What causes elevated prolactin levels?
Hello, Doctor.
My menstrual cycle has been regular, approximately every 32 days.
However, last month it was suddenly delayed by 10 days.
After an examination, the doctor said my prolactin level was high (52).
Why is this happening? I was also prescribed medication; can I choose not to take it? The side effects seem quite numerous.
Will this lead to infertility in the future? If my period comes on time this month, can I ignore the high prolactin levels from now on?
Ya Ya, 20~29 year old female. Ask Date: 2005/10/11
Dr. Zhong Wenzhen reply Obstetrics and Gynecology
Prolactin is produced by the pituitary gland; therefore, a pituitary adenoma can lead to hyperprolactinemia.
Additionally, it is classified as a stress hormone, and changes in lifestyle and stress levels can also cause hyperprolactinemia.
This condition can result in galactorrhea, amenorrhea (absence of menstruation), and is a potential cause of infertility.
If menstruation occurs regularly, prolactin levels may naturally return to normal, and a follow-up test can be conducted to confirm whether normalization has occurred.
Reply Date: 2005/10/11
More Info
Elevated prolactin levels, or hyperprolactinemia, can be a significant concern for women, particularly when it comes to menstrual irregularities and fertility. Prolactin is a hormone produced by the pituitary gland, and its primary role is to promote breast milk production after childbirth. However, elevated levels can occur for various reasons, and understanding these causes is crucial for managing your health.
Causes of Elevated Prolactin Levels:
1. Physiological Causes: Prolactin levels can naturally rise during pregnancy, breastfeeding, and even during sleep. Stress, both physical and emotional, can also lead to temporary spikes in prolactin levels.
2. Pathological Causes: Conditions such as prolactinomas (benign tumors of the pituitary gland), hypothyroidism, and other pituitary disorders can lead to chronic elevation of prolactin. Certain medications, particularly antipsychotics and antidepressants, can also increase prolactin levels.
3. Other Factors: Chest wall irritation, such as from surgery or trauma, and systemic diseases like liver or kidney disease can also contribute to elevated prolactin.
In your case, the sudden delay in your menstrual cycle and the finding of elevated prolactin levels (52 ng/mL) suggest that there may be an underlying issue that needs to be addressed. It is essential to follow up with your healthcare provider to determine the exact cause of your elevated prolactin and to discuss the implications for your menstrual health and fertility.
Concerns Regarding Treatment:
You mentioned being prescribed medication to manage your prolactin levels. While it is understandable to be concerned about potential side effects, it is crucial to weigh these against the risks of untreated hyperprolactinemia. Elevated prolactin can lead to menstrual irregularities, anovulation (lack of ovulation), and infertility. If left untreated, it may also cause galactorrhea (unexpected milk production) and bone density issues due to prolonged low estrogen levels.
The medications typically prescribed for elevated prolactin, such as cabergoline or bromocriptine, are generally effective and well-tolerated. They work by reducing prolactin production and can help restore normal menstrual cycles and fertility. While side effects can occur, they are often manageable, and many women find that the benefits of treatment outweigh the risks.
Monitoring and Future Considerations:
If your menstrual cycle returns to normal this month, it is tempting to disregard the elevated prolactin levels. However, it is essential to continue monitoring your hormone levels and menstrual health. Regular follow-ups with your healthcare provider can help ensure that any underlying issues are addressed and that your reproductive health is maintained.
In summary, elevated prolactin levels can have various causes and implications for women's health. It is vital to work closely with your healthcare provider to understand the underlying reasons for your elevated prolactin, the necessity of treatment, and the potential impact on your menstrual cycle and fertility. Ignoring elevated prolactin levels could lead to more significant issues down the line, so proactive management is key.
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