Penile Health: Common Concerns and Symptoms Explained - Urology

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When it comes to penile health, it’s essential to understand the anatomy and potential concerns that can arise. Based on your description, it seems you are referring to the area known as the "groin" or "inguinal region," which is the area where the thigh meets the abdomen. This region is often associated with various conditions, including hernias and lymphadenopathy, but in your case, it seems you are more concerned about a specific lesion near the penis.

The round, soft, dark bump you described near your foreskin that has changed in size and has been associated with discharge (both pus and blood) raises several possibilities. While I cannot provide a definitive diagnosis without a physical examination, I can outline some common conditions that may be relevant to your situation:
1. Pearly Penile Papules: These are small, harmless bumps that can appear around the corona of the glans (the head of the penis). They are normal anatomical variations and are not associated with any disease.

2. Sebaceous Cysts: These are small, soft lumps that can occur on the skin, including the genital area. They are filled with a fatty substance and can sometimes become inflamed or infected, leading to discharge.

3. Folliculitis: This is an inflammation of the hair follicles that can occur anywhere on the body, including the genital area. It can present as small, red bumps that may be painful or itchy.

4. Genital Warts (Condylomata Acuminata): Caused by the human papillomavirus (HPV), these can appear as soft, fleshy growths. They can vary in size and may be mistaken for other lesions. Given your concern about sexually transmitted infections (STIs), this is a possibility to consider.

5. Herpes Simplex Virus (HSV): This can cause painful blisters or sores in the genital area. If you have had previous outbreaks, this could be a recurrent infection.

6. Other STIs: While you mentioned that tests for HIV and syphilis were negative, other infections like gonorrhea or chlamydia can also present with unusual lesions or discharge.

Given that you have experienced changes in the lesion, including it becoming larger and then smaller, and the presence of discharge, it is crucial to seek medical attention from a healthcare provider, preferably a urologist or a dermatologist specializing in genital health. They can perform a thorough examination, possibly including a biopsy if necessary, to determine the exact nature of the lesion.

In the meantime, it is advisable to avoid manipulating the lesion further, as this can lead to infection or worsen any existing condition. Maintaining good hygiene and avoiding irritants in the area can also help.

Lastly, while it is understandable to feel anxious about potential STIs, it is important to remember that many conditions can cause similar symptoms, and not all are sexually transmitted. Open communication with your healthcare provider about your concerns and symptoms will help in getting the appropriate diagnosis and treatment.