Persistent Stomach Discomfort and Nausea: When to Seek Further Evaluation? - Gastroenterology and Hepatology

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Abdominal discomfort... slight swelling in the upper right quadrant... frequent nausea and urge to vomit?


Hello, doctor.
I've been experiencing discomfort in my stomach for a long time.
I had an endoscopy a year and a half ago, which showed some minor lesions in my stomach.
I also had an abdominal ultrasound, which indicated no major issues.
I usually only take medication occasionally when I feel uncomfortable, but the discomfort always occurs in the same area (upper right side).
Recently, I've been feeling some swelling in the upper right part of my stomach, and I have a constant urge to vomit.
I need to elevate my pillow while sleeping.
This is the first time I've encountered this situation, and it's quite distressing.
I'm still taking medication, but it seems like there hasn't been any significant improvement.
Should I undergo another endoscopy, or should I continue taking medication and observe for a while? Thank you.

A-Jia, 20~29 year old female. Ask Date: 2006/02/24

Dr. Lin Minghui reply Gastroenterology and Hepatology


Hello: Abdominal pain, nausea, and a desire to vomit, especially with nighttime pain, may indicate duodenal or gastrointestinal disorders, including gastroesophageal reflux disease (GERD), inflammation, ulcers, or even malignancies.
If symptoms persist, it is advisable to seek medical attention, and if necessary, arrange for an endoscopy to confirm the diagnosis.
Sincerely, Dr.
Lin Ming-Hui, Internal Medicine.

Reply Date: 2006/02/24

More Info


Persistent stomach discomfort and nausea can be quite distressing, especially when you've already undergone previous evaluations like an endoscopy and abdominal ultrasound. Given your history of gastric issues, including the presence of a superficial ulcer noted during your last endoscopy, it's important to approach your current symptoms with caution.

Your description of discomfort localized to the upper right side of your abdomen, along with a feeling of swelling and persistent nausea, raises several considerations. The fact that you have to elevate your head while sleeping suggests that there may be an underlying issue related to gastroesophageal reflux or possibly a more significant gastric condition.
First and foremost, it is essential to recognize that while medications can provide symptomatic relief, they do not address the underlying causes of gastric discomfort. If your symptoms have persisted or worsened despite medication, it may be time to seek further evaluation. Here are some key points to consider:
1. Re-evaluation of Symptoms: Since your symptoms have changed and you are experiencing new sensations such as swelling and persistent nausea, a re-evaluation is warranted. Symptoms that are new or have changed in character should always be taken seriously, especially in the context of a history of gastric issues.

2. Endoscopy Consideration: Given your previous history of gastric ulcers and the current symptoms, repeating an endoscopy could be beneficial. This procedure allows for direct visualization of the gastric mucosa and can help identify any new lesions, ulcers, or other abnormalities that may have developed since your last examination. It can also provide an opportunity for biopsy if necessary.

3. Potential for Complications: The symptoms you describe could indicate complications such as gastritis, peptic ulcers, or even more serious conditions like gastric cancer, especially considering your ongoing discomfort and the need for positional adjustments while sleeping. It is crucial to rule out these possibilities.

4. Medication Review: While you are currently on medication, it may be helpful to review the specific medications you are taking. Proton pump inhibitors (PPIs) like Nexium are commonly prescribed for gastric issues, but they can have side effects and may not be suitable for everyone. Discussing your medication regimen with your healthcare provider can help ensure that you are receiving the most appropriate treatment.

5. Lifestyle and Dietary Modifications: In addition to medical treatment, lifestyle and dietary changes can significantly impact gastric health. Avoiding trigger foods, eating smaller meals, and not lying down immediately after eating can help alleviate symptoms. Keeping a food diary may also help identify any specific foods that exacerbate your discomfort.

6. Follow-Up with Healthcare Provider: It is crucial to maintain open communication with your healthcare provider. If your symptoms persist or worsen, do not hesitate to reach out for further evaluation. Your provider may recommend additional tests, such as imaging studies or laboratory tests, to assess your condition more thoroughly.

In summary, given your ongoing symptoms and the changes you've experienced, it would be prudent to seek further evaluation, potentially including another endoscopy. Your health and comfort are paramount, and addressing these symptoms proactively can help prevent further complications. Always consult with your healthcare provider to determine the best course of action tailored to your specific situation.

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