Painful Blisters Near the Urethra: What You Need to Know - Urology

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Hello Dr.
Chen, I have had a blister near the urethral opening on my glans for several years.
It didn't hurt or itch when pressed, so I didn't pay much attention to it.
Recently, it suddenly increased in size and is now about one centimeter big.
It didn't hurt a couple of days ago, but now it feels painful when I press on it.
The original color was red, but now the blister has turned slightly white.
I visited a doctor last week, and they prescribed an ointment for me to apply, but it doesn't seem to be effective.
I am unsure what this growth on my body is, and I am feeling a lot of psychological stress.
I hope the doctor can provide some answers.
I have also scheduled an appointment with the doctor.
Thank you.

husky, 20~29 year old female. Ask Date: 2006/08/06

Dr. Chen Xiuyi reply Urology


Hello: Based on your description, the most likely cause is a paraurethral cyst, which may cause swelling and pain if accompanied by an infection.
If infections recur or affect urination, surgical treatment should be considered.
It is best to continue seeking medical care.
Sincerely, Dr.
Chen Hsiu-Yi, Urology.

Reply Date: 2006/08/06

More Info


Hello! Thank you for reaching out with your concerns regarding the blister near your urethra. It's understandable to feel anxious about changes in your body, especially when it comes to sensitive areas. Let's break down your situation and discuss what you might be experiencing.

From your description, it sounds like you have a blister that has changed in size and sensation over time. Initially, it was painless and not bothersome, but now it has increased in size to about one centimeter and has become painful when pressed. The color change from red to a whitish appearance inside the blister is also noteworthy.
There are several potential causes for a blister in that area, and while I cannot provide a definitive diagnosis without a physical examination, I can outline some possibilities:
1. Infection: Blisters can sometimes be caused by infections, such as herpes simplex virus (HSV), which can lead to painful sores. If the blister is filled with fluid and has changed in color, it could indicate an infection that may require antiviral medication.

2. Folliculitis: This is an inflammation of the hair follicles, which can occur in the genital area and may present as small, painful bumps or blisters.

3. Cysts: Sebaceous cysts can develop in the genital area and may appear as painless lumps that can become inflamed or infected, leading to pain and changes in size.

4. Allergic Reaction or Irritation: Sometimes, contact dermatitis from soaps, lotions, or other irritants can cause blisters to form. If you've changed any products recently, this could be a factor.

5. Other Dermatological Conditions: Conditions like psoriasis or eczema can also manifest in the genital area, leading to blister-like lesions.

Given that you have already seen a doctor and received a topical treatment that hasn't shown improvement, it’s crucial to follow up with your healthcare provider. They may consider further evaluation, such as a culture of the blister fluid or a biopsy, to determine the exact cause.
In the meantime, here are some general recommendations:
- Avoid Irritation: Try to keep the area clean and dry. Avoid tight clothing that may rub against the blister.

- Do Not Pop the Blister: Popping it can lead to infection and worsen the situation.

- Monitor Symptoms: Keep track of any changes in size, color, or pain level, and report these to your doctor.

- Manage Anxiety: It’s understandable to feel stressed about this situation. Consider discussing your feelings with a mental health professional or seeking support from friends and family.

Lastly, since you have already scheduled a follow-up appointment, be sure to communicate all your symptoms and concerns clearly to your doctor. They are best equipped to provide you with the appropriate care and treatment options based on a thorough examination.

Take care, and I hope you find relief soon!

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