Submandibular Swelling: Is It a Sign of Nasopharyngeal Cancer? - Otolaryngology

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Submandibular swelling


Hello, Dr.
Hsu.
Last week, I felt a lump about one centimeter in size under my left ear.
It hurts when pressed, and the surface feels somewhat smooth.
There are no visible signs of a lump from the outside.
I went to Chang Gung Memorial Hospital for a consultation, where the doctor used an endoscope to examine my nose and nasopharynx, stating that nothing suspicious was found.
Blood tests were also conducted.
After the consultation, the lump has not increased in size, but it hasn't decreased either (the doctor did not prescribe any anti-inflammatory medication), and I have started to occasionally feel headaches on the left side of my head.
I have a history of allergic rhinitis and sinusitis.
I would like to know if the likelihood of having nasopharyngeal cancer is high in this situation.
Thank you for your response.

Xiao Lan Zi, 20~29 year old female. Ask Date: 2005/10/19

Dr. Xu Jiazhen reply Otolaryngology


Hello: In response to your question, there is indeed a lymphatic drainage area located beneath the ear that comes from the nasopharynx.
However, it is difficult to determine the exact location of what you refer to as "beneath the ear" and the depth of the lump based on the information provided.
Blood tests can measure EBV levels, and a nasopharyngoscopy can be performed.
Conservative treatment with antibiotics and anti-inflammatory medications for 2-4 weeks is recommended.
If there is no reduction in size or if the lump increases, consideration can be given to excising a pathological sample.
The association between allergic rhinitis, sinusitis, and nasopharyngeal carcinoma is not high.

Reply Date: 2005/10/19

More Info


When it comes to submandibular swelling, particularly in the context of your concerns about nasopharyngeal cancer, it is essential to consider several factors before jumping to conclusions. The presence of a lump in the submandibular area can be attributed to various causes, including benign conditions, infections, or malignancies.

Firstly, the characteristics of the lump you described—about one centimeter in size, tender upon pressure, and smooth in texture—are important. Tenderness often suggests an inflammatory process, which could indicate an infection or reactive lymphadenopathy rather than a malignant process. In your case, the fact that the lump has not increased in size and that an endoscopic examination did not reveal any suspicious lesions in the nasopharynx is reassuring.
The absence of visible abnormalities during the endoscopic examination is a positive sign, as nasopharyngeal cancer typically presents with more pronounced symptoms or findings. Additionally, your history of allergic rhinitis and sinusitis could contribute to localized swelling or discomfort in the submandibular region, as these conditions can lead to lymph node enlargement due to inflammation.

Regarding the possibility of nasopharyngeal cancer, it is important to note that this type of cancer is often associated with specific risk factors, including Epstein-Barr virus (EBV) infection, a diet high in salt-cured foods, and a family history of the disease. If you do not have these risk factors, the likelihood of having nasopharyngeal cancer decreases.

Your symptoms of occasional headaches could be related to sinus pressure or other benign causes, especially given your history of sinusitis. However, if these headaches become more frequent or severe, or if you develop additional symptoms such as nasal obstruction, epistaxis (nosebleeds), or changes in hearing, it would be prudent to follow up with your healthcare provider for further evaluation.

In terms of management, since your doctor did not prescribe antibiotics, it suggests that they did not find evidence of a bacterial infection that would require treatment. However, if the lump persists or worsens, or if you develop new symptoms, it would be advisable to seek further evaluation. This could include imaging studies such as an ultrasound or CT scan to assess the lymph nodes and surrounding structures more thoroughly.

In summary, while the presence of a submandibular lump can be concerning, the current findings and your medical history suggest that the likelihood of nasopharyngeal cancer is low. Continuous monitoring of the lump and any new symptoms is essential. If you have ongoing concerns, do not hesitate to consult with your healthcare provider for further assessment and peace of mind. Regular follow-ups and open communication with your doctor will help ensure that any changes in your condition are promptly addressed.

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