indicating effective treatment.
2. Insurance Coverage for Treatment: In Taiwan, the National Health Insurance (NHI) does provide coverage for HCV treatment under specific conditions, such as elevated liver enzymes or liver fibrosis. However, some physicians may recommend self-pay options if patients do not meet the criteria for insurance coverage or if they are seeking treatments not included in the NHI plan. It’s essential to discuss your specific situation with your healthcare provider to understand your options.
3. Cost of Self-Pay Treatment: The cost of HCV treatment can vary significantly based on the specific medications prescribed and the duration of treatment. For example, a course of treatment with DAAs can range from $13,000 to $80,000 New Taiwan Dollars (approximately $430 to $2,600 USD) for a typical 12-week regimen. Payment structures may vary; some clinics allow for installment payments, while others may require full payment upfront. It’s advisable to clarify this with your healthcare provider.
4. Liver Function Tests and Costs: The NHI typically covers basic liver function tests, which assess liver inflammation and damage. However, more specific tests, such as viral load testing for HCV or advanced liver fibrosis assessments, may not be fully covered and could incur out-of-pocket expenses. The cost for these additional tests can range from $2,500 to $3,000 New Taiwan Dollars (approximately $80 to $100 USD). Always check with your healthcare provider regarding what is covered under your insurance plan.
5. Infection Control and Hygiene: Hepatitis B and C are primarily transmitted through blood and bodily fluids. It is generally safe to wash clothes, including underwear, with those of family members. However, to minimize any risk of transmission, it is advisable to avoid sharing personal items that may come into contact with blood, such as razors or toothbrushes. Regarding sexual activity, while HCV can be transmitted sexually, the risk is lower compared to HBV. Using protection, such as condoms, is recommended to reduce the risk of transmission. Using separate utensils during meals is not necessary, but good hygiene practices should always be followed.
6. Diet and Nutritional Considerations: If you are managing diabetes alongside hepatitis, it is crucial to maintain a balanced diet that supports liver health without compromising blood sugar control. A diet rich in fruits, vegetables, whole grains, and lean proteins is beneficial. It’s essential to avoid excessive alcohol and high-fat foods, which can exacerbate liver issues. Consulting with a nutritionist who understands both diabetes and liver health can provide tailored dietary advice.
In summary, managing co-infection with HBV and HCV requires a comprehensive approach involving effective antiviral treatment, regular monitoring, and lifestyle adjustments. Engaging with healthcare providers to navigate treatment options, insurance coverage, and dietary needs is essential for optimal health outcomes.
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