Is It Safe to Prescribe Omeprazole Without Proper Diagnosis? - Internal Medicine

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The doctor prescribed Lansoprazole to my mother without performing an X-ray or endoscopy?


Hello, Doctor: My mother (46 years old) recently experienced gastrointestinal discomfort and was referred to a clinic in Keelung City by a friend.
The physician (approximately 60 years old) performed a physical examination after my mother reported her symptoms and declared that she might have a gastric ulcer.
He prescribed "Losec" (20 mg Omeprazole) for her.
After taking the medication for ten consecutive days, she returned for a follow-up appointment, where the doctor informed her that her discomfort had improved and that she did not need to continue the medication.
I would like to ask the following questions: (1) Can the physician diagnose a gastric ulcer based solely on a physical examination without X-ray or endoscopy? (2) If it is indeed a gastric ulcer, will stopping the medication after ten days lead to any complications? (3) If it is not a gastric ulcer, should my mother stop the medication immediately? How should she proceed? (4) During the follow-up visit, the doctor mentioned that this medication is an antibiotic; can it lead to antibiotic resistance? In summary, I would like to know if this diagnosis is somewhat inappropriate and how my mother should handle the situation.
Thank you.

A-Wen, 20~29 year old female. Ask Date: 2005/11/20

Dr. Xiao Yongxun reply Internal Medicine


Hello: In response to your questions.
1.
It is advisable to discuss the issues you raised with the physician.
2.
The diagnosis of gastric ulcers can be based on clinical symptoms and medical history, upper gastrointestinal barium studies, and upper gastrointestinal endoscopy; the definitive diagnosis is generally made primarily through upper gastrointestinal endoscopy.
However, in the absence of equipment, inferences can still be made.
3.
For gastric ulcers associated with Helicobacter pylori infection, antibiotic treatment is generally recommended for about 1-2 weeks.
Of course, inappropriate use of antibiotics may lead to the development of resistance.
4.
Losec (Omeprazole) is a proton pump inhibitor that is very effective for gastric ulcers; however, it is usually taken for a period of time (ranging from several days to several weeks) before discontinuation.
Current studies indicate that significant side effects are rare.
Additionally, it is not an antibiotic.
5.
For your mother's concerns, it is still recommended to discuss them with the physician or your family doctor.

Reply Date: 2005/11/20

More Info


When it comes to prescribing medications like omeprazole, especially without a thorough diagnostic process, there are several important considerations to keep in mind. Omeprazole is a proton pump inhibitor (PPI) commonly used to treat conditions related to excessive stomach acid, such as gastroesophageal reflux disease (GERD) and peptic ulcers. However, its prescription should ideally be based on a comprehensive evaluation of the patient's symptoms and medical history.

1. Diagnosis Without Proper Testing: It is concerning that the physician diagnosed a potential gastric ulcer based solely on palpation without conducting further diagnostic tests such as an endoscopy or imaging studies. While a physical examination can provide some insights, it is not definitive for diagnosing conditions like gastric ulcers. Endoscopy is the gold standard for diagnosing ulcers, as it allows direct visualization of the gastric mucosa and can also facilitate biopsy if necessary. Therefore, a diagnosis made without proper investigation may lead to mismanagement of the patient's condition.

2. Discontinuing Omeprazole After Ten Days: If your mother was indeed suffering from a gastric ulcer, abruptly stopping omeprazole after ten days may not be advisable. PPIs like omeprazole are typically prescribed for a longer duration to allow for adequate healing of the ulcer. Stopping the medication prematurely could potentially lead to a recurrence of symptoms or complications. It is crucial to follow up with a healthcare provider for further evaluation and to determine the appropriate duration of therapy.

3. If Not a Gastric Ulcer: If your mother does not have a gastric ulcer, it is essential to assess the underlying cause of her gastrointestinal discomfort. Discontinuing omeprazole without understanding the root cause may lead to a resurgence of symptoms. A healthcare provider should evaluate her symptoms further, possibly considering other diagnostic tests or referrals to a gastroenterologist for a more comprehensive assessment.

4. Misunderstanding of Omeprazole as an Antibiotic: It is important to clarify that omeprazole is not an antibiotic; it is a medication that reduces stomach acid production. The misconception that it is an antibiotic may lead to confusion regarding the potential for antibiotic resistance. Since omeprazole does not possess antibiotic properties, concerns about developing resistance do not apply. However, long-term use of PPIs can lead to other issues, such as nutrient malabsorption (e.g., magnesium, calcium, vitamin B12) and an increased risk of gastrointestinal infections.

In summary, the prescribing of omeprazole without a thorough diagnostic workup raises concerns about the appropriateness of the treatment. It is advisable for your mother to seek a second opinion from a gastroenterologist or her primary care physician, who can conduct the necessary tests to confirm or rule out a gastric ulcer or other gastrointestinal conditions. Additionally, if she continues to experience symptoms, it is essential to address them with a healthcare professional rather than relying solely on over-the-counter medications or previous prescriptions. Proper management of gastrointestinal issues often requires a tailored approach based on accurate diagnosis and ongoing monitoring.

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