Liver Health: Concerns About Elevated Liver Enzymes and Tumors - Gastroenterology and Hepatology

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A concerning issue?


Hello doctor, I went to the hospital for a blood test to check my liver function because I felt fatigued.
I also had an abdominal ultrasound.
The doctor said I do not have hepatitis B or C, but my liver enzymes are 299 and 69, which is a bit strange.
Additionally, the ultrasound found a suspected hemangioma, so the doctor directly recommended a liver biopsy.
Does this mean the doctor suspects that this hemangioma is unusual? Is there a concern that it could be liver cancer? I didn't ask how large the hemangioma is, and the doctor didn't mention it.
Also, is the liver biopsy performed with a fine needle painful? What is the process like? I'm very worried...

Guo Qiang, 30~39 year old female. Ask Date: 2006/06/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, Guoqiang: Liver biopsy is an important method to directly obtain liver (tumor) cells to confirm the cause of the condition.
It has a high safety profile, so there is no need to worry.
Please discuss the details with your physician.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2006/06/08

More Info


Hello! It's understandable to feel anxious when faced with health concerns, especially regarding liver health. Elevated liver enzymes and the discovery of a mass in the liver can indeed raise questions and worries. Let's break down your situation and address your concerns.


Elevated Liver Enzymes
You mentioned that your liver enzyme levels are elevated, with values of 299 for AST (aspartate aminotransferase) and 69 for ALT (alanine aminotransferase). Normal ranges for these enzymes are typically below 40 U/L, so your levels are significantly elevated. Elevated liver enzymes can indicate liver inflammation or damage, which can be caused by various factors, including viral hepatitis, fatty liver disease, alcohol consumption, medications, or other liver diseases.

Since your tests for Hepatitis B and C came back negative, this suggests that viral hepatitis is not the cause of your elevated liver enzymes. Other potential causes could include non-alcoholic fatty liver disease (NAFLD), autoimmune hepatitis, or even medication-induced liver injury. It’s essential to follow up with your healthcare provider to determine the underlying cause of the elevated enzymes.


Discovery of a Liver Mass
The ultrasound finding of a suspected hemangioma (a benign vascular tumor) is also noteworthy. Hemangiomas are the most common benign tumors of the liver and are usually asymptomatic. They often do not require treatment unless they cause symptoms or complications. However, the concern arises when a liver mass is detected, as it can sometimes be challenging to differentiate between benign and malignant lesions based solely on imaging studies.

Your doctor’s recommendation for a liver biopsy indicates that they want to obtain a definitive diagnosis regarding the nature of the mass. A biopsy can help determine whether the mass is indeed a hemangioma or something more concerning, such as a malignant tumor (like liver cancer).

Liver Biopsy Procedure
Regarding the liver biopsy, it is typically performed using a thin needle to extract a small sample of liver tissue. This procedure can be done under ultrasound guidance to ensure accuracy. While some discomfort is expected, many patients report that the pain is manageable and brief. The procedure usually takes about 15-30 minutes, and you may be asked to lie on your back or side during the biopsy.

After the biopsy, you will be monitored for a short period to ensure there are no complications, such as bleeding. Most people can go home the same day, but you may need to avoid strenuous activities for a short period afterward.


Concerns About Cancer
It's natural to worry about the possibility of cancer when a mass is found in the liver. However, it's important to remember that not all liver masses are cancerous. Hemangiomas, as mentioned earlier, are benign and quite common. The biopsy will provide clarity on this matter.
In the meantime, focus on maintaining a healthy lifestyle, including a balanced diet, regular exercise, and avoiding alcohol, as these can support liver health.

Conclusion
In summary, while elevated liver enzymes and the discovery of a liver mass can be concerning, they do not automatically indicate cancer. The liver biopsy will provide crucial information to guide your diagnosis and treatment plan. It’s essential to communicate openly with your healthcare provider about your concerns and to follow their recommendations for further evaluation and management.
Remember, early detection and intervention are key to managing liver health effectively. If you have any more questions or need further clarification, don’t hesitate to reach out to your healthcare team. They are there to support you through this process.

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