Hepatitis B: Testing and Vaccination Guidance - Internal Medicine

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Hepatitis B


Over a year ago, I underwent a school health check, and I was informed that I had no antibodies and needed to get vaccinated.
However, I missed the vaccination due to a cold.
Now, after some time has passed, I would like to know which department I should visit.
Should I get tested again or go directly for the vaccination?

Fen, 20~29 year old female. Ask Date: 2006/06/05

Dr. Hong Hongchang reply Internal Medicine


Please schedule an appointment with either Family Medicine or Gastroenterology.
First, perform a blood test to check for the presence of antibodies.
If antibodies are not present, then proceed with the administration of the Hepatitis B vaccine.

Reply Date: 2006/06/05

More Info


Understanding Hepatitis B is crucial for maintaining liver health and preventing potential complications associated with the virus. Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic diseases. The primary mode of transmission is through contact with infectious body fluids, such as blood, semen, or vaginal secretions.
When it comes to testing for Hepatitis B, the most common initial test is the Hepatitis B surface antigen (HBsAg) test. A positive HBsAg result indicates that a person is currently infected with the virus. In contrast, the presence of Hepatitis B surface antibodies (Anti-HBs) indicates recovery and immunity from the virus, either through vaccination or past infection. If you have previously been tested and found to have no antibodies, it suggests that you have not been exposed to the virus or vaccinated effectively.

In your case, since you mentioned that you did not receive the vaccination due to illness, it is advisable to consult with a healthcare provider, specifically a specialist in infectious diseases or a hepatologist (liver specialist). They can guide you through the necessary steps based on your health history and current situation.

Before proceeding with vaccination, it is prudent to undergo a blood test to check your current HBsAg and Anti-HBs levels. This will help determine if you have been exposed to the virus since your last test. If you are still negative for both HBsAg and Anti-HBs, it indicates that you are susceptible to Hepatitis B and should proceed with vaccination. The Hepatitis B vaccine is typically administered in a series of three shots over a six-month period.

If your test results show that you have been exposed to the virus (i.e., HBsAg positive), further evaluation will be necessary to determine the extent of the infection and whether you require treatment. In this case, vaccination would not be appropriate, as it is designed for those who are not infected.

In summary, here are the steps you should consider:
1. Consult a Healthcare Provider: Schedule an appointment with a specialist in infectious diseases or a hepatologist.


2. Get Tested: Request a blood test to check your HBsAg and Anti-HBs levels. This will provide clarity on your current status regarding Hepatitis B.

3. Follow Recommendations: Based on the test results, your healthcare provider will advise whether you should proceed with vaccination or if further evaluation is needed.

4. Vaccination: If you are confirmed to be negative for both HBsAg and Anti-HBs, you can proceed with the Hepatitis B vaccination series.

5. Regular Monitoring: If you have any risk factors for Hepatitis B or if you are in a high-risk group, regular monitoring and follow-up with your healthcare provider are essential.

Understanding your Hepatitis B status is vital for your health and the health of those around you. Taking proactive steps now can help prevent future complications and ensure that you are protected against this potentially serious infection.

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