Can I Donate Bone Marrow or Organs with Hepatitis B Carrier Status? - Gastroenterology and Hepatology

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Bone marrow donation or liver and kidney donation or..?


I was diagnosed as a carrier of hepatitis B six years ago after giving birth.
I only know that it is a one plus one minus situation, and that newborns are not required to receive immunoglobulin.
My questions are: 1.
Can I donate bone marrow, liver, or kidney? 2.
Can I receive an organ transplant? Thank you for taking the time to answer my questions.
Wishing you all the best.

Kai Ma, 30~39 year old female. Ask Date: 2001/10/12

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, if you are confirmed to be a carrier, it is generally not advisable to donate bone marrow or organs such as the liver or kidneys (as it may transmit the infection to the recipient), although there may be exceptions.
You should monitor the changes in your hepatitis B status annually, as you may still receive organ transplants, but new organs can also become infected.
Wishing you safety and health!

Reply Date: 2001/10/12

More Info


As a Hepatitis B carrier, your ability to donate organs or bone marrow is a nuanced topic that involves understanding both medical guidelines and the implications of your condition.
1. Can I Donate Bone Marrow or Organs?
According to current medical guidelines, individuals who are carriers of Hepatitis B can donate certain tissues, such as bone marrow, skin, and corneas. However, organ donation, particularly of solid organs like the liver or kidneys, is more complex. The primary concern is the potential transmission of the Hepatitis B virus (HBV) to the recipient.
In the case of kidney donation, while some centers may allow Hepatitis B carriers to donate under specific circumstances, it is generally discouraged due to the risk of transmitting the virus. The same applies to liver donation; the risk of transmitting HBV to the recipient is a significant concern, and most transplant centers will not accept organs from Hepatitis B carriers.
It is also important to note that the guidelines may vary by region and specific transplant centers. Some may have protocols in place for Hepatitis B carriers, especially if the recipient is also a carrier or has been vaccinated against Hepatitis B. Therefore, it is crucial to consult with a transplant specialist or a medical professional at a transplant center to get personalized advice based on your health status and the policies of the institution.

2. Can I Receive a Transplant?
As a Hepatitis B carrier, you can receive a transplant, but there are considerations to keep in mind. If you require a liver transplant, for instance, the medical team will evaluate your overall liver function, the extent of liver damage, and the presence of any complications related to Hepatitis B.
Hepatitis B can lead to chronic liver disease, which may necessitate a liver transplant if the liver is severely damaged. However, the presence of Hepatitis B can complicate the post-transplant management. Patients who receive a liver transplant from a Hepatitis B carrier may require antiviral therapy to prevent reactivation of the virus after the transplant.
Additionally, if you are considering receiving a kidney transplant, your Hepatitis B status will be evaluated in conjunction with other factors, such as your overall health, kidney function, and any other underlying conditions. The transplant team will work to ensure that the benefits of the transplant outweigh the risks associated with your Hepatitis B status.

In conclusion, while you may have the option to donate certain tissues, organ donation as a Hepatitis B carrier is generally not permitted due to the risks involved. On the other hand, receiving a transplant is possible, but it requires careful evaluation and management to ensure the best outcomes for both you and the potential donor organ. Always consult with your healthcare provider or a transplant specialist for the most accurate and personalized information regarding your situation.

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