Is a 2.48 Neural Tube Defect Value Considered High or Normal? - Obstetrics and Gynecology

Share to:

Could you please provide the content you would like me to translate?


A value of 2.48 for the neural tube defect screening is considered elevated.
It is important to consult with your healthcare provider for further evaluation and interpretation of your results in the context of your overall health and pregnancy.

niki, 20~29 year old female. Ask Date: 2005/09/28

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: The AFP value of 2.48 MOM is indeed elevated.
Please discuss with your obstetrician whether to perform amniocentesis or a high-level ultrasound to rule out the possibility of neural tube defects.
Hsinchu City Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2005/09/28

More Info


A Neural Tube Defect (NTD) value of 2.48 can be a cause for concern, as it typically indicates an elevated risk for neural tube defects in a developing fetus. In general, the normal range for maternal serum alpha-fetoprotein (MSAFP) levels, which are often used to screen for NTDs, is usually considered to be between 0.5 and 2.0 multiples of the median (MoM). Values above this range may suggest an increased risk for conditions such as spina bifida or anencephaly.

When interpreting a value of 2.48, it is important to consider the context in which this measurement was taken. Factors such as gestational age, the specific testing method used, and the patient's individual health history can all influence the interpretation of the result. A value of 2.48 is indeed above the typical threshold and may warrant further investigation.

If the value is indeed elevated, it is crucial to follow up with a healthcare provider for additional testing and evaluation. This may include a detailed ultrasound to assess the fetal anatomy and look for any signs of neural tube defects or other abnormalities. In some cases, genetic counseling may also be recommended to discuss the implications of the test results and any potential next steps.

It is also worth noting that while an elevated NTD value can indicate a higher risk, it does not guarantee that a neural tube defect will occur. Many factors contribute to the development of NTDs, including genetic predispositions and environmental influences. Therefore, a comprehensive approach that includes both medical evaluation and counseling is essential for understanding the implications of the test results.

In summary, a Neural Tube Defect value of 2.48 is considered elevated and may indicate an increased risk for neural tube defects. It is important to consult with a healthcare provider for further evaluation and to discuss potential next steps, including additional testing and monitoring. Early detection and intervention can be crucial in managing any potential risks associated with neural tube defects.

Similar Q&A

Understanding Fundus Examination: Concerns for High Myopia Patients

Hello, doctor. I have high myopia, with one eye at -6.75 and the other at -6.25. Today, during a fundus examination with a digital scan, I had some difficulty with my left eye. They kept asking me to look to the right, but I was already doing so, and the machine still couldn'...


Dr. Gao Pilin reply Ophthalmology
Hello Ms. Wang: 1. It may or may not happen. 2. It could be a possibility, or it might just be congenital. However, normal vision indicates that it has not yet reached the level of glaucoma. 3. Each physician has their own way of making judgments, and interpretations may vary.

[Read More] Understanding Fundus Examination: Concerns for High Myopia Patients


Understanding Glaucoma Concerns in High Myopia Patients: Key Insights

Hello Doctor, I have high myopia with a prescription of -6.25 and -6.75. I would like to ask about my OCT results. The doctor at the clinic mentioned that my retinal nerve fiber layer is thinner, and my intraocular pressure was 20 and 21 on that day. Later, I went to the hospital...


Dr. Gao Pilin reply Ophthalmology
Hello Ms. Lin: 1. You might need to ask the interpreting physician; I'm not sure. 2. It could be normal. 3. It's possible.

[Read More] Understanding Glaucoma Concerns in High Myopia Patients: Key Insights


Understanding Discrepancies Between Eye Pressure and Visual Field Tests

Hello Doctor: My intraocular pressure has been consistently high, around 23 to 25 mmHg. There have been a few instances where it spiked to 31 mmHg, but the doctor said my optic nerve appears normal. However, the visual field test showed some defects. I am currently using medicati...


Dr. Cai Wenyuan reply Ophthalmology
Hello, visual field testing is a subjective examination that may have inherent errors. It often requires multiple comparisons over time to determine if there are any defects. Wishing you safety and health. Sincerely, Dr. Tsai Wen-Yuan, Director of the Ophthalmology Department, Ta...

[Read More] Understanding Discrepancies Between Eye Pressure and Visual Field Tests


Understanding 55% Optic Nerve Cupping in a Child: Key Concerns and Next Steps

Hello, doctor. Two days ago, I took my six-year-old daughter to an ophthalmology clinic for a vision check. Her vision is normal, but it was unexpectedly found that she has a 55% optic nerve cupping. Her intraocular pressure is normal, and her visual field test is normal. The doc...


Dr. Wang Yuwei reply Ophthalmology
Your daughter may indeed have a naturally larger optic nerve head depression, so it is important to monitor her intraocular pressure and visual fields. If there are any abnormalities in the future regarding intraocular pressure or visual fields, it could indicate glaucoma, which ...

[Read More] Understanding 55% Optic Nerve Cupping in a Child: Key Concerns and Next Steps


Related FAQ

Neural Tube Defects

(Obstetrics and Gynecology)

High-Risk Pregnancy

(Obstetrics and Gynecology)

Hyperprolactinemia

(Obstetrics and Gynecology)

Abnormal Bleeding

(Obstetrics and Gynecology)

Spontaneous Miscarriage

(Obstetrics and Gynecology)

Hormonal Imbalance

(Obstetrics and Gynecology)

Endometrial Hyperplasia

(Obstetrics and Gynecology)

Ca-125

(Obstetrics and Gynecology)

Fetal Growth Rate

(Obstetrics and Gynecology)

Down Syndrome

(Obstetrics and Gynecology)