Elevated Hepatitis B Surface Antigen Levels: What You Need to Know - Gastroenterology and Hepatology

More Info

---

Elevated levels of Hepatitis B surface antigen (HBsAg) can indicate an active Hepatitis B virus (HBV) infection. As a Hepatitis B carrier, your HBsAg level of 284.2 is indeed concerning, as it suggests that the virus is present in your bloodstream and may be replicating. The normal range for HBsAg is typically below 0.9, and values above this threshold indicate an active infection.
When interpreting HBsAg levels, it is essential to consider them in conjunction with other liver function tests, such as alanine aminotransferase (ALT or GPT) and aspartate aminotransferase (AST or GOT). These enzymes are released into the bloodstream when liver cells are damaged, and elevated levels can indicate liver inflammation or damage. In your case, since your GOT and GPT levels are normal, it suggests that your liver function is stable despite the elevated HBsAg.

The decision to initiate antiviral therapy depends on several factors, including your HBsAg level, the presence of liver inflammation (as indicated by elevated liver enzymes), the level of HBV DNA (viral load), and the overall health of your liver. If your liver function tests remain normal and there are no signs of significant liver damage or inflammation, your healthcare provider may choose to monitor your condition rather than start antiviral treatment immediately.

However, if your HBsAg levels continue to rise or if you develop symptoms of liver disease (such as jaundice, fatigue, or abdominal pain), it may be necessary to consider antiviral therapy. Common antiviral medications for Hepatitis B include tenofovir and entecavir, which are effective in suppressing the virus and reducing liver inflammation.

It's also crucial to understand how you may have contracted the virus. Hepatitis B is primarily transmitted through contact with infectious body fluids, such as blood, semen, or vaginal secretions. This can occur through unprotected sexual contact, sharing needles, or from mother to child during childbirth. If you were previously unaware of your Hepatitis B status, it's possible that you were infected at some point in the past without realizing it.

In terms of managing your health, regular follow-ups with your healthcare provider are essential. This includes routine blood tests to monitor your liver function and HBsAg levels, as well as imaging studies like ultrasound to assess liver health. Lifestyle modifications, such as maintaining a balanced diet, avoiding alcohol, and managing stress, can also support liver health.

In summary, while your elevated HBsAg level is a cause for concern, the decision to start antiviral therapy should be made in consultation with your healthcare provider, taking into account your overall health and liver function. Regular monitoring and lifestyle adjustments will also play a crucial role in managing your Hepatitis B infection effectively.