Tongue Ulcers: Causes, Symptoms, and Treatments - Otolaryngology

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Tongue ulceration?


Hello Doctor: Recently, I have been experiencing frequent sores in my mouth, particularly on my tongue.
One sore doesn't heal before another appears.
Initially, I thought it was due to work-related stress, but after two weeks, I have reached a record of having four sores on my tongue at the same time, mostly occurring on the underside and the edges.
Despite drinking more juice and supplementing with vitamin C, there has been little improvement.
This is the first time I have encountered this issue.
My lifestyle is normal, and I sleep about 7 hours a night.
I do not smoke, use drugs, drink alcohol, or engage in any risky behaviors (except for having a long-term history of psoriasis).
I am concerned that there may be other underlying conditions.
Please give me some advice.
Thank you.

A-Hsing, 20~29 year old female. Ask Date: 2006/05/18

Dr. Ye Dawei reply Otolaryngology


1.
Treatment methods:
1.
You can visit the outpatient clinic where the physician will apply AgNO3 to the inflamed area.

2.
Alternatively, you can use Kenalog ointment.
This article will be organized in the future on the 【Yeh Da-Wei ENT Clinic website/Health Education】 and published weekly in the electronic newsletter.
Articles on this website are welcome to be cited, but please indicate the source.
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The term "mouth sores" should actually be "mouth ulcers." However, since today's topic is "mouth sores," we will borrow this phrase.
In the ENT outpatient clinic, we often encounter patients of all ages and backgrounds with this issue.
Although it may seem like a minor problem, mouth sores can cause significant discomfort for patients.
Similarly, do not underestimate these seemingly harmless sores, as they can be indicative of several conditions that require careful differential diagnosis.
Below are some common mouth sore conditions encountered in the ENT clinic, including chickenpox, hand-foot-and-mouth disease, herpetic pharyngitis, herpetic gingivostomatitis, herpes labialis, and recurrent aphthous ulcers.
Only the first two (chickenpox and hand-foot-and-mouth disease) may present with skin rashes on the patient, which aids in rapid differential diagnosis.
◎ Chickenpox: The causative agent is the varicella-zoster virus.
Diagnosing chickenpox is not particularly challenging, as it has a characteristic feature where different types of skin rashes (macules, papules, vesicles, pustules, etc.) can be seen simultaneously on the same area.
Patients typically report itching but not pain, with rashes concentrated on the trunk, shoulders, face, and limbs.
◎ Hand-foot-and-mouth disease: The causative agents are the Coxsackie viruses from the enterovirus group, particularly types A4, A5, A9, A10, A16, and B2, B5, with the more notorious enterovirus 71 being less common.
As the name suggests, the rashes are distributed on the oral mucosa and the extremities of the hands and feet, causing mild itching or pain, and often leading to oral ulcers that make eating difficult.
◎ Herpetic gingivostomatitis: The causative agent is the herpes simplex virus.
Ulcers are primarily located in the anterior part of the oral cavity, with swollen gums that bleed upon contact being common, and a foul odor in the mouth is characteristic.
Additionally, if the child has atopic dermatitis, special attention should be paid to the potential complication of "herpetic eczema," which can lead to bacterial infections, with reported mortality rates of 1% to 9%.
◎ Herpetic pharyngitis: Despite being named "herpetic" pharyngitis, the causative agent is unrelated to the herpes virus; it is caused by Coxsackie viruses from the enterovirus group (types 1 to 10, 16, 22).
Ulcers are typically found in the posterior part of the oral cavity, without the swollen gums and foul odor characteristic of herpetic gingivostomatitis, making it easier to differentiate.
◎ Recurrent aphthous ulcers: There is no specific causative agent.
This is the main topic of this article and is what is truly referred to as "mouth sores." Many people have experienced this condition, where yellowish-white depressions of varying sizes appear in the oral cavity, soft and hard palates, or lips.
If not treated specifically, these can sometimes take up to two weeks to heal on their own.
This condition tends to recur intermittently, initially presenting with mild pain or burning sensation, but not as severely as the systemic discomfort associated with herpes simplex.
Many patients become adept at predicting when and where they might experience an outbreak.
It starts with a red papule, which then erodes to form an ulcer.
The ulcer gradually enlarges, causing increased pain, and patients begin to complain about its impact on eating, sleeping, mood, and speaking.
After 7 to 10 days, the ulcer heals slowly without leaving any scars, and the injured mucosa returns to normal.
The occurrence of this condition is often seen in students during exams, business people during financial stress, or elderly individuals with anxious personalities, indicating that stress, pressure, or anxiety can trigger outbreaks.
There is also a familial tendency, with entire families seeking treatment together, and some female patients may notice a correlation with their menstrual cycles.
Regarding patients' inquiries about whether it is related to vitamin deficiencies, it is difficult to substantiate this claim in today's affluent society, where nutritional excess is more common than deficiency.
It is generally accepted that factors such as mental stress lead to changes in immune function, resulting in autoimmune lesions.
The following table outlines the classification and treatment methods for recurrent aphthous ulcers:
| Type | Mild | Severe |
|---------------|-----------------------|-----------------------|
| Number | 1-5 | 1-10 | >50 |
| Size | <1 cm | 1-3 cm | Not specified |
| Location | Non-keratinized oral mucosa | Non-keratinized oral mucosa and soft palate, oropharynx | Whole mouth affected |
| Duration | 4-14 days | <6 weeks | Not specified |
| Scarring | No | Possible | Not specified |
| Incidence | Highest | Second highest | Lowest |
| Treatment | Topical corticosteroid ointment or oral corticosteroids may be added | Oral corticosteroids are required |

