The Importance and Methods of Treating Helicobacter Pylori Infections

The necessity and methods of Helicobacter pylori treatment?

Hello Dr.
Chen,
My husband’s health check revealed an excessive amount of Helicobacter pylori, with a level of 12.62.
He does not have any specific discomfort, but his gastrointestinal system is quite sensitive, and he tends to experience diarrhea after consuming contaminated or problematic food.
Is it necessary for him to undergo medication treatment? Additionally, I have heard that the medications covered by health insurance are not very effective, and it is better to self-pay for a triple therapy medication.
After taking the medication continuously for one week, how long should we wait before retesting? Is there such a thing as false positives and false negatives? Can a long-term excess of Helicobacter pylori lead to gastric ulcers or stomach cancer? Thank you.

Mrs. Ji, 40~49 year old female. Ask Date: 2006/08/20

Dr. Chen Shidian reply Gastroenterology and Hepatology

Dear Mrs.
Ji,
1.
Helicobacter pylori is quite common, with approximately half of the population in Taiwan being infected.
There is no need to panic, as it is not related to diarrhea but is associated with gastric ulcers and gastric cancer.
2.
If you wish to eradicate the bacteria, the National Health Insurance regulations require that a gastroscopy report indicating gastric or duodenal ulcers is necessary for medication coverage; otherwise, you will need to pay out of pocket (approximately over two thousand NTD).
3.
It is generally recommended that individuals with gastric pain symptoms undergo a gastroscopy first.
If there are no symptoms but a family history of gastric cancer exists, then you may consider self-paying for eradication treatment.
4.
After eradication, blood tests may still show a positive reaction, which indicates a positive result; therefore, there is no need for further blood tests.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2006/08/20

More Info

Helicobacter pylori (H. pylori) is a type of bacteria that can infect the stomach and is known to be a significant cause of various gastrointestinal disorders, including chronic gastritis, peptic ulcers, and even gastric cancer. The importance of treating H. pylori infections cannot be overstated, as untreated infections can lead to serious health complications over time.

Importance of Treating H. pylori Infections
1. Prevention of Gastric Ulcers: H. pylori is a primary cause of peptic ulcers. If left untreated, these ulcers can lead to more severe complications, such as bleeding or perforation of the stomach lining.

2. Reduction of Gastric Cancer Risk: There is a well-established link between H. pylori infection and gastric cancer. Studies have shown that individuals with chronic H. pylori infection have a significantly higher risk of developing gastric cancer compared to those without the infection.

3. Improvement of Gastrointestinal Symptoms: Even in asymptomatic individuals, the presence of H. pylori can lead to gastrointestinal discomfort, such as bloating, nausea, and sensitivity to certain foods. Treating the infection can alleviate these symptoms.

4. Long-term Health Benefits: Successfully eradicating H. pylori can lead to improved overall gastrointestinal health and reduce the risk of future complications.

Methods of Treating H. pylori Infections
The standard treatment for H. pylori infection typically involves a combination of antibiotics and proton pump inhibitors (PPIs). The most common regimens include:
1. Triple Therapy: This involves a PPI (such as omeprazole or esomeprazole), along with two antibiotics (commonly amoxicillin and clarithromycin) for a duration of 10 to 14 days. This regimen is effective in eradicating the bacteria in most cases.

2. Quadruple Therapy: In cases where triple therapy fails or in areas with high resistance to clarithromycin, a quadruple therapy may be used. This includes a PPI, bismuth subsalicylate, and two antibiotics (such as metronidazole and tetracycline).

3. Sequential Therapy: This involves a two-phase treatment where a PPI and amoxicillin are given for the first five days, followed by a PPI, clarithromycin, and amoxicillin for the next five days.

Considerations for Treatment
- Asymptomatic Patients: In your husband's case, while he may not exhibit severe symptoms, the high level of H. pylori (12.62) suggests that treatment is advisable to prevent potential complications in the future, even if he currently feels well.

- Effectiveness of Medications: While some may express concerns about the effectiveness of government-subsidized medications, studies generally support the efficacy of these treatments. However, if there are concerns about resistance or effectiveness, discussing alternative options with a healthcare provider is essential.

- Follow-up Testing: After completing the treatment, it is recommended to wait at least four weeks before undergoing follow-up testing to confirm eradication of the bacteria. This allows sufficient time for the stomach lining to heal and for the antibiotics to clear from the system.

- False Positives and Negatives: There is a possibility of false positives and negatives in H. pylori testing. Factors such as recent antibiotic use or the presence of other gastrointestinal conditions can affect test results. It is crucial to discuss any concerns with your healthcare provider.

Long-term Risks
Long-term H. pylori infection can lead to chronic gastritis, peptic ulcers, and an increased risk of gastric cancer. Therefore, addressing the infection promptly is crucial for maintaining gastrointestinal health and preventing future complications.

In conclusion, treating H. pylori infections is vital for preventing serious health issues, even in asymptomatic individuals. The standard treatment regimens are effective, and follow-up testing is essential to ensure successful eradication of the bacteria. If you have further concerns or questions, consulting with a gastroenterologist would be beneficial for personalized advice and treatment options.

Similar Q&A

Effective Treatment for Stomach Pain Caused by H. Pylori Infection

If you have stomach pain caused by Helicobacter pylori, the treatment typically involves a combination of antibiotics and acid-reducing medications. The standard regimen usually includes: 1. Two different antibiotics (such as amoxicillin and clarithromycin) to eradicate the bact...

Dr. Chen Shidian reply Internal Medicine
In Taiwan, studies show that approximately 50-60% of people are infected with Helicobacter pylori, but only a few require treatment, such as: 1. Ulcers confirmed by gastroscopy 2. Specific gastric lymphoma 3. Other cases (where health insurance does not cover the medication costs...

Effective Treatment Options for Helicobacter Pylori Infection and Gastritis

I underwent an upper gastrointestinal endoscopy in February of this year, and the results showed chronic superficial gastritis with Helicobacter pylori infection. What is the recommended treatment?

Dr. Chen Qifeng reply Gastroenterology and Hepatology
Hello: For patients with gastritis combined with Helicobacter pylori, treatment guidelines recommend that only those with refractory gastritis should undergo bacterial eradication therapy for Helicobacter pylori. Wishing you peace and health. Sincerely, Dr. Chi-Feng Chen, Departm...

Innovative IGY Immunoglobulin Treatment for Helicobacter Pylori Infection

Hello, Doctor. My father is currently 45 years old and works as a taxi driver. He suffers from gastroesophageal reflux disease (GERD). In July of last year, he underwent an examination and was found to have acid reflux caused by Helicobacter pylori. He was treated with a triple t...

Dr. Hong Hongchang reply Internal Medicine
Hello Sophia: The prevalence of Helicobacter pylori in Taiwan is increasing, and it has been found to be associated with atrophic gastritis and early gastric lymphoma. The current standard treatment regimen involves a triple therapy or quadruple therapy for one to two weeks, foll...

Understanding Helicobacter Pylori: Types, Treatment, and Dietary Considerations

Thank you, Dr. Ke, for your response regarding the issues of gastric ulcers and peritonitis. I would like to inquire about the treatment of Helicobacter pylori: 1. How many types of Helicobacter pylori are there, and what are the treatment options? 2. After a gastric ulcer causes...

Dr. Ke Fangxu reply Surgery
Helicobacter pylori is the only bacterium that can cause gastric ulcers, and treatment requires a one-week course of oral antibiotics (triple therapy). 2. Severe gastric ulcers can lead to gastric perforation, which may subsequently cause peritonitis. Treatment for Helicobacter p...