Managing Pain and Symptoms After Stage IV Colon Cancer Surgery and Chemotherapy - Oncology

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My aunt underwent a tumor resection surgery for stage IV colon cancer (which has metastasized to the liver) about a month ago (July 4).
Last Thursday (July 27), she received her second round of chemotherapy.
On the first day after the treatment, she felt very good, but starting Saturday (July 29), her energy levels began to decline, and by this Monday, she was almost unable to stand due to extreme fatigue and body aches.
She experiences a sensation in her abdomen as if being pricked by needles, occasional nausea, and has been vomiting clear fluid.
That evening, she went to the emergency room, where tests revealed elevated potassium levels.
She was observed in the hospital for two days, during which it was found that the cancer cells in her liver are very active.
An anesthesiologist prescribed magnesium oxide tablets, Xanax, clonazepam capsules, and a long-acting antihistamine for her to take at home.
She is also still taking medications prescribed by her primary physician, including Carbinoxamine tablets, Gut Relief coated tablets, progesterone, and two types of vitamins.
Over the past two days, she continues to feel unwell, has little appetite, is unable to walk, occasionally has a slight fever, and has very little urine output, feeling as though she is unable to urinate properly.
We are unsure about this situation.
Additionally, could you please advise on how to consult her primary physician outside of outpatient services, or if there are direct consultation channels available? Thank you.

Xin Xian Ren, 20~29 year old female. Ask Date: 2006/08/04

Dr. Chen Sirong reply Oncology


Hello: 1.
It is likely a side effect of chemotherapy.
2.
The patient's condition is best understood by the primary physician, so I recommend asking the patient's attending physician if they can be contacted for consultation outside of outpatient hours.
3.
Finally, I suggest considering the use of Young or other supplements, which may help her feel more comfortable.
Sincerely, Dr.
Chen Sih-Rong, Oncology.

Reply Date: 2006/08/04

More Info


Managing pain and symptoms after surgery and chemotherapy for Stage IV colon cancer can be a complex and challenging process, especially when the cancer has metastasized to other organs, such as the liver. Your aunt's situation, where she has undergone tumor resection and is currently receiving chemotherapy, is not uncommon, but it does require careful management to ensure her comfort and quality of life.

Firstly, it is important to understand that the symptoms your aunt is experiencing—fatigue, pain, nausea, and changes in appetite—are common side effects of both surgery and chemotherapy. The fatigue can be exacerbated by the body’s response to cancer and the stress of treatment. Pain, particularly if it feels sharp or stabbing, may indicate irritation or inflammation in the abdominal area, possibly related to the surgery or the underlying disease. Nausea and vomiting can also be side effects of chemotherapy, and they can significantly impact a patient's ability to eat and maintain strength.

The elevated potassium levels that were discovered during her emergency visit could be a result of various factors, including dehydration, kidney function issues, or side effects from medications. High potassium levels can be serious and require monitoring and management, as they can affect heart function. It is crucial that her healthcare team is aware of these changes and can adjust her treatment plan accordingly.

In terms of managing her symptoms, there are several strategies that can be employed:
1. Pain Management: It is essential to address her pain effectively. This may involve the use of analgesics, which can range from over-the-counter medications like acetaminophen or ibuprofen to stronger prescription opioids if necessary. The healthcare team may also consider adjunct therapies such as nerve blocks or palliative care consultations to help manage pain more effectively.

2. Nausea and Vomiting: Antiemetic medications can be prescribed to help control nausea and vomiting. Medications such as ondansetron or metoclopramide are commonly used. Additionally, dietary modifications, such as eating small, frequent meals and avoiding strong odors, can help manage these symptoms.

3. Nutritional Support: Maintaining nutrition is crucial, especially after surgery and during chemotherapy. If oral intake is insufficient, nutritional supplements or even enteral feeding (via a feeding tube) may be considered. Consulting with a dietitian specialized in oncology can provide tailored advice to meet her nutritional needs.

4. Hydration: Ensuring adequate hydration is vital, particularly if she is experiencing vomiting or has reduced fluid intake. Intravenous fluids may be necessary if oral hydration is not sufficient.

5. Monitoring and Follow-Up: Regular follow-up appointments with her oncologist are critical to monitor her response to treatment and manage any side effects. If she is unable to attend in-person appointments, telehealth options may be available for consultations.

6. Emotional and Psychological Support: The emotional toll of cancer treatment should not be overlooked. Support from mental health professionals, support groups, or counseling can provide significant benefits.

Regarding your question about contacting her primary physician outside of regular office hours, many healthcare systems have protocols for urgent questions. It is advisable to check if her oncologist's office has a dedicated line for after-hours concerns or if they utilize a patient portal where messages can be sent directly to the healthcare team.

In conclusion, managing the symptoms and pain associated with Stage IV colon cancer requires a comprehensive approach that includes medication management, nutritional support, hydration, and emotional care. Open communication with her healthcare team is essential to ensure that her needs are met and that she receives the best possible care during this challenging time.

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