Managing Leprosy: Treatment Duration, Fish Oil Myths, and Foot Care - Hansens Disease

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Cod liver oil


Hello Dr.
Lee: Regarding the two-year treatment for leprosy, will a blood test report determine whether to stop the medication after two years? Additionally, there are claims among patients that taking cod liver oil can prevent skin darkening; is this correct? Are there other methods? I have taken it, but my skin is still dark.
Also, how can we improve the atrophy of the soles of the feet caused by leprosy? Thank you for your response!

Pengyou, 30~39 year old female. Ask Date: 2005/11/22

Dr. Li Zhongxian reply Hansens Disease


Hello! 1.
After two years of treatment for leprosy, a slit skin smear examination is conducted to check for the presence of Mycobacterium leprae, which determines whether to discontinue medication and observe the patient.
This is based on the recommendations of the World Health Organization (WHO), not the "blood test" you mentioned.
2.
Cod liver oil contains fat-soluble vitamins A and D, which are beneficial for the body's metabolism, but please do not exceed the recommended dosage.
The multidrug therapy (MDT) for leprosy includes Lamprene (B663), a capsule formulation that may cause skin pigmentation changes to a dark brown color with long-term use.
After discontinuation of the medication, it will take some time for the body to metabolize and eliminate it, so there is no need for concern.
3.
Leprosy and leprosy reactions can lead to limb deformities and skin lesions.
Patients with foot atrophy should consult a rehabilitation specialist to assess and customize appropriate protective footwear to avoid prolonged improper pressure on the soles of the feet, which can lead to skin abrasion and recurrent ulcers.

Reply Date: 2005/11/22

More Info


Managing leprosy, also known as Hansen's disease, involves a comprehensive approach that includes understanding the treatment duration, addressing common myths about supplements like fish oil, and providing care for foot-related complications that may arise from the disease.


Treatment Duration
Leprosy is primarily treated with a multi-drug therapy (MDT) that typically lasts for a minimum of two years, depending on the severity and type of the disease. The World Health Organization (WHO) recommends that treatment duration is determined not by blood tests but rather by clinical evaluations and skin smears. After two years of treatment, a skin smear test is performed to check for the presence of Mycobacterium leprae, the bacteria that causes leprosy. If the smear is negative, it is generally safe to discontinue treatment. However, continuous monitoring is essential, as some patients may require extended therapy based on their clinical response.


Fish Oil Myths
There is a common belief among some patients that consuming fish oil can prevent skin darkening associated with leprosy treatment. Fish oil is rich in omega-3 fatty acids and vitamins A and D, which can support overall health and skin condition. However, it is important to note that the skin darkening experienced during leprosy treatment is often due to the medication itself, particularly from drugs like Lamprene (clofazimine), which can cause pigmentation changes. While fish oil may have some benefits for skin health, it is unlikely to reverse or prevent the pigmentation changes caused by the medication. If patients are concerned about skin discoloration, they should discuss this with their healthcare provider for appropriate management strategies.


Foot Care and Management of Atrophy
Foot care is crucial for patients with leprosy, especially those who experience foot atrophy or deformities due to nerve damage. Patients should be proactive in managing their foot health to prevent complications such as ulcers or infections. Here are some recommendations:
1. Regular Foot Inspections: Patients should inspect their feet daily for any cuts, blisters, or signs of infection. Since leprosy can cause loss of sensation, injuries may go unnoticed.

2. Proper Footwear: Custom-made shoes or orthotics may be necessary to provide adequate support and prevent pressure sores. Consulting with a rehabilitation specialist can help in obtaining the right footwear.

3. Moisturizing: Keeping the feet moisturized can prevent cracking and dryness, which can lead to infections.

4. Physical Therapy: Engaging in physical therapy can help maintain mobility and strength in the feet and legs, which is especially important for those experiencing muscle atrophy.

5. Regular Follow-ups: Regular visits to healthcare providers for monitoring and management of leprosy-related complications are essential. This includes assessments by dermatologists and rehabilitation specialists.

In conclusion, managing leprosy requires a multifaceted approach that includes adherence to treatment protocols, dispelling myths about supplements, and ensuring proper foot care to prevent complications. Patients should maintain open communication with their healthcare providers to address any concerns and receive personalized care tailored to their needs.

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