Can Retrograde Neurotherapy Improve Amblyopia Beyond Golden Treatment Age? - Ophthalmology

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Retrograde neurotherapy can benefit amblyopic patients beyond the critical period for treatment?


My son is already 11 years old.
His treatment has been okay so far, but I saw an advertisement for the Taipei Light Point Clinic and went for a consultation.
The doctor said that one treatment course costs over 40,000 NT dollars, but there is a good chance of improvement.
I would like to know if there is any substantial efficacy and if there are any medical literature or outcome reports available?

Xiao Liao, 30~39 year old female. Ask Date: 2005/07/30

Dr. Liu Jingxian reply Ophthalmology


Hello, Xiao Liao: Based on your description, your child is around 11 years old, which is later than the ideal time for correction.
However, I still recommend that you have your child wear glasses with the correct prescription to correct the amblyopic eye.
Although the improvement in vision may not be as significant as that achieved by a normally functioning eye wearing glasses, it is still better than not wearing glasses at all.
As for "patching therapy" and "amblyopia training," they are not mandatory.
With certain stimulation, although the improvement in vision for the amblyopic eye may be limited, the appearance of the eye can look more normal and responsive.
Regarding the treatment of amblyopia solely through retrograde neurotherapy, there is still ongoing research to determine its efficacy without the combination of the aforementioned treatment methods, and I cannot confirm its effectiveness at this time.
Wishing you good health.
Dr.
Liu Jing-Hsi, Department of Ophthalmology, Taipei City Hospital, Zhongxing Branch, Taiwan e-Learning Academy.

Reply Date: 2005/07/30

More Info


Amblyopia, commonly referred to as "lazy eye," is a condition where one eye does not develop proper vision, leading to reduced visual acuity. Traditionally, the most effective treatment for amblyopia occurs during the critical period of visual development, typically before the age of 7. However, there has been growing interest in exploring treatment options for older children and even adults, particularly with the advent of new therapies such as retrograde neurotherapy.

Retrograde neurotherapy is a relatively novel approach that aims to stimulate the visual pathways and promote neural plasticity. The underlying principle is that the brain can still adapt and reorganize itself, even beyond the so-called "golden treatment age." This therapy often involves techniques that enhance visual processing and may include visual training exercises, perceptual tasks, and sometimes the use of specialized equipment.

While there is anecdotal evidence and some preliminary studies suggesting that retrograde neurotherapy may yield positive outcomes for individuals with amblyopia beyond the traditional treatment age, the scientific literature is still limited. Most studies on amblyopia have focused on younger populations, and the results for older children or adults are not as robust. A few studies have indicated that certain interventions, including perceptual learning and video game-based therapies, can improve visual acuity in older individuals, but these findings are not universally accepted and require further validation.

When considering the cost of treatment, such as the 40,000 NTD per course mentioned in your inquiry, it is essential to weigh the potential benefits against the financial investment. It is advisable to consult with a qualified ophthalmologist or optometrist who specializes in amblyopia treatment to discuss the specific details of retrograde neurotherapy, including its efficacy, safety, and any available clinical evidence.

In addition to retrograde neurotherapy, there are other treatment options that may be considered for amblyopia in older children, such as:
1. Occlusion Therapy: This involves patching the stronger eye to force the brain to use the weaker eye. While this is most effective in younger children, some older children may still benefit from this approach.

2. Atropine Drops: These drops can be used in the stronger eye to blur vision, encouraging the use of the amblyopic eye.

3. Vision Therapy: This includes a series of exercises designed to improve visual skills and processing. It can be tailored to the individual’s needs and may include activities that enhance depth perception, eye coordination, and focusing abilities.

4. Surgical Options: In some cases, surgery may be indicated, particularly if there are underlying issues such as strabismus (misalignment of the eyes).

In conclusion, while retrograde neurotherapy presents an intriguing option for treating amblyopia beyond the golden treatment age, more research is needed to establish its efficacy definitively. It is crucial to have an open discussion with your child's healthcare provider about the potential benefits and risks associated with this treatment, as well as to explore other available options. Ultimately, the goal is to find a personalized approach that best suits your child's needs and maximizes their visual potential.

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