Reply Date: 2006/05/18

More Info


Understanding tongue ulcers can be quite complex, as they can arise from various causes and manifest with different symptoms. Tongue ulcers, also known as canker sores or aphthous ulcers, are painful lesions that can appear on the tongue or other areas of the mouth. They can significantly affect one’s quality of life, especially when they recur frequently or are particularly painful.


Causes of Tongue Ulcers
1. Stress and Anxiety: As you mentioned, stress can be a significant trigger for tongue ulcers. Psychological stress can lead to changes in the immune system, making the body more susceptible to infections and inflammatory conditions.

2. Nutritional Deficiencies: Deficiencies in certain vitamins and minerals, particularly vitamin B12, folic acid, iron, and zinc, can lead to the development of ulcers. Although you are supplementing with vitamin C, it may be beneficial to evaluate your overall diet to ensure you are getting adequate amounts of these essential nutrients.

3. Trauma: Physical injury to the tongue, such as biting it accidentally or irritation from sharp teeth or dental appliances, can lead to ulcer formation.

4. Medical Conditions: Certain underlying health conditions, such as autoimmune diseases (like Behçet's disease or lupus), gastrointestinal diseases (like Crohn's disease or celiac disease), and even chronic skin conditions like psoriasis, can manifest as recurrent ulcers in the mouth.

5. Hormonal Changes: Fluctuations in hormones, particularly in women, can also trigger the development of ulcers.

6. Infections: Viral infections, such as herpes simplex virus, can cause painful sores on the tongue and other areas of the mouth.


Symptoms of Tongue Ulcers
The primary symptom of tongue ulcers is pain, which can be exacerbated by eating, drinking, or speaking. Other symptoms may include:
- Swelling and redness around the ulcer
- A burning or tingling sensation before the ulcer appears
- Difficulty eating or swallowing due to pain
- In some cases, fever or malaise if the ulcers are associated with a viral infection.


Treatment Options
1. Topical Treatments: Over-the-counter topical anesthetics, such as benzocaine, can provide temporary relief from pain. Additionally, corticosteroid ointments may help reduce inflammation and promote healing.

2. Oral Rinses: Antimicrobial mouthwashes or saltwater rinses can help keep the area clean and may reduce the risk of secondary infections.

3. Dietary Adjustments: Avoiding spicy, acidic, or abrasive foods can help minimize irritation. Instead, focus on a soft diet that is easier to tolerate.

4. Nutritional Supplements: If deficiencies are suspected, consider consulting a healthcare provider for appropriate blood tests and potential supplementation.

5. Stress Management: Since stress can exacerbate ulcers, incorporating stress-reducing techniques such as mindfulness, yoga, or regular physical activity may be beneficial.

6. Medical Evaluation: Given that you have a history of psoriasis and are experiencing recurrent ulcers, it may be wise to consult a healthcare professional for a thorough evaluation. They may recommend further testing to rule out any underlying conditions that could be contributing to your symptoms.


Conclusion
In summary, tongue ulcers can be caused by a variety of factors, including stress, nutritional deficiencies, trauma, and underlying medical conditions. While they can be painful and disruptive, there are several treatment options available to help manage symptoms and promote healing. If your symptoms persist or worsen, it is essential to seek medical advice to ensure that there are no underlying health issues that need to be addressed. Regular follow-ups with a healthcare provider can help monitor your condition and adjust treatment as necessary.

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