Kidney Function and Health Risks: A Patient's Guide - Internal Medicine

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Kidney Disease Consultation


I previously underwent a health check at a laboratory, and my test results showed cholesterol: 230 mg/dL, creatinine: 1.7 mg/dL, uric acid: 8.5 mg/dL, potassium: 2.9 mmol/L, and urine protein: ++.
I would like to ask the doctor how much kidney function I have left, or if my hypertension is causing kidney damage.
My usual blood pressure is around 130-140 mmHg systolic and 90 mmHg diastolic.
Additionally, I often experience frequent urination and anemia, and I have lost 5-6 kilograms in weight over the past two months.
What could be the cause of this?

Ms. Zhang, 50~59 year old female. Ask Date: 2006/04/07

Dr. Yang Jun reply Internal Medicine


Hello: In response to your question, the tests listed in your inquiry can diagnose chronic kidney disease, hyperlipidemia, hyperuricemia, hypokalemia, and hypertension.
Kidney disease is related to hypertension, and additionally, diet, medications, systemic diseases, and autoimmune disorders can also lead to impaired kidney function.
It is essential to connect with a nephrologist as soon as possible for further evaluation and treatment.
The calculation of remaining kidney function can be determined through a 24-hour urine test, along with individual weight, age, and biochemical tests.
These assessments can be performed in a nephrology outpatient clinic.

Reply Date: 2006/04/07

More Info


Understanding kidney function and the associated health risks is crucial, especially when faced with abnormal lab results. Based on the information you've provided, let's break down your situation and address your concerns.


Kidney Function and Lab Results
Your lab results indicate several important factors:
1. Creatinine (1.7 mg/dL): This level is elevated, as normal ranges typically fall between 0.7 and 1.4 mg/dL. Elevated creatinine levels suggest that your kidneys are not filtering waste effectively, which could indicate impaired kidney function.

2. Uric Acid (8.5 mg/dL): This level is also elevated. High uric acid can lead to conditions like gout and may contribute to kidney stone formation, which can further impair kidney function.

3. Potassium (2.9 mmol/L): This level is low (normal range is typically 3.5 to 5.0 mmol/L). Low potassium can lead to various health issues, including muscle weakness and heart problems.

4. Protein in Urine (++): The presence of protein in urine (proteinuria) is a sign of kidney damage. Healthy kidneys typically do not allow significant amounts of protein to pass into the urine.

5. Cholesterol (230 mg/dL): This level is above the recommended limit, which can contribute to cardiovascular diseases, further complicating kidney health.


Blood Pressure and Kidney Health
Your blood pressure readings (systolic 130-140 mmHg and diastolic around 90 mmHg) indicate that you may have hypertension. High blood pressure is a significant risk factor for kidney disease, as it can damage the blood vessels in the kidneys over time, leading to decreased kidney function. It is essential to manage your blood pressure effectively to prevent further kidney damage.


Symptoms and Weight Loss
The symptoms you mentioned—frequent urination, anemia, and recent weight loss—are concerning. Frequent urination can be a sign of kidney issues, diabetes, or urinary tract infections. Anemia in kidney disease is often due to the kidneys' reduced ability to produce erythropoietin, a hormone that stimulates red blood cell production. Weight loss could be attributed to several factors, including dietary changes, loss of appetite, or underlying health issues such as chronic kidney disease or other metabolic disorders.


Recommendations
1. Consult a Nephrologist: Given your elevated creatinine and uric acid levels, along with proteinuria, it is crucial to consult a nephrologist (kidney specialist). They can provide a comprehensive evaluation of your kidney function and recommend appropriate treatment options.

2. Monitor Blood Pressure: Regular monitoring and management of your blood pressure are essential. Lifestyle changes, such as reducing sodium intake, maintaining a healthy weight, and regular physical activity, can help manage hypertension.

3. Dietary Adjustments: Consider a diet low in protein, sodium, and potassium, depending on your nephrologist's recommendations. A dietitian specializing in kidney health can help you create a meal plan that meets your nutritional needs while protecting your kidney function.

4. Hydration: Ensure you are adequately hydrated, but follow your doctor's advice regarding fluid intake, especially if you have any restrictions due to kidney function.

5. Regular Monitoring: Regular follow-ups with your healthcare provider to monitor kidney function, blood pressure, and other relevant health markers are crucial. This will help in early detection of any further decline in kidney function.

6. Address Anemia: If anemia is confirmed, your doctor may recommend treatments such as iron supplements or erythropoiesis-stimulating agents.


Conclusion
Your current lab results and symptoms suggest that your kidney function may be compromised, likely exacerbated by hypertension and possibly other underlying conditions. It is vital to take proactive steps by consulting with healthcare professionals, making necessary lifestyle changes, and adhering to any prescribed treatments. Early intervention can significantly impact the progression of kidney disease and overall health.

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